Thermodynamic Network Analysis of Biological Systems
Thermodynamic Network Analysis of Biological Systems

Author: J. Schnakenberg

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 157

ISBN-13: 3642679714

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The first edition of this book was greeted with broad interest from readers en gaged in various disciplines of biophysics. I received many stimulating and en couraging responses, however, some of the book's reviewers wanted to stress the fact that an extensive literature of network theory was not included or reported in the book. But the main aspect of the book is intended to be substantive rather than methodical: networks simply serve as a remedy for doing some first steps in analysing and modelling complex biological systems. For an advanced stage in the investigation of a particular system it may be appropriate to replace the pheno menological network method by more detailed techniques like statistical equations or computer simulations. According to this intention, the second edition of the book has been enlarged by further biological examples for network analysis, not by more network theory. There is a completely new section on a network model for photoreception. For this section I am obliged to J. Tiedge who did most of the detailed calculation and to my colleague Professor Stieve with whom we have had a very fruitful cooperation. Also I would like to mention that this work has been sponsored by the "Deutsche Forschungsgemei nschaft" i n the "Sonderforschungsberei ch 160". Recent results for excitable systems represented by feedback networks have also been included in the second edition, especially for limit cycle networks.

Biological Network Analysis
Biological Network Analysis

Author: Pietro Hiram Guzzi

Publisher: Elsevier

Published: 2020-05-11

Total Pages: 212

ISBN-13: 0128193514

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Biological Network Analysis: Trends, Approaches, Graph Theory, and Algorithms considers three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN), and Human Brain Connectomes. The book's authors discuss various graph theoretic and data analytics approaches used to analyze these networks with respect to available tools, technologies, standards, algorithms and databases for generating, representing and analyzing graphical data. As a wide variety of algorithms have been developed to analyze and compare networks, this book is a timely resource. - Presents recent advances in biological network analysis, combining Graph Theory, Graph Analysis, and various network models - Discusses three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN) and Human Brain Connectomes - Includes a discussion of various graph theoretic and data analytics approaches

Biophysics
Biophysics

Author: Roland Glaser

Publisher: Springer Science & Business Media

Published: 2012-04-23

Total Pages: 424

ISBN-13: 3642252125

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Biophysics is the science of physical principles underlying all processes of life, including the dynamics and kinetics of biological systems. This fully revised 2nd English edition is an introductory text that spans all steps of biological organization, from the molecular, to the organism level, as well as influences of environmental factors. In response to the enormous progress recently made, especially in theoretical and molecular biophysics, the author has updated the text, integrating new results and developments concerning protein folding and dynamics, molecular aspects of membrane assembly and transport, noise-enhanced processes, and photo-biophysics. The advances made in theoretical biology in the last decade call for a fully new conception of the corresponding sections. Thus, the book provides the background needed for fundamental training in biophysics and, in addition, offers a great deal of advanced biophysical knowledge.

New Methods for the Study of Biomolecular Complexes
New Methods for the Study of Biomolecular Complexes

Author: W. Ens

Publisher: Springer Science & Business Media

Published: 1998-02-28

Total Pages: 376

ISBN-13: 9780792350033

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A NATO Advanced Research Workshop entitled New Methods for the Study of Molecular Aggregates was held at Tbe Lodge at Kananaskis Village, Alberta, Canada from 16 -20 June 1996. In fact the meeting was entirely concerned with the problem of analyzing biomolecular complexes, so the title of these proceedings has been altered to give a more precise description of the content. Tbe workshop was hosted by the time-of-flight group of the Department of Physics at the University of Manitoba, and was attended by 64 participants from around the world. '!\venty-one invited talks were given and 27 papers were presented as posters. Of the 48 contributions, 22 papers (12 orals, 10 posters) are included in these proceedings. Tbe subject of the conference was the investigation of noncovalent biomolecular complexes, with particular focus on the application of mass spectrometry to their characterization. '!\vo new ionization techniques introduced in the late 1980s, electrospray ionization (ES I) and matrix-assisted laser desorptionlionization (MALDI), resulted in a breakthrough in mass spectrometry, enabling its use in molecular weight and primary structure determination of biopolymers larger than 100 kDa. Recently it has been discovered that ESI mass spectrometry mayaiso be used to characterize complexes containing noncovalent interactions, thus opening new perspectives for supramolecular chemistry. ESI mass spectrometry has the advantage that the sampie is introduced from a homogenous solution which can be maintained at near physiological conditions of pR, concentration, and temperature.

Methodologies and Applications for Chemoinformatics and Chemical Engineering
Methodologies and Applications for Chemoinformatics and Chemical Engineering

Author: Haghi, A. K.

Publisher: IGI Global

Published: 2013-05-31

Total Pages: 500

ISBN-13: 1466640111

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In recent years, significant advances have been made in the development of chemistry and computer science integration into the fields of biomedical and chemical engineering, applying quantum principles to practical, macro-world science. Methodologies and Applications for Chemoinformatics and Chemical Engineering brings together innovative research, new concepts, and novel developments in the application of informatics tools for applied chemistry and computer science. This book is essential amongst chemists, engineers, and researchers in providing mutual communication between academics and industry professionals around the world.

The Random Spatial Economy and its Evolution
The Random Spatial Economy and its Evolution

Author: Leslie Curry

Publisher: Routledge

Published: 2020-07-09

Total Pages: 767

ISBN-13: 0429764448

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First published in 1998, this volume, spanning a lifetime's research, is a highly innovative first attempt at a consistent theoretical approach to the elements, structures and dynamics of the geography of agents, settlements and trade. Cause and effect are replaced by chance within constraints. Populations are substituted for unreal representative individuals, variability for uniformity, probabilistic process for unique history. Ignorance is a major factor in interpersonal and inter-areal commercial relations so that the focus is on flows of information and their effects on the efficiency of the economy or, alternatively, on changes in its information content. Recent work on spatial arrangements in many physical and social sciences is incorporated but always interpreted from an overriding geographical viewpoint. Key concepts are locational potential, distance friction, mobility, diffusion, spatial pattern and texture, adaptability, efficiency, spatial interaction and dependence. Analytic methods include autocovariance and transfer functions, areal special densities and entropy. Various forms of self-organization of economic spatial patterns are examined.