Incretin Based Therapies
Incretin Based Therapies

Author: Sanjay Kalra

Publisher: JP Medical Ltd

Published: 2013-03-31

Total Pages: 194

ISBN-13: 9350256487

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Incretins are a group of gastrointestinal hormones that cause an increase in the amount of insulin released from cells in the pancreas after eating. Incretin based drugs are used to control blood sugar levels in the management of diabetes. This book is a concise guide to incretin based therapy. Beginning with an introduction to the history and physiology of incretins, the following sections examine the clinical pharmacology of GLP-1 Analogues and DPP-4 Inhibitors, the pleiotrophic effects of incretins and comparative pharmacology. Each section integrates science with practical therapeutic guidance for clinicians involved in the management of diabetes. The final chapter discusses the future of incretin therapies, including non-diabetic usage and combination therapy. Key Features Concise overview of incretin based therapy for the management of diabetes Guides clinicians step by step through the history and pharmacology of various molecules Integrates science with practical therapeutic guidance Includes chapter on the future of incretin therapy

Pharmacotherapy of Diabetes: New Developments
Pharmacotherapy of Diabetes: New Developments

Author: Carl Erik Mogensen

Publisher: Springer Science & Business Media

Published: 2007-10-23

Total Pages: 283

ISBN-13: 0387697373

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Diabetes is a huge and growing healthcare worry, especially in Western countries. The treatment of both types – 1 and 2 – of this disease has changed radically over the past few years. This work provides an overview of all the changes that will come to be implemented in clinical practice. Summarizing all aspects of treatment, this book delineates the large amount of research work that has been completed over the last few years into the relief of complications in diabetes and vascular medicine in general.

Medical Management of Type 2 Diabetes
Medical Management of Type 2 Diabetes

Author: Charles F. Burant

Publisher: American Diabetes Association

Published: 2012-06-05

Total Pages: 185

ISBN-13: 158040491X

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As type 2 diabetes continues its rise in prevalence worldwide, there is an increasing need to study it and describe successful treatments. There are several options for treatment, including oral medications, diet and lifestyle modification, and insulin therapy. Knowing which method to select and how to apply it relies on several clinical guidelines that are updated every year by the American Diabetes Association. This new edition of Medical Management of Type 2 Diabetes provides care providers with the answers to their questions about implementing care. All of the contributors are experts in their fields, and they define the disease, including the progressive nature of type 2 diabetes; cardiovascular, microvascular, and neurological complications; care methodologies for special situations; and behavior change. All guidelines and standards have been updated with the latest developments in research, advances in medications and medical devices, and new understandings of how to effectively work with the patient.

Managing Diabetes and Hyperglycemia in the Hospital Setting
Managing Diabetes and Hyperglycemia in the Hospital Setting

Author: Boris Draznin

Publisher: American Diabetes Association

Published: 2016-05-20

Total Pages: 338

ISBN-13: 1580406572

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As the number of patients with diabetes increases annually, it is not surprising that the number of patients with diabetes who are admitted to the hospital also increases. Once in the hospital, patients with diabetes or hyperglycemia may be admitted to the Intensive Care Unit, require urgent or elective surgery, enteral or parenteral nutrition, intravenous insulin infusion, or therapies that significantly impact glycemic control (e.g., steroids). Because many clinical outcomes are influenced by the degree of glycemic control, knowledge of the best practices in inpatient diabetes management is extremely important. The field of inpatient management of diabetes and hyperglycemia has grown substantially in the last several years. This body of knowledge is summarized in this book, so it can reach the audience of hospitalists, endocrinologists, nurses and other team members who take care of hospitalized patients with diabetes and hyperglycemia.

Core Topics in Endocrinology in Anaesthesia and Critical Care
Core Topics in Endocrinology in Anaesthesia and Critical Care

Author: George M. Hall

Publisher: Cambridge University Press

Published: 2010-04-01

Total Pages: 203

ISBN-13: 1139486128

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Core Topics in Endocrinology in Anesthesia and Critical Care provides a comprehensive, practical overview of the perioperative management of patients with endocrine disorders, giving clear diagnostic advice and management guidelines. This book considers the management of patients with endocrine disorders of the pituitary, thyroid, parathyroid and adrenal glands, including rarer disorders such as MEN syndrome. It then considers all aspects of the perioperative management of diabetic patients, including paediatric, obstetric and ambulatory patients. Finally it discusses endocrine disorders in the critically ill patient, covering such issues as the topical conundrum of glucose control and the management of diabetic metabolic acidosis, thyroid storm and myxoedema coma. Every chapter reviews the relevant anatomy and pathophysiology and the latest developments in defining the genetic causes are also considered where appropriate. Core Topics in Endocrinology in Anesthesia and Critical Care is an invaluable tool for all anaesthetists and intensivists in their daily clinical practice.

Oral Delivery of Insulin
Oral Delivery of Insulin

Author: T.A. Sonia

Publisher: Elsevier

Published: 2014-12-11

Total Pages: 361

ISBN-13: 1908818689

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Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus. Subsequent chapters cover the various routes for administering insulin; the challenges and strategies of oral delivery; experimental techniques in the development of an oral insulin carrier; lipids; inorganic nanoparticles and polymers in oral insulin delivery; and a summary and presentation of future perspectives on oral delivery of insulin. - Presents an overview of Diabetes Mellitus - Includes a discussion of various strategies and techniques adopted for oral delivery of insulin - Presents an update of research in the field

Modern Critical Care Endocrinology, An Issue of Critical Care Clinics
Modern Critical Care Endocrinology, An Issue of Critical Care Clinics

Author: Rinaldo Bellomo

Publisher: Elsevier Health Sciences

Published: 2019-04-28

Total Pages:

ISBN-13: 0323677924

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This issue of Critical Care Clinics, Guest Edited by Dr. Rinaldo Bellomo, focuses on Modern Critical Care Endocrinology. Article topics include: Diabetes insipidus and SIADH in the ICU; Estrogen therapy in ICU patients; The angiotensin family, ACE and ACE 2; Angiotensin II in vasodilatory shock; Vasopressin in vasodilatory shock; Hydrocortisone in vasodilatory shock; Erythropoietin in trauma and critical illness; HbA1c and permissive hyperglycemia in diabetic ICU patients; Osteoporosis and the critically ill patient; New oral agents for the treatment of diabetes; Melatonin in critical care; The incretins in ICU patients; Hepcidin; Thyroid hormone therapy in the ICU; and Hormonal therapy in organ donors.

The Organic Chemistry of Drug Design and Drug Action
The Organic Chemistry of Drug Design and Drug Action

Author: Richard B. Silverman

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 650

ISBN-13: 0080513379

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Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

Incretins and Insulin Secretion
Incretins and Insulin Secretion

Author:

Publisher: Academic Press

Published: 2010-12-16

Total Pages: 481

ISBN-13: 0123815347

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First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on insulin and IGFs. - Longest running series published by Academic Press - Contributions by leading international authorities