Recently, nanoparticles have shown efficacy against antimicrobial activity, including several microorganisms and those that are multidrug-resistant. Nanosensors represent an advance in the diagnosis of infectious diseases, particularly those with zoonotic risk. Different strategies using nanoparticles have been examined for both diagnosis and treatment of these diseases, as well as prevention. The optimization of detection methods and antimicrobial activity is a challenge in microbiology. Advances using nanotechnology are an emerging alternative to solve some problems in the diagnosis and therapy of veterinary infectious diseases. There are implications for the application of nanoparticles to shape interactions with the microorganism itself, as well as influence the bioavailability, biocompatibility, and biodegradation of the system with low host toxicity. The time of detection and its ability to target pathogens can be improved with nanotechnology.
Literature Review from the year 2022 in the subject Veterinary medicine, , course: Nanotechnology, language: English, abstract: The objective of this seminar paper is to review the application of nanotechnology on smart drug delivery system, in animal disease treatment and diagnosis, animal breeding and reproduction and also chicken product. Nanotechnology is an exciting and rapidly emerging technology allowing us to work at the molecular level, often atom by atom, to create and manipulate tools, materials and functional structures that have nanometer dimensions. It has the potential to have greats impact on diagnosis and treatment of animals. Unique size dependent properties of nanoparticles have numerous diagnostic applications such as diagnostic biosensors, imaging nanoprobes for magnetic resonance imaging contrast agents. Using nanotechnology multifunctional nanomaterial’s can be designed to image a specific organ, target tissue, access deep molecular targets and provide drugs at controlled release. Great advances have been and are being made in nanobiochip materials, nanoscale biomimetic materials, nanomotors, nanocomposite materials, interface biomaterials and nanobiosensors with enormous prospect in veterinary medicine application. It is a research and development aimed at understanding and working with seeing, measuring and manipulating at the atomic, molecular and supramolecular levels. This correlates to length scales of roughly 1 to 100 nanometers. At this scale, the physical, chemical and biological properties of materials differ fundamentally and often unexpectedly integrated sensing, monitoring and controlling system could detect the presence of disease and notify the farmer and veterinarian to activate a targeted treatment delivery system. This is possible with nanotechnology and could permit a wide range of advances in the field of agriculture, animal and veterinary sciences such as conversion of agricultural and food wastes to energy and other useful by-products through enzymatic nanobioprocessing, development in reproductive sciences, breeding managements, disease prevention and treatment in animals and public health. Applications of nanotechnology and nanoparticles in food, animal breeding and animal productivity such as in meat production, milk production are emerging rapidly. It used to create materials and change structure, enhanced quality and texture of foodstuffs at the molecular level. This technology has a major impact on production, processing, transportation, storage, traceability, safety and security of food.
Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. Delivers commentary from an international researcher base, providing insights across differing economic statuses Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Designed to foster a stronger awareness and exploration of the subject by practicing clinicians, medical researchers and scientists, The Clinical Nanomedicine Handbook discusses the integration of nanotechnology, biology, and medicine from a clinical point of view. The book highlights relevant research and applications by specialty; it examines nanotechnology in depth, and the potential to solve medical problems. It also increases literacy in nanotechnology, and allows for more effective communication and collaboration between disciplines. Details worldwide developments in nanomedicine Provides a comprehensive roadmap of the state of nanomedicine in numerous medical specialties Bridges the gap between basic science research, engineering, nanotechnology, and medicine This text discusses what nanomedicine is, how it is currently used, and considers its potential for future applications. It serves as a reference for clinicians, including physicians, nurses, health-care providers, dentists, scientists, and researchers involved in clinical applications of nanotechnology.
Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.
Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area
The book "Pharmacology and Therapeutics" targets every aspect of the mechanisms for the chemical actions of both traditional and novel drugs. This book covers six sections: Molecular Modeling and Bio-molecular Pharmacology, Immunopharmacology, Environmental Pharmacology and Toxicology, Nanotechnology and Chemotherapy, Drugs and Drug Delivery System and Addiction Pharmacology. Each of these sections is interwoven with the theoretical aspects and experimental techniques of physiology, biochemistry, nutrition, cellular and molecular biology, microbiology, immunology, genetics, and pathology. This book will be a significant source to scientists, physicians, health care professionals and students who are interested to explore the effect of chemical agents on human life.
Nanomaterials in Diagnostic Tools and Devices provides a complete overview of the significance of nanomaterials in fabricating selective and performance enhanced nanodevices. It is an interdisciplinary reference that includes contributing subjects from nanomaterials, biosensors, materials science, biomedical instrumentation and medicinal chemistry. This book is authored by experts in the field of nanomaterial synthesis, modeling, and biosensor applications, and provides insight to readers working in various science fields on the latest advancements in smart and miniaturized nanodevices. These devices enable convenient real-time diagnosis of diseases at clinics rather than laboratories, and include implantable devices that cause less irritation and have improved functionality. Research in the field of nanomaterials is growing rapidly, creating a significant impact across different science disciplines and nanotechnology industries. This synthesis and modeling of nanomaterials has led to many technology breakthroughs and applications, especially in medical science. Provides a distinctive platform for the latest trends in the synthesis of smart nanomaterials for nanodevices in disease diagnostics Presents a broad range of advancements and applications of lateral-flow nanostrip for point-of-care applications Examines smart-phone based nanodevices for field-based diagnosis with accurate information Comprises more than 70 figures and illustrations that will help readers visualize and easily understand the role of nanodevices in the field of nanomedicine Serves as an ideal reference for those studying smart nanomaterials, biosensors, and nanodevices for real-time and in-situ clinical diagnosis and drug delivery
Fungal Nanotechnology 2 provides an updated and thorough explanation of the green and sustainable production of metal- and organic-based nanostructures by various fungal species, as well as an investigation of intracellular and extracellular mechanisms, with a particular focus on the applications of fungal nanotechnology in biomedical, environmental, and agri-food sectors. Since FN is still in its infancy, major research should be conducted in this field; plants, animals, and people will all benefit significantly from this, and effective and environmentally acceptable methods should be developed.
