The Target Organ and the Toxic Process
Author: Philip L. Chambers
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 469
ISBN-13: 3642731139
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Author: Philip L. Chambers
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 469
ISBN-13: 3642731139
DOWNLOAD EBOOKAuthor: Daniel Schlenk
Publisher: CRC Press
Published: 2003-09-02
Total Pages: 426
ISBN-13: 0203361407
DOWNLOAD EBOOKAddressing the numerous gaps in current information, Target Organ Toxicology in Marine and Freshwater Teleosts is an essential resource for researchers and professionals in aquatic toxicology and environmental risk assessment. All the chapters are written by researchers who are internationally recognised for their work in mechanistic aspects of aquatic toxicology. Each chapter focuses on a specific target organ or physiological system and describes how various agents disrupt the normal physiological system and processes. This volume is devoted to specific organs with coverage of the gill, kidney, skin, liver and gut. The companion volume, Systems, provides coverage of toxic effects in the central nervous, immune, neurobehavioural and reproductive systems as well as describing general mechanisms of toxicity.
Author: P K Gupta
Publisher: Springer Nature
Published: 2020-10-19
Total Pages: 338
ISBN-13: 3030504093
DOWNLOAD EBOOKThe book provides easy-to-understand diverse specialized topics in toxicology using self- study questions and answers. The answers are in the form of text along with custom made diagrams and explanations that help the student audience to understand and grasp the matter easily. It is written specifically as a study guide for the toxicology board and other examinations.
Author: Philip C. Burcham
Publisher: Springer Science & Business Media
Published: 2013-11-19
Total Pages: 338
ISBN-13: 144715553X
DOWNLOAD EBOOKThis book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960’s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text.
Author: Gerald M. Cohen
Publisher: CRC Press
Published: 2019-07-17
Total Pages: 340
ISBN-13: 1000697274
DOWNLOAD EBOOKFirst published in 1986: The purpose of these volumes is to provide a valuable reference for established investigators and postgraduate students in toxicology.
Author: Cohen
Publisher: CRC Press
Published: 1986-08-31
Total Pages: 246
ISBN-13: 9780849357756
DOWNLOAD EBOOKThis two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.
Author: Gerald M. Cohen
Publisher: CRC Press
Published: 2020-01-29
Total Pages: 246
ISBN-13: 1000722368
DOWNLOAD EBOOKThis two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.
Author: National Research Council
Publisher: National Academies Press
Published: 1991-02-01
Total Pages: 224
ISBN-13: 0309044375
DOWNLOAD EBOOKThe National Human Monitoring Program (NHMP) identifies concentrations of specific chemicals in human tissues, including toxicologic testing and risk assessment determinations. This volume evaluates the current activities of the NHMP; identifies important scientific, technical, and programmatic issues; and makes recommendations regarding the design of the program and use of its products.
Author: William Hughes
Publisher: CRC Press
Published: 2003-09-02
Total Pages: 189
ISBN-13: 0203362799
DOWNLOAD EBOOKThis introductory text addresses the principles and mechanisms of toxicology as applied to environmentally-encountered toxic agents. Each chapter concludes with review questions that may be used for student self-testing and topics covered include dose response, hazards and risk assessment, determination of toxicity, pesticides, metals, plastics, organic solvents, environmental carcinogens, teratogens and mutagens.
Author: Cohen, James Rab
Publisher: CRC Press
Published: 1999-01-01
Total Pages: 246
ISBN-13: 9780849357695
DOWNLOAD EBOOKThis two-volume set provides essential information on the general principles of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modification and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharmacologists, biochemists, and environmental toxicologists.