The Role of Heat Shock Proteins in Reproductive System Development and Function
The Role of Heat Shock Proteins in Reproductive System Development and Function

Author: Daniel J. MacPhee

Publisher: Springer

Published: 2017-04-07

Total Pages: 160

ISBN-13: 3319514091

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Due to the paucity of reviews on this subject, this volume aims to be timely and promote additional basic and translational research on these proteins in reproductive system development and function within the fields of Anatomy, Embryology and Cell Biology. The breadth of the work being conducted within Reproduction is exemplified by the contributors to this series who will provide reviews on: Grp78 roles in female reproduction, small heat shock proteins/co-chaperones as players in uterine smooth muscle function, the role of heat shock proteins in sperm function and maternal contribution to oogenesis and early embryogenesis, heat shock factors and testes development, HSP90 in ovarian biology and pathology, and the role of HSP70 in regulation of autophagy in pregnancy and parturition.

The Big Book on Small Heat Shock Proteins
The Big Book on Small Heat Shock Proteins

Author: Robert M. Tanguay

Publisher: Springer

Published: 2015-06-15

Total Pages: 603

ISBN-13: 331916077X

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Based upon a workshop entitled “The Small HSP World” held in Québec 2-5 October 2014. Twenty-five scientists provided chapters for the book. The chapters are from the best scientists currently working in this field. These colleagues include Arrigo, Benesch, Benjamin, Buchner-Haslbeck-Weinkauf, Benndorf, Boelens, Carra, Chang, Currie, Ecroyd, Emanuelsson, Fu, Garrido, Golenhofen, Gusev, Hightower, Kampinga, Lavoie, MacRae, Quinlan, Tanguay, Vierling, Vigh, Weeks and Wu. Briefly, the book starts with the structure of small heat shock proteins, moving to their functions and finishing with their involvement in diseases. Although this is quite broad, the structural aspect will be the unifying theme of the book.

Heat Shock Proteins in Cancer
Heat Shock Proteins in Cancer

Author: Stuart K. Calderwood

Publisher: Springer Science & Business Media

Published: 2007-09-09

Total Pages: 399

ISBN-13: 1402064012

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Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.

Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks
Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks

Author: Peter Csermely

Publisher: Springer Science & Business Media

Published: 2007-08-09

Total Pages: 218

ISBN-13: 0387399755

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This book makes a novel synthesis of the molecular aspects of the stress response and long term adaptation processes with the system biology approach of biological networks. Authored by an exciting mixture of top experts and young rising stars, it provides a comprehensive summary of the field and identifies future trends.

Heat Stress Tolerance in Plants
Heat Stress Tolerance in Plants

Author: Shabir H. Wani

Publisher: John Wiley & Sons

Published: 2020-04-06

Total Pages: 315

ISBN-13: 1119432367

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Demystifies the genetic, biochemical, physiological, and molecular mechanisms underlying heat stress tolerance in plants Heat stress—when high temperatures cause irreversible damage to plant function or development—severely impairs the growth and yield of agriculturally important crops. As the global population mounts and temperatures continue to rise, it is crucial to understand the biochemical, physiological, and molecular mechanisms of thermotolerance to develop ‘climate-smart’ crops. Heat Stress Tolerance in Plants provides a holistic, cross-disciplinary survey of the latest science in this important field. Presenting contributions from an international team of plant scientists and researchers, this text examines heat stress, its impact on crop plants, and various mechanisms to modulate tolerance levels. Topics include recent advances in molecular genetic approaches to increasing heat tolerance, the potential role of biochemical and molecular markers in screening germplasm for thermotolerance, and the use of next-generation sequencing to unravel the novel genes associated with defense and metabolite pathways. This insightful book: Places contemporary research on heat stress in plants within the context of global climate change and population growth Includes diverse analyses from physiological, biochemical, molecular, and genetic perspectives Explores various approaches to increasing heat tolerance in crops of high commercial value, such as cotton Discusses the applications of plant genomics in the development of thermotolerant ‘designer crops’ An important contribution to the field, Heat Stress Tolerance in Plants is an invaluable resource for scientists, academics, students, and researchers working in fields of pulse crop biochemistry, physiology, genetics, breeding, and biotechnology.

Heat Shock Proteins in Inflammatory Diseases
Heat Shock Proteins in Inflammatory Diseases

Author: Alexzander A. A. Asea

Publisher: Springer Nature

Published: 2021-10-13

Total Pages: 520

ISBN-13: 3030851680

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The book Heat Shock Proteins in Inflammatory Diseases provides the most comprehensive highlight and insight of the expression, function and therapeutic activity of Heat Shock Proteins in inflammatory diseases including sepsis, psoriasis, neurodegenerative diseases, cancers, viral infection and autoimmune rheumatic diseases. Using an integrative approach, the contributors provide a synopsis of the most current updates on the state of HSP in inflammatory diseases. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.

Heat Shock Proteins and Plants
Heat Shock Proteins and Plants

Author: Alexzander A. A. Asea

Publisher: Springer

Published: 2016-11-23

Total Pages: 341

ISBN-13: 3319463403

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Heat Shock Proteins and Plants provides the most up-to-date and concise reviews and progress on the role of heat shock proteins in plant biology, structure and function and is subdivided into chapters focused on Small Plant HSPs (Part I), Larger Plant HSPs (Part II) and HSPs for Therapeutic Gain (Part III). This book is written by eminent leaders and experts from around the world and is an important reference book and a must-read for undergraduate, postgraduate students and researchers in the fields of Agriculture, Botany, Crop Research, Plant Genetics and Biochemistry, Biotechnology, Drug Development and Pharmaceutical Sciences.

Sustainable Agriculture in the Era of Climate Change
Sustainable Agriculture in the Era of Climate Change

Author: Rajib Roychowdhury

Publisher: Springer Nature

Published: 2020-07-06

Total Pages: 696

ISBN-13: 3030456692

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Under ongoing climate changes, natural and cultivated habitats of major crops are being continuously disturbed. Such conditions impose and exacerbate abiotic and biotic stressors. Drought, salinity, flood, cold, heat, heavy metals, metalloids, oxidants, irradiation, etc. are important abiotic stressors, while diseases and infections caused by plant pathogens, such as fungal agents, bacteria and viruses, are major biotic stresses. In many instances, stresses have become the major limiting factor for agricultural productivity and exert detrimental role on growth and yield of the crops. To help feed an ever increasing world population and to ensure global food security, concerted efforts from scientists and researchers have identified strategies to manage and mitigate the impacts of climate-induced stresses. This book, summarizing their findings, is aimed at crop improvement beyond such kind of barriers, by agronomic practices (genetics, breeding, phenotyping, etc.) and biotechnological applications, including molecular markers, QTL mapping, genetic engineering, transgenesis, tissue culture, various 'omics' technologies and gene editing. It will cover a wide range of topics under environmental challenges, agronomy and agriculture processes, and biotechnological approaches. Additionally, fundamental mechanisms and applied information on stress responses and tolerance will be discussed. This book highlights problems and offers proper solutions for crop stress management with recent information and up-to-date citations. We believe this book is suitable for scientists, researchers and students working in the fields of agriculture, plant science, environmental biology and biotechnology.

Immune Surveillance
Immune Surveillance

Author: Richard T. Smith

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 553

ISBN-13: 0323146260

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Immune Surveillance deals with the issues regarding tumor immunology and surveillance, in which the central theme is all about the life span of the mammalian host that is depleted by the environment with mutagenic agents and solutions. The book is divided into six chapters. It includes discussions on the organization and modulation of cell membrane receptors, as well as the origin and expression of membrane antigens. It also covers the topics on the triggering mechanisms for and effector mechanisms activated by the cellular recognition. These topics analyze and evaluate alternatives for the recognition and destruction mechanisms in the knowledge of cell cooperation and requirements for immune recognition. A chapter provides discourse on a solution for the paradox of thriving tumors based on the demonstrable in vitro host immunity. Another discusses the generation of antibody diversity and the theory of self-tolerance. The last chapter explains the evaluation of the evidence for immune surveillance. This reference will be invaluable to those who specialize in immunology.