Pathology of Laboratory Animals

Pathology of Laboratory Animals

Author: Kurt Benirschke

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 1616

ISBN-13: 146129942X

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Laboratory Animal Medicine has made enor We deeply appreciate the efforts of each of the mous strides in the 47 years since R. Jaffe published authors and co-authors of the 23 chapters in this his "Anatomy and Pathology of Spontaneous Dis two volume work. In some instances the reader will eases of Small Laboratory Animals" in 1931. So note what appears to be repetition in certain chap ters. This repetition was allowed to stand in some much new information had accumulated that in a cases because different approaches seemed useful, new edition in 1958, Jaffe, aided by Cohrs and Meessen, needed the assistance of 46 colleagues to although efforts were made to delete most of the do the subject justice. Like its predecessor, this two redundancy which inevitably arises in a venture of volume comprehensive treatise on "Pathologie der this kind. We will be grateful if our colleagues point out errors and send us specific and general Laboratoriumstiere" was written in German and criticism of this work to allow corrections in the thus not readily available to the widening circle of event of reprinting or a next edition. veterinarians and pathologists who now are inter One objective has been to assemble current in ested in laboratory animals. Aside from the need to have a comprehensive formation in the pathologic aspects of diseases of review of laboratory animal pathology in English, laboratory animals.


Developmental and Reproductive Toxicology

Developmental and Reproductive Toxicology

Author: Ronald D. Hood

Publisher: CRC Press

Published: 2005-08-30

Total Pages: 1164

ISBN-13: 1420040545

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Completely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers e


Atherogenesis and Aging

Atherogenesis and Aging

Author: Sandra R. Bates

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 211

ISBN-13: 1461246520

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Age is a nonreversible risk factor for atherosclerosis. The atherosclerotic process begins early in life, progresses during the middle years, and usually culminates in clinical disease towards the later years of the life span. Since atherosclerosis is a multifactorial disease, and many of the "risk factors" are time- and age related, it has been difficult to sort out intrinsic aging from environmental factors that operate over many years. Furthermore, the role of genetic factors remains unknown. This workshop has produced much worthwhile information that is helping elucidate the impact of age on atherogenesis. Important strides have been made in understanding the role of changes in the arterial wall and of lipoproteins, platelets, and monocyte-derived macrophages in the disease process. In parallel, our understanding of the biology of aging has increased sufficiently so that these two areas of interest can now profitably intersect. The proceedings of this successful workshop emphasize that there is much to be gained by continued interaction between those scientists interested in the biology of aging at all levels and those interested in the atherosclerotic process. Hopefully, we may eventually progress in our understanding and reach the stage when atherosclerosis will no longer be an inexorable concomitant of human aging. Edwin L. Bierman, M. D. Contents Foreword V Contributors IX Participants in the Workshop XV Introduction and Statement of Research Recommendations Sandra R.


Spontaneous Pathology of the Laboratory Non-human Primate

Spontaneous Pathology of the Laboratory Non-human Primate

Author: Alys Bradley

Publisher: Academic Press

Published: 2023-06-20

Total Pages: 628

ISBN-13: 012813089X

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Spontaneous Pathology of the Laboratory Non-human Primate serves as a "go to" resource for all pathologists working on primates in safety assessment studies. In addition, it helps diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathologies when assigning cause of death to species in zoological collections. Primate species included are rhesus, cynomolgus macaques and marmosets. Multi-authored chapters are arranged by organ system, thus providing the necessary information for continued research.Pathologists often face a lack of suitable reference materials or historical data to determine if pathologic changes they are observing in monkeys are spontaneous or a consequence of other treatments or factors. - Contains color illustrations that depict the most common lesions to augment descriptions - Covers descriptions that are compliant with the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) guidelines set forth by the Society of Toxicologic Pathology (STP) - Provides pathologists with common terms that are compliant with the FDA's Standard for Exchange of Nonclinical Data (SEND) guidelines


The Rhesus Monkey

The Rhesus Monkey

Author: Geoffrey Bourne

Publisher: Elsevier

Published: 2014-07-23

Total Pages: 453

ISBN-13: 0323161715

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The Rhesus Monkey discusses the use of the rhesus monkey as a test subject in biomedical research. This text provides information that is essential for research that involves the rhesus monkey, from conditioning a wild rhesus monkey to restoring it to its natural state after the tests that it is subjected to. This book covers the phases a rhesus monkey specimen will go through in an experiment. Each chapter covers different facets of using a rhesus monkey as a test subject, including selecting a suitable specimen, conditioning, medication, nourishment, breeding, and pathological threats. Researchers in all fields will find this book an invaluable source of information regarding the best use of rhesus monkeys as research subjects.


The Laboratory Primate

The Laboratory Primate

Author:

Publisher: Elsevier

Published: 2005-09-19

Total Pages: 639

ISBN-13: 008045416X

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A volume in the Handbook of Experimental Animals series, The Laboratory Primate details the past and present use of primates in biomedical research, and the husbandry, nutritional requirements, behaviour, and breeding of each of the commonly used species. Practical information on regulatory requirements, not available in other texts, is covered. Sections on experimental models cover the major areas of biomedical research, including AIDS, cancer, neurobiology and gene therapy. Assisted reproductive technology, tissue typing, and minimum group sizes for infectious disease/vaccine studies are also included. - Two-color, user-friendly format, with copious illustrations and color plates - Includes detailed, well-illustrated sections on gross & microscopic anatomy, common diseases, and special procedures, including surgical techniques


Laboratory Animal Medicine

Laboratory Animal Medicine

Author: James G. Fox

Publisher: Academic Press

Published: 2013-10-02

Total Pages: 769

ISBN-13: 1483269167

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Laboratory Animal Medicine is a compilation of papers that deals with the diseases and biology of major species of animals used in medical research. The book discusses animal medicine, experimental methods and techniques, design and management of animal facilities, and legislation on laboratory animals. Several papers discuss the biology and diseases of mice, hamsters, guinea pigs, and rabbits. Another paper addresses the dog and cat as laboratory animals, including sourcing of these animals, housing, feeding, and their nutritional needs, as well as breeding and colony management. The book also describes ungulates as laboratory animals, including topics on sourcing, husbandry, preventive medical treatments, and housing facilities. One paper addresses primates as test animals, covering the biology and diseases of old world primates, Cebidae, and ferrets. Some papers pertain to the treatment, diseases, and needed facilities for birds, amphibians, and fish. Other papers then deal with techniques of experimentation, anesthesia, euthanasia, and some factors (spontaneous diseases) that complicate animal research. The text can prove helpful for scientists, clinical assistants, and researchers whose work involves laboratory animals.


Anatomy and Physiology

Anatomy and Physiology

Author: Geoffrey Bourne

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 437

ISBN-13: 0323150365

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The Rhesus Monkey, Volume I: Anatomy and Physiology discusses the anatomic and physiological measurement, microscopic anatomy, learning, skills, general behavior, and vocalization of rhesus monkey. The rhesus monkey (Macaca mulatta) is widely used for biomedical and psychological studies. Accordingly, an enormous fund of scientific information is available in papers and some collected data. This book is generally a collection of data from over 2000 papers on rhesus monkey. It covers topics on the cerebral angiography, electrocardiogram, and vector cardiogram of the rhesus monkey. It also provides additional information on morphology and function of rhesus kidney; the development and eruption of teeth in rhesus; and the histology and histochemistry of the rhesus monkey. This book serves as an invaluable reference work for all who work with this primate.