Placebo responses are automatic and unconscious and cannot be predicted on conscious volition. Instead, they reflect complex interactions between the innate reward system of the nervous system and encoded procedural memories and imaginal fantasies. This book contributes therapeutic effects, varies in potency, and exhibits its own pathologies.
National Geographic's riveting narrative explores the world of placebos, hypnosis, false memories, and neurology to reveal the groundbreaking science of our suggestible minds. Could the secrets to personal health lie within our own brains? Journalist Erik Vance explores the surprising ways our expectations and beliefs influence our bodily responses to pain, disease, and everyday events. Drawing on centuries of research and interviews with leading experts in the field, Vance takes us on a fascinating adventure from Harvard's research labs to a witch doctor's office in Catemaco, Mexico, to an alternative medicine school near Beijing (often called "China's Hogwarts"). Vance's firsthand dispatches will change the way you think--and feel. Expectations, beliefs, and self-deception can actively change our bodies and minds. Vance builds a case for our "internal pharmacy"--the very real chemical reactions our brains produce when we think we are experiencing pain or healing, actual or perceived. Supporting this idea is centuries of placebo research in a range of forms, from sugar pills to shock waves; studies of alternative medicine techniques heralded and condemned in different parts of the world (think crystals and chakras); and most recently, major advances in brain mapping technology. Thanks to this technology, we're learning how we might leverage our suggestibility (or lack thereof) for personalized medicine, and Vance brings us to the front lines of such study.
The biological power of the placebo effect. The power of placebos to ameliorate symptoms has been with us for centuries. Western medicine today is finding it increasingly difficult to ignore the efficacy of placebos. In some clinical trials with placebos as controls, inert or sham replicas of active pharmaceutical drugs and even sham surgeries have been found to be as beneficial as the intervention being tested. In this volume in the MIT Press Essential Knowledge series, Kathryn Hall examines the power of placebos, showing how their effects can influence our clinical trials, clinical encounters and, collectively, Hall argues, our public health. Hall, who has studied the placebo effect for years, reviews the history of the placebo in medicine, tracing its evolution from quackery and patent medicine to its use as a control in clinical trials. She considers the ways that expectations and learning affect our response to placebos; advances in neuroimaging that reveal the inner workings of the placebo effect; the “nocebo” effect; placebo controls in randomized clinical trials; and the use of psychological profiles and genetics to predict individual placebo response. The effects of placebos have been hiding in plain sight; with this book, Hall helps bring them into clearer view.
The Placebo Effect in Clinical Practice brings together what we know about the mechanisms behind the placebo response, as well as the procedures that promote these responses, in order to provide a focused and concise overview on how current knowledge can be applied in treatment settings.
Psychodynamic psychotherapy and psychoanalysis have had to defend themselves from a barrage of criticisms throughout their history. In this book David Jopling argues that the changes achieved through therapy are really just functions of placebos that rally the mind's native healing powers. It is a bold new work that delivers yet another blow to Freud and his followers.
Beginning with a review of the role of placebos in the history of medicine, this book investigates the current surge of interest in placebos, and probes the methodological difficulties of saying scientifically just what placebos can and cannot do.
Ranging from antiquity to modern times, this history of the placebo effect is especially timely in light of renewed interest in the mind-body relationship. Until this century, most medications prescribed by physicians were pharmacologically inert, if not harmful. That is, physicians were prescribing placebos or worse without knowing it. In a sense, then, the history of medical treatment until relatively recently is the history of the placebo effect. Based on the authors' lifelong study and clinical research, this is a comprehensive and scholarly examination of the placebo effect. The authors begin by surveying the use of placebos from antiquity to modern times. They also examine the development, use, and validity of the double-blind, controlled clinical trial. And they present their own study of the placebo effect in more than 1000 patients. Demonstrating both the magnitude and the limitations of the placebo effect, the book helps to clarify knotty issues ranging from the evaluation of therapies to the ethics of conducting controlled studies in which patients are deliberately given placebos. With the renewed interest in the mind-body relationship as well as in the role of placebos in new and alternative medical procedures and therapies, the findings of this book are especially timely.
THE NEW YORK TIMES BESTSELLER SHORTLISTED FOR THE ROYAL SOCIETY SCIENCE BOOK PRIZE LONGLISTED FOR THE WELLCOME PRIZE ALL IN THE MIND? - Can meditation fend off dementia? - Can the smell of lavender affect the immune system? - Can your thoughts ease physical pain? In Cure, award-winning science writer Jo Marchant travels the world to meet the physicians, patients and researchers on the cutting edge of mind-body medicine, asking how the brain can heal the body and how we can all make changes to keep ourselves healthier.
The history, philosophy, ethics, and science behind the placebo and nocebo effects. Placebos are the most widely used treatments in the history of medicine. Thousands of studies show that they can be effective and make us happier and healthier. Yet confusion about what placebos are and how to measure their effects prevents some doctors from using them to help patients. Meanwhile, damage caused by the nocebo effect—the negative effect of expecting something bad—is not widely recognized. In The Power of Placebos, Jeremy Howick provides an interdisciplinary perspective on placebos and nocebos based on more than twenty years of research and data from over 300,000 patients. This book, the culmination of that research, offers practical ways for researchers, policymakers, and doctors to put placebo and nocebo research into practice to improve health outcomes. In addition to providing an overview of placebos and nocebos and explaining how belief systems and context can create physiological effects in the body, Howick advocates for a number of controversial positions, including why it may be unethical to include placebos in most clinical trials in which there are already established therapies and why physicians should consider using placebos regularly in their practices. Howick also underscores the importance of the therapeutic effects of interactions between health care practitioners and patients, in the context of care. The Power of Placebos dispels the confusion surrounding placebos and paves the way for doctors to help patients by enhancing placebo effects and avoiding the pitfalls of nocebos.
