Intrigued as much by its complex nature as by its outsider status in traditional organic chemistry, the editors of The Organic Chemistry of Sugars compile a groundbreaking resource in carbohydrate chemistry that illustrates the ease at which sugars can be manipulated in a variety of organic reactions. Each chapter contains numerous examples demonst
The report describes work in progress in the Organic Chemistry Section at the National Bureau of Standards on the following subjects: Synthesis of carbon-14- and tritium-labeled carbohydrates, isotope dilution and double-lavel methods of analysis, determination of kinetic isotope effects, use of solvent isotope-effects for studying pyranose-furanose interconversions, measurements of rates of primary enolization, rates of rearrangement of one sugar to another by bases, estimation of the relative stabilities of isomeric hexoses, reversible aldol condensations, mechanism for the formation of saccharinic acids, formation of branchedchain aldoses and linear ketoses by aldol condensations, stereochemistry of monoaminotetrahydroxycyclopentane derivatives, cyclic polyhydroxy ketones, phenylhydrazonophenylazo tautomerism, acetamido-deoxyketoses, syntheses and properties of selected organic compounds, interaction of aromatic hydrocarbons with oxygen, oxidation of polycyclic, aromatic hydrocarbons on particulate matter, loss on filtration of aqueous solutions of polycyclic, aromatic hydrocarbons, oxidation products of pyrene, and preparation of 1-phenyl-1,3-butanedione chelates of chromium and iron for use as new metallo-organic standards. (Author).
Carbohydrate Chemistry provides review coverage of all publications relevant to the chemistry of monosaccharides and oligosaccharides in a given year. The amount of research in this field appearing in the organic chemical literature is increasing because of the enhanced importance of the subject, especially in areas of medicinal chemistry and biology. In no part of the field is this more apparent than in the synthesis of oligosaccharides required by scientists working in glycobiology. Clycomedicinal chemistry and its reliance on carbohydrate synthesis is now very well established, for example, by the preparation of specific carbohydrate- based antigens, especially cancer-specific oligosaccharides and glycoconjugates. Coverage of topics such as nucleosides, amino-sugars, alditols and cyclitols also covers much research of relevance to biological and medicinal chemistry. Each volume of the series brings together references to all published work in given areas of the subject and serves as a comprehensive database for the active research chemist Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.
Detailing commonly used methods and procedures, this reference discusses the reactions and derivative forms of carbohydrates. Preparative Carbohydrate Chemistry covers the formation, cleavage, and reactions of derivatives and illustrates bond-forming reactions of SN2 types, free radicals, chain extensions, and branching. The contents include: sugar derivatives; selected reactions in carbohydrate chemistry; chemical synthesis of oligosaccharides and O-and N -glycosyl compounds; enzymatic synthesis of sialic acid, KDO, and related deoxyulosonic acids, and of oligosaccharides; synthesis of -glycosyl compounds; carbocycles from carbohydrates; and total synthesis of sugars from non-sugars. This authoritative reference offers relevant chapters on reactions and derivative forms of carbohydrates, including commonly used methods as well as new experimental procedures. It also contains insightful chapter commentaries and succinct topic histories.
