The Neuroimmunological Basis of Behavior and Mental Disorders

The Neuroimmunological Basis of Behavior and Mental Disorders

Author: Allan Siegel

Publisher: Springer Science & Business Media

Published: 2008-11-09

Total Pages: 437

ISBN-13: 0387848517

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For many years, the immune and central nervous systems were thought to function independently with little or no interaction between the two. This view has und- gone dramatic changes over the past three decades. Indeed, we now know that there exists various feedback loops between the brain and immune systems that impact signi cantly upon different behavioral processes, including normal behavior and mental disorders. Pioneering efforts in generating this change were initiated by a number of early investigators. Included were those whose efforts were directed at establishing neuroimmune connections as well as others whose research focused upon the relationship between immunity, cytokines, and behavior. This book brings together outstanding scientists and clinicians who have made major contributions to the rapidly developing eld investigating the relationship between immunity and behavior. The book is divided into three parts. The rst part describes pathways by which the brain and immune systems communicate and int- act with each other. In the chapter “Cytokines and the Blood–Brain Barrier” p- vides insight into interactions between the blood–brain barrier and cytokines. Such interactions underlie basic communication between the immune system and brain that are present in normal as well as in disease conditions. In the chapter “Neu- chemical and Endocrine Responses to Immune Activation: The Role of Cytokines,” the neurochemical and endocrine consequences of immune challenge and cytokine administration on central neurotransmitter activity are discussed.


The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide

Author: Yogesh Dwivedi

Publisher: CRC Press

Published: 2012-06-25

Total Pages: 485

ISBN-13: 143983881X

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With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.


Introduction to Psychoneuroimmunology

Introduction to Psychoneuroimmunology

Author: Jorge H. Daruna

Publisher: Academic Press

Published: 2012-02-24

Total Pages: 336

ISBN-13: 0123820499

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Health is maintained by the coordinated operation of all the biological systems that make up the individual. The Introduction to Psychoneuroimmunology, Second Edition, presents an overview of what has been discovered by scientists regarding how bodily systems respond to environmental challenges and intercommunicate to sustain health. The book touches on the main findings from the current literature without being overly technical and complex. The result is a comprehensive overview of psychoneuroimmunology, which avoids oversimplification, but does not overwhelm the reader. Single authored for consistency of breadth and depth, with no redundancy of coverage between chapters Covers endocrine-immune modulation, neuro-immune modulation, and the enhancing or inhibiting processes of one or more systems on the others Expanded use of figures, tables, and text boxes


Neuroscience in the 21st Century

Neuroscience in the 21st Century

Author: Donald W. Pfaff

Publisher: Springer Nature

Published: 2022-10-17

Total Pages: 4592

ISBN-13: 3030888320

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Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its third edition serves as a comprehensive resource to students and researchers alike.


Motivation

Motivation

Author: Lambert Deckers

Publisher: Routledge

Published: 2022-03-30

Total Pages: 451

ISBN-13: 100045343X

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Motivation provides an accessible introduction to motivation and emotion, combining classic studies with current research and uses numerous real-world examples to engage the student and make, often difficult, theoretical concepts come to life. By understanding and applying the principles of motivation described in the text, students will not only discover insights into what motivates their own behavior but also how to instigate self-change through goal-setting. Throughout the book the author adopts an evolutionary approach to explore the effect of interpersonal relationships, food preferences, fear, music, and the emotions on motivation, at the same time considering how personality traits and psychological needs are essential for understanding why people are motivated by different things. The motivation of compulsive behavior from addictions, such as drugs, gambling, Internet gaming, and obsessive exercise is also considered, providing a truly comprehensive overview of biological, psychological, and environmental sources of motivation. The sixth edition has been thoroughly updated throughout and is accompanied by an instructor’s manual that contains multiple choice questions, essay questions with answers, websites related to motivation and emotion, power point slides, in-class activities, and discussion questions. It is an essential read for all students of motivation.


Biomarkers of Neurological and Psychiatric Disease

Biomarkers of Neurological and Psychiatric Disease

Author:

Publisher: Academic Press

Published: 2011-10-29

Total Pages: 471

ISBN-13: 0123877237

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Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. - Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist


Your Vitamins are Obsolete: The Vitamer Revolution: A Program for Healthy Living and Healthy Longevity

Your Vitamins are Obsolete: The Vitamer Revolution: A Program for Healthy Living and Healthy Longevity

Author: Sheldon Zablow, M.D.

Publisher: Hybrid Global Publishing

Published: 2021-05-21

Total Pages: 250

ISBN-13: 1948181878

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Did you know the synthetic B-vitamins found in supplements cannot be absorbed well or easily converted into the bioactive forms our cells use? Even other vitamins can’t work well if there is not enough of the naturally occurring B forms called vitamers. For example, without B vitamers, taking vitamin D won't prevent osteoporosis. Learn how the naturally occurring vitamers DO work and why, and start on your pathway to healthy living and longevity today!


Handbook of Computational Neurodegeneration

Handbook of Computational Neurodegeneration

Author: Panagiotis Vlamos

Publisher: Springer Nature

Published: 2023-07-25

Total Pages: 1031

ISBN-13: 3319759221

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The Handbook of Computational Neurodegeneration provides a comprehensive overview of the field and thus bridges the gap between standard textbooks of research on neurodegeneration and dispersed publications for specialists that have a narrowed focus on computational methods to study this complicated process. The handbook reviews the central issues and methodological approaches related to the field for which the reader pursues a thorough overview. It also conveys more advanced knowledge, thus serving both as an introductory text and as a starting point for an in-depth study of a specific area, as well as a quick reference source for the expert by reflecting the state of the art and future prospects. The book includes topics that are usually missing in standard textbooks and that are only marginally represented in the specific literature. The broad scope of this handbook is reflected by five major parts that facilitate an integration of computational concepts, methods and applications in the study of neurodegeneration. Each part is intended to stand on its own, giving an overview of the topic and the most important problems and approaches, which are supported by examples, practical applications, and proposed methodologies. The basic concepts and knowledge, standard procedures and methods are presented, as well as recent advances and new perspectives.


The Immunology of the Cat

The Immunology of the Cat

Author: Ian R Tizard

Publisher: Elsevier

Published: 2024-09-01

Total Pages: 466

ISBN-13: 0443291799

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The Immunology of the Cat makes available the first single-source, comprehensive review of the feline immune system, reporting on all immunologic aspects of diseases of the cat and its relatives and relating recent basic science to important clinical issues. The book opens with the evolution, domestication, and development of the cat then provides detailed information on immunity to infectious diseases, feline allergic diseases, the top feline autoimmune diseases, and feline immunodeficiencies. Content examines feline vaccines, hypersensitivity, cancer, nutrition, and the aged cat. Professionals in veterinary research and practice will appreciate complete information on all aspects of feline immunology in one essential resource. - Introduces the first comprehensive review of feline immunology - Links recent basic science to important clinical issues - Provides detailed and current information in one resource