The NeuroCOVID-19 Syndrome: Cognitive and Psychological Profiles, Physiopathology, and Impact on Neurologically Vulnerable Populations
The NeuroCOVID-19 Syndrome: Cognitive and Psychological Profiles, Physiopathology, and Impact on Neurologically Vulnerable Populations

Author: Ludivine Chamard-Witkowski

Publisher: Frontiers Media SA

Published: 2024-08-16

Total Pages: 103

ISBN-13: 2832552447

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The Coronavirus Disease 2019 (COVID-19) global pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to the identification of a broad range of post-acute Covid neurological symptoms including cognitive impairments, specific executive dysfunctions with sensorimotor deficits (paresthesia, numbness, or weakness of specific body parts), changes in sleep, changes in taste or smell, hallucinations, emotional distress (anxiety, depression), and fatigue/asthenia. Alarmingly, those post-acute sequelae of COVID-19 (PASC) can occur several weeks after infection, arise after severe, mild, or even asymptomatic SARS-CoV2 infection, and are characterized by the persistence, worsening, or new onset of chronic and debilitating neurological symptoms, which have led to the use of NeuroCOVID syndrome terminology. A link between COVID-19-related neurological symptoms and other neurological diseases has not been clearly established, but an increasing number of studies report an increase in mortality post-SARS-CoV-2 infection and an atypical clinical presentation of COVID-19 in patients with dementia. Another intriguing discovery is that survivors that did not suffer from neurodegenerative diseases before the COVID-19 infection seem to be at high risk for subsequent development of neurological disease and in particular Alzheimer’s disease, and to develop early-dementia symptoms. However, the pathophysiology of those associations is not yet delineated, and more research is needed on NeuroCOVID in both the general population and in specific subgroups affected by neurological disorders. As the COVID-19 pandemic could cause a significant rise in the number of dementia patients in the long term, there is an urgent need to understand how PASC is associated with neurodegenerative disorders or with a worsening of neurologic symptoms in neurologically vulnerable populations.

Neuroimmune Pharmacology
Neuroimmune Pharmacology

Author: Tsuneya Ikezu

Publisher: Springer

Published: 2016-12-22

Total Pages: 1045

ISBN-13: 3319440225

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The second edition of Neuroimmune Pharmacology bridges the disciplines of neuroscience, immunology and pharmacology from the molecular to clinical levels with particular thought made to engage new research directives and clinical modalities. Bringing together the foremost field authorities from around the world, Neuroimmune Pharmacology will serve as an invaluable resource for the basic and applied scientists of the current decade and beyond.

WAIS-IV, WMS-IV, and ACS
WAIS-IV, WMS-IV, and ACS

Author: James A. Holdnack

Publisher: Academic Press

Published: 2013-06-20

Total Pages: 623

ISBN-13: 0123869536

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This book provides users of the Wechsler Adult Intelligence Scale (WAIS-IV) with information on applying the WAIS-IV, including additional indexes and information regarding use in special populations for advanced clinical use and interpretation. The book offers sophisticated users of the WAIS-IV and Wechsler Memory Scale (WMS-IV) guidelines on how to enhance the clinical applicability of these tests. The first section of the book provides an overview of the WAIS-IV, WMS-IV, and new Advanced Clinical Solutions for Use with the WAIS-IV/WMS-IV (ACS). In this section, examiners will learn: - Normal versus atypical score variability - Low-score prevalence in healthy adults versus clinical populations - Assessing whether poor performance reflects a decline in function or is the result of suboptimal effort New social cognition measures found in the ACS are also presented. The second part focuses on applying the topics in the first section to specific clinical conditions, including recommended protocols for specific clientele (e.g. using demographically adjusted norms when evaluating individuals with brain injury). Common clinical conditions are discussed, including Alzheimer's disease, mild cognitive impairment, traumatic brain injury, and more. Each chapter provides case examples applying all three test batteries and using report examples as they are obtained from the scoring assistant. Finally, the use of the WAIS-IV/WMS-IV and the ACS in forensic settings is presented. - Coverage of administration and scoring of WAIS-IV, WMS-IV and ACS - Information contained on the use of WAIS-IV with special populations - Case studies in each chapter - Written by the creators of WAIS-IV, WMS-IV and ACS

Understanding Coronavirus
Understanding Coronavirus

Author: Raul Rabadan

Publisher: Cambridge University Press

Published: 2021-10-14

Total Pages: 167

ISBN-13: 1009086650

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Since the identification of the first cases of the coronavirus in December 2019, there has been a significant amount of confusion regarding the origin and spread of the so-called 'coronavirus', SARS-CoV-2, and the cause of the disease COVID-19. Conflicting messages from the media and officials across different countries and organizations, the abundance of disparate sources of information, unfounded conspiracy theories on the origins of the virus, unproven therapies, and inconsistent public health measures, have all served to increase anxiety in the population. Where did the virus come from? How is it transmitted? How does it cause disease? Is it like flu? What is a pandemic? In this concise and accessible introduction, a leading expert provides answers to these commonly asked questions. This revised and updated edition now also covers how the virus mutates, how important these mutations are, how vaccines work, and what we can expect in the near and long-term future.

Coronavirus Disease - COVID-19
Coronavirus Disease - COVID-19

Author: Nima Rezaei

Publisher: Springer Nature

Published: 2021-05-10

Total Pages: 964

ISBN-13: 3030637611

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In December 2019, the world witnessed the occurrence of a new coronavirus to humanity. The disease spread quickly and became known as a pandemic globally, affecting both society and the health care system, both the elderly and young groups of people, and both the men’s and women’s groups. It was a universal challenge that immediately caused a surge in scientific research. Be a part of a world rising in fighting against the pandemic, the Coronavirus Disease - COVID-19 was depicted in the early days of the pandemic, but updated by more than 200 scientists and clinicians to include many facets of this new infectious pandemic, including i, characteristics, ecology, and evolution of coronaviruses; ii, epidemiology, genetics, and pathogenesis (immune responses and oxidative stress) of the disease; iii, diagnosis, prognosis, and clinical manifestations of the disease in pediatrics, geriatrics, pregnant women, and neonates; iv, challenges of co-occurring the disease with tropical infections, cardiovascular diseases, hypertension, and cancer and to the settings of dentistry, hematology, ophthalmology, and pharmacy; v, transmission, prevention, and potential treatments, ranging from supportive ventilator support and nutrition therapy to potential virus- and host-based therapies, immune-based therapies, photobiomodulation, antiviral photodynamic therapy, and vaccines; vi, the resulting consequences on social lives, mental health, education, tourism industry and economy; and vii, multimodal approaches to solve the problem by bioinformatic methods, innovation and ingenuity, globalization, social and scientific networking, interdisciplinary approaches, and art integration. We are approaching December 2020 and the still presence of COVID-19, asking us to call it COVID (without 19).

Obsessive-Compulsive and Related Disorders
Obsessive-Compulsive and Related Disorders

Author: Samar Reghunandanan

Publisher: OUP Oxford

Published: 2015-06-25

Total Pages: 167

ISBN-13: 019101687X

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Providing clinicians and patients with the latest developments in research, this new edition is a succinct and practical introduction to the diagnosis, evaluation and management of OCD and other related disorders. Part of the Oxford Psychiatry Library series, this pocketbook includes individual chapters on the phenomenology, pathogenesis, pharmacotherapy and psychotherapy of OCD and other related disorders, and features fully updated content and research. The book also includes a helpful resources chapter, and an Appendix with summaries of the major rating scales used to assess patients with OCD, which will be of use to both clinicians and patients. Obsessive-compulsive disorder (OCD) and Obsessive-compulsive-related disorders (OCRDs) are anxiety disorders characterized by obsessions and compulsions, and varying degrees of anxiety and depression. OCRDs are considered to be one of the most disabling of psychiatric disorders and they present a tremendous economic and social burden, both for the affected individual, their family, and for society at large. In contrast to other psychiatric conditions of a comparable or lesser prevalence and patient burden, relatively little is understood about the aetiology, and cognitive effects of OCRDs.

The Madness of Fear
The Madness of Fear

Author: Edward Shorter

Publisher: Oxford University Press

Published: 2018-06-27

Total Pages: 225

ISBN-13: 0190881208

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What are the real disease entities in psychiatry? This is a question that has bedeviled the study of the mind for more than a century yet it is low on the research agenda of psychiatry. Basic science issues such as neuroimaging, neurochemistry, and genetics carry the day instead. There is nothing wrong with basic science research, but before studying the role of brain circuits or cerebral chemistry, shouldn't we be able to specify how the various diseases present clinically? Catatonia is a human behavioral syndrome that for almost a century was buried in the poorly designated psychiatric concept of schizophrenia. Its symptoms are well-know, and some of them are serious. Catatonic patients may die as their temperatures accelerate; they become dehydrated because they refuse to drink; they risk inanition because they refuse to eat or move. Autistic children with catatonia may hit themselves repeatedly in the head. We don't really know what catatonia is, in the sense that we know what pneumonia is. But we can identify it, and it is eminently treatable. Clinicians can make these patients better on a reliable basis. There are few other disease entities in psychiatry of which this is true. So why has there been so little psychiatric interest in catatonia? Why is it simply not on the radar of most clinicians? Catatonia actually occurs in a number of other medical illnesses as well, but it is certainly not on the radar of most internists or emergency physicians. In The Madness of Fear, Drs. Shorter and Fink seek to understand why this "vast field of ignorance" exists. In the history of catatonia, they see a remarkable story about how medicine flounders, and then seems to find its way. And it may help doctors, and the public, to recognize catatonia as one of the core illnesses in psychiatry.

Autoimmune Neurology
Autoimmune Neurology

Author:

Publisher: Elsevier

Published: 2016-03-11

Total Pages: 569

ISBN-13: 0444634460

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Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. - Includes comprehensive coverage of autoimmune neurology - Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders - Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities

Neurotrauma and Critical Care of the Brain
Neurotrauma and Critical Care of the Brain

Author: Jack Jallo

Publisher: Thieme

Published: 2018-04-04

Total Pages: 1124

ISBN-13: 1626233403

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"This book really is a complete primer on the head injured patient. Without a map such as the one this book metaphorically provides, the voyage to mastery can be hazardous for both practitioner and patient."— Journal of the American Medical Association Neurotrauma and Critical Care of the Brain, 2nd edition by renowned neurosurgeons Jack Jallo and Christopher Loftus incorporates salient components of the highly praised first edition. The updated text reflects cutting-edge discussion on traumatic brain injury management in a neurocritical care setting. Contributions from top experts in neurosurgery, neurology, critical care, cardiac and pulmonary care, and trauma surgery provide a concise review of a complex and evolving field. The book lays a solid foundation with discussion of TBI classification, pathophysiology, key blood biomarkers, noninvasive neuromonitoring in severe TBI patients, multimodality monitoring in neurocritical care, and brain imaging modalities. From the prehospital setting to intensive care, top experts share clinical pearls and core guidelines on the management of mild, moderate, and severe TBI and complications. Chapters new to this edition include concomitant injuries, orbital/facial fractures, vascular injuries, spine fractures, autonomic dysfunction, and temperature management. Key Highlights Specialized topics include wartime penetrating injuries, cardiovascular complications of TBI, venous thromboembolism prophylaxis, ethical considerations, TBI costs in the U.S. and the financial return on helmets Management of pediatric brain injuries in the NICU with illustrative cases Nearly 200 high quality illustrations facilitate understanding of complex anatomy and techniques Summary tables provide a handy overview of injury type, causes, characteristics, and recommended imaging modalities This remarkable resource is essential reading for neurosurgeons, neurologists, trauma physicians, critical care and rehabilitation medicine specialists, and residents in these specialties. Paired with Neurotrauma and Critical Care of the Spine, 2nd edition, this dynamic duo is the most up-to-date neurocritical care reference available today.