Recognition and Management of Pesticide Poisonings (5th Ed. )
Recognition and Management of Pesticide Poisonings (5th Ed. )

Author: J. Routt Reigart

Publisher: DIANE Publishing

Published: 2009-06

Total Pages: 238

ISBN-13: 1437914527

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This 5th ed. is an update and expansion of the 1989 4th ed. This EPA manual provides health professionals with information on the health hazards of pesticides currently in use, and current consensus recommendations for management of poisonings and injuries caused by them. As with previous updates, this new ed. incorporates new pesticide products that are not necessarily widely known among health professionals. Contents: (1) General Information: Introduction; General Principles in the Management of Acute Pesticide Poisonings; Environmental and Occupational History; (2) Insecticides; (3) Herbicides; (4) Other Pesticides; (5) Index of Signs and Symptoms; Index of Pesticide Products. Charts and tables.

Microbial Degradation of Xenobiotics
Microbial Degradation of Xenobiotics

Author: Shree Nath Singh

Publisher: Springer Science & Business Media

Published: 2011-10-07

Total Pages: 488

ISBN-13: 3642237894

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Our interest in the microbial biodegradation of xenobiotics has increased many folds in recent years to find out sustainable ways for environmental cleanup. Bioremediation and biotransformation processes harness the naturally occurring ability of microbes to degrade, transform or accumulate a wide range of organic pollutants. Major methodological breakthroughs in recent years through detailed genomic, metagenomic, proteomic, bioinformatic and other high-throughput analyses of environmentally relevant microorganisms have provided us unprecedented insights into key biodegradative pathways and the ability of organisms to adapt to changing environmental conditions. The degradation of a wide spectrum of organic pollutants and wastes discharged into the environment by anthropogenic activities is an emerging need today to promote sustainable development of our society with low environmental impact. Microbial processes play a major role in the removal of recalcitrant compounds taking advantage of the astonishing catabolic versatility of microorganisms to degrade or transform such compounds. New breakthroughs in sequencing, genomics, proteomics, bioinformatics and imaging are generating vital information which opens a new era providing new insights of metabolic and regulatory networks, as well as clues to the evolution of degradation pathways and to the molecular adaptation strategies to changing environmental conditions. Functional genomic and metagenomic approaches are increasing our understanding of the relative importance of different pathways and regulatory networks to carbon flux in particular environments and for particular compounds. New approaches will certainly accelerate the development of bioremediation technologies and biotransformation processes in coming years for natural attenuation of contaminated environments

Toxicology of Organophosphate and Carbamate Compounds
Toxicology of Organophosphate and Carbamate Compounds

Author: Ramesh C Gupta

Publisher: Academic Press

Published: 2011-04-28

Total Pages: 781

ISBN-13: 0080543103

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This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. - Describes everything you need to know about Organophosphates and Carbamates - Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants - Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates - Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases - Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity - Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis - Provides in vitro and in vivo models for neurotoxicity testing - Integrates knowledge of studies in lab animals and humans - Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues - Describes management of Anticholinesterase poisoning in humans

Current Catalog
Current Catalog

Author: National Library of Medicine (U.S.)

Publisher:

Published:

Total Pages: 1378

ISBN-13:

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First multi-year cumulation covers six years: 1965-70.