Nutrition and Gene Expression

Nutrition and Gene Expression

Author: Carolyn D. Berdanier

Publisher: CRC Press

Published: 1992-12-15

Total Pages: 600

ISBN-13: 9780849369612

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Nutrition and Gene Expression is devoted to exploring the tissue-specific and developmental aspects of the interaction between nutrients and the genome. The book discusses chemical sensitivity in relation to the ability of cells to detect nutrients; reviews the means by which lower organisms respond to nutrients; and provides examples on how each of the classes of nutrients affects genetic transcription, mRNA translation or stability. The receptor-mediated actions of vitamin D and retinoic acid on gene expression are discussed, including the case of bone formation and dissolution. Other important topics covered in the volume include newly discovered effects of fatty acids on regulating gene expression, the effects of diet on mRNA editing, the interplay between dietary carbohydrates and proteins in regulating metabolism of liver cells, the effects of metal ions on protein synthesis, and much more. Nutrition and Gene Expression is an important reference for nutritionists, physiologists, biochemists, clinical nutritionists, pharmaceutical researchers, geneticists, and food scientists.


The Enlightened Gene

The Enlightened Gene

Author: Arri Eisen

Publisher: University Press of New England

Published: 2017-10-03

Total Pages: 274

ISBN-13: 151260125X

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Eight years ago, in an unprecedented intellectual endeavor, the Dalai Lama invited Emory University to integrate modern science into the education of the thousands of Tibetan Buddhist monks and nuns in exile in India. This project, the Emory Tibet Science Initiative, became the first major change in the monastic curriculum in six centuries. Eight years in, the results are transformative. The singular backdrop of teaching science to Tibetan Buddhist monks and nuns offered provocative insights into how science and religion can work together to enrich each other, as well as to shed light on life and what it means to be a thinking, biological human. In The Enlightened Gene, Emory University Professor Dr. Arri Eisen, together with monk Geshe Yungdrung Konchok explore the striking ways in which the integration of Buddhism with cutting-edge discoveries in the biological sciences can change our understanding of life and how we live it. What this book discovers along the way will fundamentally change the way you think. Are humans inherently good? Where does compassion come from? Is death essential for life? Is experience inherited? These questions have occupied philosophers, religious thinkers and scientists since the dawn of civilization, but in today's political discourse, much of the dialogue surrounding them and larger issues-such as climate change, abortion, genetically modified organisms, and evolution-are often framed as a dichotomy of science versus spirituality. Strikingly, many of new biological discoveries-such as the millions of microbes that we now know live together as part of each of us, the connections between those microbes and our immune systems, the nature of our genomes and how they respond to the environment, and how this response might be passed to future generations-can actually be read as moving science closer to spiritual concepts, rather than further away. The Enlightened Gene opens up and lays a foundation for serious conversations, integrating science and spirit in tackling life's big questions. Each chapter integrates Buddhism and biology and uses striking examples of how doing so changes our understanding of life and how we lead it.


Antioxidants and Functional Foods for Neurodegenerative Disorders

Antioxidants and Functional Foods for Neurodegenerative Disorders

Author: Abhai Kumar

Publisher: CRC Press

Published: 2021-01-07

Total Pages: 631

ISBN-13: 1000282740

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Neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are a growing problem across the world’s aging population. Oxidative stress in the brain plays a central role in a common pathophysiology of these diseases. This book presents scientific research on the potential of antioxidant therapy in the prevention and treatment of neurodegenerative disorders. This book outlines the roles of oxidative stress and diabetes mellitus in neurodegeneration, describes the molecular mechanisms of neurodegenerative disorders including the roles of environmental pollutants and inflammatory responses, and explores mitochondrial dysfunction. It then describes the protective abilities of antioxidants – including vitamin D, tocotrienol and coenzyme Q10 – against neurodegeneration. The book demonstrates the therapeutic potential of ketogenic diets, and highlights the roles of medicinal plants, phytopharmaceuticals, traditional medicines and food nutrients in neuroprotection. Key Features: Explains damage caused by numerous neurodegenerative disorders and the possible protection offered by antioxidants and functional foods. Describes molecular mechanisms of neurodegeneration by oxidative stress, advancing age, diabetes and mitochondrial dysfunctions. Demonstrates protection offered by nutraceuticals, antioxidants, botanical extracts and functional foods. The book contains twenty-three chapters divided into six sections written by leading researchers. This book is essential reading for health professionals, dietitians, food and nutrition scientists and anyone wanting to improve their knowledge of etiology of neurodegenerative diseases.


Opening Science

Opening Science

Author: Sönke Bartling

Publisher: Springer

Published: 2013-12-16

Total Pages: 325

ISBN-13: 3319000268

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Modern information and communication technologies, together with a cultural upheaval within the research community, have profoundly changed research in nearly every aspect. Ranging from sharing and discussing ideas in social networks for scientists to new collaborative environments and novel publication formats, knowledge creation and dissemination as we know it is experiencing a vigorous shift towards increased transparency, collaboration and accessibility. Many assume that research workflows will change more in the next 20 years than they have in the last 200. This book provides researchers, decision makers, and other scientific stakeholders with a snapshot of the basics, the tools, and the underlying visions that drive the current scientific (r)evolution, often called ‘Open Science.’


Gene Eating

Gene Eating

Author: Giles Yeo

Publisher: Simon and Schuster

Published: 2019-06-04

Total Pages: 352

ISBN-13: 1643131699

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In an age of misinformation and pseudo-science, the world is getting fatter and the diet makers are getting richer. So how do we break this cycle that’s literally killing us all?Drawing on the very latest science and his own genetic research at the University of Cambridge, Dr. Giles Yeo has written the seminal “anti-diet” diet book. Exploring the history of our food, debunking marketing nonsense, detoxifying diet advice, and confronting the advocates of clean eating, Giles translates his pioneering research into an engaging, must-read study of the human appetite.In a post-truth world, Gene Eating cuts straight to the data-driven facts. Only by understanding the physiology of our bodies, their hormonal functions, and their caloric needs can we overcome the mis- information of modern dieting trends, empower ourselves to make better decisions, and achieve healthy relationships with food, our bodies, and our weight.Inspiring and revelatory, filled with lively anecdotes and fascinating details, Gene Eating is an urgent and essential book that will change the way we eat.


The $1,000 Genome

The $1,000 Genome

Author: Kevin Davies

Publisher: Simon and Schuster

Published: 2015-08-18

Total Pages: 352

ISBN-13: 1416569618

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In 2000, President Bill Clinton signaled the completion of the Human Genome Project at a cost in excess of $2 billion. A decade later, the price for any of us to order our own personal genome sequence--a comprehensive map of the 3 billion letters in our DNA--is rapidly and inevitably dropping to just $1,000. Dozens of men and women--scientists, entrepreneurs, celebrities, and patients--have already been sequenced, pioneers in a bold new era of personalized genomic medicine. The $1,000 genome has long been considered the tipping point that would open the floodgates to this revolution. Do you have gene variants associated with Alzheimer's or diabetes, heart disease or cancer? Which drugs should you consider taking for various diseases, and at what dosage? In the years to come, doctors will likely be able to tackle all of these questions--and many more--by using a computer in their offices to call up your unique genome sequence, which will become as much a part of your medical record as your blood pressure.


Welcome to the Genome

Welcome to the Genome

Author: Robert DeSalle

Publisher: John Wiley & Sons

Published: 2020-01-29

Total Pages: 275

ISBN-13: 1118750306

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The popular introduction to the genomic revolution for non-scientists—the revised and updated new edition Welcome to the Genome is an accessible, up-to-date introduction to genomics—the interdisciplinary field of biology focused on the structure, function, evolution, mapping, and editing of an organism's complete set of DNA. Written for non-experts, this user-friendly book explains how genomes are sequenced and explores the discoveries and challenges of this revolutionary technology. Genomics is a mixture of many fields, including not only biology, engineering, computer science, and mathematics, but also social sciences and humanities. This unique guide addresses both the science of genomics and the ethical, moral, and social questions that rise from the technology. There have been many exciting developments in genomics since this book's first publication. Accordingly, the second edition of Welcome to the Genome offers substantial new and updated content to reflect recent major advances in genome-level sequencing and analysis, and demonstrates the vast increase in biological knowledge over the past decade. New sections cover next-generation technologies such as Illumina and PacBio sequencing, while expanded chapters discuss controversial ethical and philosophical issues raised by genomic technology, such as direct-to-consumer genetic testing. An essential resource for understanding the still-evolving genomic revolution, this book: Introduces non-scientists to basic molecular principles and illustrates how they are shaping the genomic revolution in medicine, biology, and conservation biology Explores a wide range of topics within the field such as genetic diversity, genome structure, genetic cloning, forensic genetics, and more Includes full-color illustrations and topical examples Presents material in an accessible, user-friendly style, requiring no expertise in genomics Discusses past discoveries, current research, and future possibilities in the field Sponsored by the American Museum of Natural History, Welcome to the Genome: A User's Guide to the Genetic Past, Present, and Future is a must-read book for anyone interested in the scientific foundation for understanding the development and evolutionary heritage of all life.


Genes and Aging

Genes and Aging

Author: M. S. Kanungo

Publisher: Cambridge University Press

Published: 1994-03-25

Total Pages: 336

ISBN-13: 9780521382991

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This book reviews the molecular biology of the gene in relation to aging. The author presents basic information on eukaryotic genes and follows this with details of the changes that occur in their structure and function during aging. He reviews the latest studies being carried out in various laboratories, outlines the gaps and deficiencies in our present knowledge, and suggests the most profitable future areas of research.


Instant Pathology

Instant Pathology

Author: Neil R. Borley

Publisher: Wiley-Blackwell

Published: 2007-05-29

Total Pages: 210

ISBN-13: 1405132906

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Indispensable dip-in revision aid Instant Pathology is the latest addition to the Instant series of basic science revision aids. It presents the fundamental pathological information needed for clinical practice in an easily accessible dip-in format. Each topic is concisely displayed in a double-page spread and is broken into two sections. The first covers general pathology and processes; the second is split into organ-specific pathology. Ideal for junior doctors and MRCP / MRCS candidates medical students on clinical attachments nurses and other allied health professionals