The Design of Experiments in Neuroscience
The Design of Experiments in Neuroscience

Author: Mary E. Harrington

Publisher: Cambridge University Press

Published: 2020-02-06

Total Pages: 201

ISBN-13: 1108656331

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Using engaging prose, Mary E. Harrington introduces neuroscience students to the principles of scientific research including selecting a topic, designing an experiment, analyzing data, and presenting research. This new third edition updates and clarifies the book's wealth of examples while maintaining the clear and effective practical advice of the previous editions. New and expanded topics in this edition include techniques such as optogenetics and conditional transgenes as well as a discussion of rigor and reproducibility in neuroscience research. Extended coverage of descriptive and inferential statistics arms readers with the analytical tools needed to interpret data. Throughout, practical guidelines are provided on avoiding experimental design problems, presenting research including creating posters and giving talks, and using a '12-step guide' to reading scientific journal articles.

The Design of Experiments in Neuroscience
The Design of Experiments in Neuroscience

Author: Mary Harrington

Publisher: SAGE

Published: 2011

Total Pages: 281

ISBN-13: 1412974321

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Originally published in 2006, the second edition of The Design of Experiments in Neuroscience continues to be an excellent and eminently readable guideline for students beginning their scientific careers. Although all of the examples are specific to neuroscience, this slender volume offers valuable illumination on core practices, principles, and experimental approaches pertinent for all new researchers. Chapter topics cover recognizing pseudoscience, ethics, how to critically read journal articles, how to pick an experimental question, basic research design, controlling variables, and tips for becoming an independent investigator. Each of the eight chapters provides descriptive figures and extra information boxes, questions to check reader comprehension, additional thought questions, further reading suggestions, and Web resources. The six appendixes are as valuable as the main text, including information on working with data, writing research papers, a sample paper, questions and exercises for review, a glossary, and answers to chapter questions. Neuroscientist Harrington (Smith College) has created a wonderful resource that should be a must read for every neuroscientist in training, if not all novice scientists. Summing Up: Highly recommended. Upper-division undergraduates and graduate students. Upper-division Undergraduates; Graduate Students. Reviewed by C. L. Iwema.

Guide to Research Techniques in Neuroscience
Guide to Research Techniques in Neuroscience

Author: Matt Carter

Publisher: Academic Press

Published: 2022-03-26

Total Pages: 416

ISBN-13: 0323915612

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Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step

Design of Experiments for Engineers and Scientists
Design of Experiments for Engineers and Scientists

Author: Jiju Antony

Publisher: Elsevier

Published: 2014-02-22

Total Pages: 221

ISBN-13: 0080994199

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The tools and techniques used in Design of Experiments (DoE) have been proven successful in meeting the challenge of continuous improvement in many manufacturing organisations over the last two decades. However research has shown that application of this powerful technique in many companies is limited due to a lack of statistical knowledge required for its effective implementation.Although many books have been written on this subject, they are mainly by statisticians, for statisticians and not appropriate for engineers. Design of Experiments for Engineers and Scientists overcomes the problem of statistics by taking a unique approach using graphical tools. The same outcomes and conclusions are reached as through using statistical methods and readers will find the concepts in this book both familiar and easy to understand.This new edition includes a chapter on the role of DoE within Six Sigma methodology and also shows through the use of simple case studies its importance in the service industry. It is essential reading for engineers and scientists from all disciplines tackling all kinds of manufacturing, product and process quality problems and will be an ideal resource for students of this topic. - Written in non-statistical language, the book is an essential and accessible text for scientists and engineers who want to learn how to use DoE - Explains why teaching DoE techniques in the improvement phase of Six Sigma is an important part of problem solving methodology - New edition includes a full chapter on DoE for services as well as case studies illustrating its wider application in the service industry

Designing EEG Experiments for Studying the Brain
Designing EEG Experiments for Studying the Brain

Author: Aamir Saeed Malik

Publisher: Academic Press

Published: 2017-05-25

Total Pages: 297

ISBN-13: 0128111410

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Designing EEG Experiments for Studying the Brain: Design Code and Example Datasets details the design of various brain experiments using electroencephalogram (EEG). Providing guidelines for designing an EEG experiment, it is primarily for researchers who want to venture into this field by designing their own experiments as well as those who are excited about neuroscience and want to explore various applications related to the brain. The first chapter describes how to design an EEG experiment and details the various parameters that should be considered for success, while remaining chapters provide experiment design for a number of neurological applications, both clinical and behavioral. As each chapter is accompanied with experiment design codes and example datasets, those interested can quickly design their own experiments or use the current design for their own purposes. Helpful appendices provide various forms for one's experiment including recruitment forms, feedback forms, ethics forms, and recommendations for related hardware equipment and software for data acquisition, processing, and analysis. - Written to assist neuroscientists in experiment designs using EEG - Presents a step-by-step approach to designing both clinical and behavioral EEG experiments - Includes experiment design codes and example datasets - Provides inclusion and exclusion criteria to help correctly identify experiment subjects and the minimum number of samples - Includes appendices that provide recruitment forms, ethics forms, and various subjective tests associated with each of the chapters

Experimental Design for Laboratory Biologists
Experimental Design for Laboratory Biologists

Author: Stanley E. Lazic

Publisher: Cambridge University Press

Published: 2016-12-08

Total Pages: 429

ISBN-13: 1316810674

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Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.

Building Experiments in PsychoPy
Building Experiments in PsychoPy

Author: Jonathan Peirce

Publisher: SAGE

Published: 2022-01-12

Total Pages: 313

ISBN-13: 1529788692

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PsychoPy is an open-source software package for creating rich, dynamic experiments in psychology, neuroscience and linguistics. Written by its creator, this book walks you through the steps of building experiments in PsychoPy, from using images to discovering lesser-known features, and from analysing data to debugging your experiment. Divided into three parts and with unique extension exercises to guide you at whatever level you are at, this textbook is the perfect tool for teaching practical undergraduate classes on research methods, as well as acting as a comprehensive reference text for the professional scientist. Essential reading for anyone using PsychoPy software, the second edition has been fully updated and includes multiple new chapters about features included in recent versions of PsychoPy, including running studies online and collecting survey data. Part I teaches you all the basic skills you need (and some more advanced tips along the way) to design experiments in behavioral sciences. Each chapter introduces anew concept but will offer a series of working experiments that you can build on. Part II presents more details important for professional scientists intending to use PsychoPy for published research. This part is recommended reading for science professionals in any discipline. Part III covers a range of specialist topics, such as those doing fMRI research, or those studying visual perception. "This book fills an incredibly important gap in the field. Many users of PsychoPy will be excited to learn that there is now a highly accessible and well-designed written guide to refine their skills." – Susanne Quadflieg, University of Bristol

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research
Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Author: National Research Council

Publisher: National Academies Press

Published: 2003-08-22

Total Pages: 223

ISBN-13: 030916785X

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Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

The Neuroscience of You
The Neuroscience of You

Author: Chantel Prat

Publisher: Penguin

Published: 2022-08-02

Total Pages: 385

ISBN-13: 1524746614

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From University of Washington professor Chantel Prat comes The Neuroscience of You, a rollicking adventure into the human brain that reveals the surprising truth about neuroscience, shifting our focus from what’s average to an understanding of how every brain is different, exactly why our quirks are important, and what this means for each of us. With style and wit, Chantel Prat takes us on a tour of the meaningful ways that our brains are dissimilar from one another. Using real-world examples, along with take-them-yourself tests and quizzes, she shows you how to identify the strengths and weakness of your own brain, while learning what might be going on in the brains of those who are unlike you. With sections like “Focus,” “Navigate,” and “Connect,” The Neuroscience of You helps us see how brains that are engineered differently ultimately take diverse paths when it comes time to prioritize information, use what they’ve learned from experience, relate to other people, and so much more. While other scientists focus on how “the” brain works “on average,” Prat argues that our obsession with commonalities has slowed our progress toward understanding the very things that make each of us unique and interesting. Her field-leading research, employing cutting-edge technology, reveals the truth: Complicated as it may be, no two brains are alike. And individual differences in brain functioning are as pervasive as they are fundamental to defining what “normal” looks like. Adages such as, “I’m not wired that way” intuitively point to the fact that the brains we’re piloting, educating, and parenting are wonderfully distinct, explaining a whole host of phenomena, from how easily a person might learn a second language in adulthood to whether someone feels curious or threatened when faced with new information. This book invites the reader to understand themselves and others by zooming in so close that we all look gray and squishy.