A Binding of Blood
A Binding of Blood

Author: Azalea Ellis

Publisher: Seladore Publishing

Published: 2021-12-26

Total Pages: 716

ISBN-13:

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To study magic at the University, Siobhan sacrificed her name. She sacrificed her body, and her past. Magically disguised as a boy named Sebastien, she is learning wondrous secrets of the thaumaturgic sciences. As Sebastien, she mingles with the young nobles who will one day rule their country. But danger is closer than ever, and she cannot escape her past. The coppers investigating the theft of Siobhan's priceless transformation artifact have given her a new name. The Raven Queen. As Siobhan does favors for the gang that loaned her the University tuition, the Raven Queen's mystique only grows. And keeps growing... ...Snowballing out of control until Siobhan's other identity takes on a life of its own, a fear-inducing bogeyman well beyond the truth of her real capabilities. With the whole city out to get her and trouble hounding both sides of her double life, how will Siobhan ever survive to become the world's most powerful sorcerer?

Regulation of Tissue Oxygenation, Second Edition
Regulation of Tissue Oxygenation, Second Edition

Author: Roland N. Pittman

Publisher: Biota Publishing

Published: 2016-08-18

Total Pages: 117

ISBN-13: 1615047212

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This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Of Blood and Fire
Of Blood and Fire

Author: Ryan Cahill

Publisher:

Published: 2021-02-22

Total Pages: 542

ISBN-13: 9781838381806

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Of Blood and Fire is a classic Epic Fantasy adventure. It takes all the familiar fantasy tropes - elves, dwarves, giants, and dragons - and adds a fresh, contemporary twist.

The Book of Blood and Shadow
The Book of Blood and Shadow

Author: Robin Wasserman

Publisher: Ember

Published: 2012

Total Pages: 466

ISBN-13: 0375872779

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While working on a project translating letters from sixteenth-century Prague, high school senior Nora Kane discovers her best friend murdered with her boyfriend the apparent killer and is caught up in a dangerous web of secret societies and shadowy conspirators, all searching for a mysterious ancient device purported to allow direct communication with God.

The Binding
The Binding

Author: Bridget Collins

Publisher: HarperCollins

Published: 2019-04-09

Total Pages: 473

ISBN-13: 0062838113

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NATIONAL BESTSELLER A NEW YORK TIMES BOOK REVIEW EDITORS' CHOICE Proclaimed as “truly spellbinding,” a “great fable” that “functions as transporting romance” by the Guardian, the runaway #1 international bestseller "A rich, gothic entertainment that explores what books have trapped inside them and reminds us of the power of storytelling. Spellbinding.” — TRACY CHEVALIER Imagine you could erase grief. Imagine you could remove pain. Imagine you could hide the darkest, most horrifying secret. Forever. Young Emmett Farmer is working in the fields when a strange letter arrives summoning him away from his family. He is to begin an apprenticeship as a Bookbinder—a vocation that arouses fear, superstition, and prejudice amongst their small community, but one neither he nor his parents can afford to refuse. For as long as he can recall, Emmett has been drawn to books, even though they are strictly forbidden. Bookbinding is a sacred calling, Seredith informs her new apprentice, and he is a binder born. Under the old woman’s watchful eye, Emmett learns to hand-craft the elegant leather-bound volumes. Within each one they will capture something unique and extraordinary: a memory. If there’s something you want to forget, a binder can help. If there’s something you need to erase, they can assist. Within the pages of the books they create, secrets are concealed and the past is locked away. In a vault under his mentor’s workshop rows upon rows of books are meticulously stored. But while Seredith is an artisan, there are others of their kind, avaricious and amoral tradesman who use their talents for dark ends—and just as Emmett begins to settle into his new circumstances, he makes an astonishing discovery: one of the books has his name on it. Soon, everything he thought he understood about his life will be dramatically rewritten. An unforgettable novel of enchantment, mystery, memory, and forbidden love, The Binding is a beautiful homage to the allure and life-changing power of books—and a reminder to us all that knowledge can be its own kind of magic.

A Conjuring of Ravens
A Conjuring of Ravens

Author: Azalea Ellis

Publisher: Seladore Publishing

Published: 2021-02-11

Total Pages: 512

ISBN-13:

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In a world where magic is a science, Siobhan is a genius. But even geniuses need schooling. Siobhan has just been banned from the country's only magical university. As the unwitting accomplice to the theft of a priceless magical artifact, she has suddenly become a wanted criminal. There are fates worse than death, and if caught, she will face them. Unwilling to give up on her dream of becoming the world's most powerful sorcerer, she resolves to do whatever it takes to change her fate. Even if it means magically disguising herself as a man and indebting herself to a gang of criminals to pay for University tuition. With the coppers after her, the pressure of trying to keep her spot in the devilishly competitive magic classes, and the gang calling in favors to repay her debts, Siobhan will need every drop of magic she can channel. Search terms: magepunk, progression fantasy, hard fantasy, unique magic system, realistic magic system, magic university, academy fantasy, magic lessons, gender bender, gender switch, gaslamp, spellcasting, sorcerers, witches, scp, alternate universe fantasy, alternate world fantasy, historical fantasy, magical creatures

Heir of Fire
Heir of Fire

Author: Sarah J. Maas

Publisher: Bloomsbury Publishing USA

Published: 2014-09-02

Total Pages: 596

ISBN-13: 1619630664

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The heir of ash and fire bows to no one. A new threat rises in the third book in the #1 bestselling Throne of Glass series by Sarah J. Maas. Celaena Sardothien has survived deadly contests and shattering heartbreak, but now she must travel to a new land to confront her darkest truth. That truth could change her life-and her future-forever. Meanwhile, monstrous forces are gathering on the horizon, intent on enslaving her world. To defeat them, Celaena will need the strength not only to fight the evil that is about to be unleashed but also to harness her inner demons. If she is to win this battle, she must find the courage to face her destiny-and burn brighter than ever before. The third book in the #1 New York Times bestselling Throne of Glass series continues Celaena's epic journey from woman to warrior.

Of Darkness and Light
Of Darkness and Light

Author: Ryan Cahill

Publisher:

Published: 2021-12-31

Total Pages: 710

ISBN-13: 9781838381868

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The hotly anticipated second book in Ryan Cahill's break out debut series, The Bound and The Broken. Heroes will rise. Nations will fall. Behind the towering walls of Belduar, Calen Bryer and his companions stand in defense of the city and its new king. In over a thousand years, Belduar has never fallen. It has stood as a bastion of hope. But the Lorian empire are at its walls once more, and the Dragonguard are coming. In the North, with Faenir by her side, Calen's sister Ella arrives at the port of Antiquar. She holds no fear of the unknown. She will see this through, no matter what - or who - gets in her way. Meanwhile, at the embassy of the Circle of Magii in Al'Nasla, Rist Havel hones his newfound powers in preparation for the trials. Unbeknownst to Rist, he is being watched, measured, and judged. He was not taken into the Circle by chance. There is greatness in him. But great men can do terrible things. As Lorian forces land on southern shores and Aeson Virandr's letters of rebellion find their way to the right hands, only the Knights of Achyron see the true danger. The danger that stirs in the darkness. The coming shadow will not stop. It will consume all in its path. It wants for nothing but blood and fire.

Preclinical Development Handbook
Preclinical Development Handbook

Author: Shayne Cox Gad

Publisher: John Wiley & Sons

Published: 2008-03-21

Total Pages: 1352

ISBN-13: 0470249021

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A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for current methods and techniques. Each chapter is written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor has carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear. Among the key topics covered are: * Modeling and informatics in drug design * Bioanalytical chemistry * Absorption of drugs after oral administration * Transporter interactions in the ADME pathway of drugs * Metabolism kinetics * Mechanisms and consequences of drug-drug interactions Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage. This publication should be readily accessible to all pharmaceutical scientists involved in preclinical testing, enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.