Biosynthesis of Aromatic Compounds
Biosynthesis of Aromatic Compounds

Author: G. Billek

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 153

ISBN-13: 1483164373

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Biosynthesis of Aromatic Compounds is a collection of papers from the Proceedings of the Second Meeting of the Federation of European Biochemical Societies in Vienna, on April 21-24, 1965. This volume is based on lectures given at the symposium and covers the studies made on the biosynthesis of aromatic compounds. The first part discusses the biosynthetic intermediates in polyketide biosynthesis in connection with the biosynthesis of fatty acids; it also notes the biosynthesis of coumarins that form from derivatives of carbohydrate metabolism. Other results concerning the biosynthesis of benzoic acids and on compounds such as substituted benzaldehydes and benzylalcohols are presented. Another paper shows that when species of mycobacteria are grown under iron-deficient conditions, salicylic acid can be produced. The second part focuses on studies made on the biosynthesis of aromatic compounds that contain hetero atoms. The formation of aromatic systems in alkaloids and the biosynthesis of some alkaloids based on aromatic precursors are analyzed. The book explains that some flavor compounds such as mustard oils are the product of enzymatic hydrolysis of thioglucosides, and then notes that the biogenetic schemes of Mentzer et al. concerning another study are not suitable as working hypotheses. This collection can be read profitably by chemists, biochemists, and academicians involved in aromatic compound researches.

Systems Metabolic Engineering
Systems Metabolic Engineering

Author: Christoph Wittmann

Publisher: Springer Science & Business Media

Published: 2012-06-15

Total Pages: 391

ISBN-13: 9400745346

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Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.

The Shikimate Pathway
The Shikimate Pathway

Author: Edwin Haslam

Publisher: Elsevier

Published: 2014-05-20

Total Pages: 327

ISBN-13: 1483161188

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The Shikimate Pathway gives a bird's eye view of the shikimate pathway and its implications for the life of a range of organisms. Topics covered in this book include the chemistry of intermediates in the shikimate pathway; biosynthesis of aromatic amino acids in this pathway; its metabolites; and its role in higher plants. This book is comprised of six chapters and begins by introducing the reader to shikimic acid, a natural product derived from the plant Illicium religiosum, along with the mechanistic and stereochemical aspects of the reactions of the shikimate pathway. The biosynthesis of aromatic amino acids from chorismate is also described, and then the discussion turns to the chemical properties and the detailed stereochemistry of intermediates and enzymes in the shikimate pathway. The next chapter examines the biosynthesis of isoprenoid quinones involved in electron transport and the folic acid group of co-enzymes in the shikimate pathway. The metabolism of the aromatic amino acids in microorganisms and higher organisms is considered, along with the biosynthesis and physiological functions of phenylpropanoid compounds and their derivatives in the shikimate pathway in higher plants. This book will be of general value to practitioners in the many and varied areas of biochemical research associated with metabolism.

Plant Hormones
Plant Hormones

Author: Peter J. Davies

Publisher: Springer Science & Business Media

Published: 2007-11-06

Total Pages: 830

ISBN-13: 1402026862

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Plant hormones play a crucial role in controlling the way in which plants grow and develop. While metabolism provides the power and building blocks for plant life, it is the hormones that regulate the speed of growth of the individual parts and integrate them to produce the form that we recognize as a plant. This book is a description of these natural chemicals: how they are synthesized and metabolized, how they act at both the organismal and molecular levels, how we measure them, a description of some of the roles they play in regulating plant growth and development, and the prospects for the genetic engineering of hormone levels or responses in crop plants. This is an updated revision of the third edition of the highly acclaimed text. Thirty-three chapters, including two totally new chapters plus four chapter updates, written by a group of fifty-five international experts, provide the latest information on Plant Hormones, particularly with reference to such new topics as signal transduction, brassinosteroids, responses to disease, and expansins. The book is not a conference proceedings but a selected collection of carefully integrated and illustrated reviews describing our knowledge of plant hormones and the experimental work that is the foundation of this information. The Revised 3rd Edition adds important information that has emerged since the original publication of the 3rd edition. This includes information on the receptors for auxin, gibberellin, abscisic acid and jasmonates, in addition to new chapters on strigolactones, the branching hormones, and florigen, the flowering hormone.

Chemistry of Plant Natural Products
Chemistry of Plant Natural Products

Author: Sunil Kumar Talapatra

Publisher: Springer

Published: 2015-03-05

Total Pages: 1197

ISBN-13: 3642454100

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Aimed at advanced undergraduate and graduate students and researchers working with natural products, Professors Sunil and Bani Talapatra provide a highly accessible compilation describing all aspects of plant natural products. Beginning with a general introduction to set the context, the authors then go on to carefully detail nomenclature, occurrence, isolation, detection, structure elucidation (by both degradation and spectroscopic techniques) stereochemistry, conformation, synthesis, biosynthesis, biological activity and commercial applications of the most important natural products of plant origin. Each chapter also includes detailed references (with titles) and a list of recommended books for additional study making this outstanding treatise a useful resource for teachers of chemistry and researchers working in universities, research institutes and industry.

Chemical and Biological Synthesis
Chemical and Biological Synthesis

Author: Nick J Westwood

Publisher: Royal Society of Chemistry

Published: 2018-08-16

Total Pages: 317

ISBN-13: 178801507X

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Synthetic chemistry plays a central role in many areas of chemical biology; utilising recent case studies, the goal of Chemical and Biological Synthesis is to highlight the full impact that the preparation of novel reagents can have in chemical biology. Covering the synthetic approaches that can be applied across the whole field of chemical biology, this book provides synthetic chemists with the broader context to which their work contributes and the biological questions that can be addressed through it. An ideal guide for postgraduate students and researchers in synthetic organic chemistry and chemical biology, Chemical and Biological Synthesis introduces synthetic techniques and methods to those who wish to incorporate synthesis for the first time in their biology-focused research programmes.

Aromatic C-nitroso Compounds
Aromatic C-nitroso Compounds

Author: Hrvoj Vančik

Publisher: Springer Science & Business Media

Published: 2013-03-12

Total Pages: 168

ISBN-13: 9400763379

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This book is designed to collect and review the research covering main directions in investigations of aromatic nitroso compounds in last decades, and to present both, the academic aspects of this chemistry, as well as the open field of its applicability. The book is divided in five chapters. The basic structural properties of the nitroso aromatic molecules are described in the first chapter. The second chapter is an overview of the methods of preparations of aromatic nitroso and polynitroso compounds, including classical synthetic methods and some new preparative approaches. The third part deals with the physico-chemical properties of nitroso aromates and azodioxides, its structure, crystallography, quantum chemical calculations, spectroscopy, typical reactions, and especially it is focused on the dimerizations in the solid-state. In the fourth chapter is represented organometallic chemistry of nitroso aromatic molecules and its applications in catalysis. The last part of the book deals with the behavior of this class of compounds in the biological systems, reactions with biomolecules and the use in toxicology.

Biosynthesis
Biosynthesis

Author: Finian J. Leeper

Publisher: Springer

Published: 2003-07-01

Total Pages: 255

ISBN-13: 354048146X

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This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The first volume covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them opens the door to combinatorial biosynthesis as well as to the production of targeted pharmaceutical agents utilizing a combination of chemistry, molecular biology and protein biochemistry.

Plant Polyphenols
Plant Polyphenols

Author: Richard W. Hemingway

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 1027

ISBN-13: 1461534763

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This book was developed from the proceedings of the 2nd North American Tan nin Conference held in Houghton, Michigan, June, 1991. The objective of this con ference was to bring together people with a common interest in plant polyphenols and to promote interdisciplinary interactions that will lead to a bet ter understand ing of the importance of these substances. Another objective of this conference was to extend the 'tannin family' by making special efforts to encourage participation by scientists outside the United States, obtain more coverage of the hydrolyzable tannins, and further broaden the scope of coverage from the initial concentration on forestry and forest products. Com parison of the contents of this book with 'Chemistry and Significance of Condensed Tannins' that resulted from the proceedings of the 1st North American Tannin Conference shows the degree that these objectives were met. In developing the second conference, care was taken to assure that this book extends rather than duplicates the coverage of the first conference. Therefore, the two books should be taken together to obtain an up to date coverage of the broad area of chemistry and significance of plant polyphenols. Our thanks go to the authors who so kindly contributed chapters and so pa tiently responded to our requests. We thank the Conference Assistance Staff of Michigan Technological University for their help in planning and conducting the conference.