Disenchanted Night
Disenchanted Night

Author: Wolfgang Schivelbusch

Publisher: Univ of California Press

Published: 1995-12-20

Total Pages: 270

ISBN-13: 9780520203549

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Wolfgang Schivelbusch tells the story of the development of artificial light in the nineteenth century. Not simply a history of a technology, Disenchanted Night reveals the ways that the technology of artificial illumination helped forge modern consciousness. In his strikingly illustrated and lively narrative, Schivelbusch discusses a range of subjects including the political symbolism of streetlamps, the rise of nightlife and the shopwindow, and the importance of the salon in bourgeois culture.

Theory and Practice of Direct Methods in Crystallography
Theory and Practice of Direct Methods in Crystallography

Author: M. F. C. Ladd

Publisher: Springer

Published: 1980-01-31

Total Pages: 450

ISBN-13:

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Direct methods of crystal structure determination are usually associated with techniques in which phases for a set of structure factors are determined from the corresponding experimental amplitudes by probabilistic calcula tions. It is thus implied that such ab initio phase calculations do not require a knowledge of atomic positions, and this basis distinguishes direct methods from other techniques for structure determination. An acceptably wider interpretation of the term direct methods leads to other important applica tions involving, inter alia, the use of heavy atoms, resolution-limited phase data for large molecules, rotation functions, and Fourier series. These topics are discussed in the later chapters of this book. Although some earlier theoretical investigations were made by Harker and Kaspar, direct methods may be considered to have begun around the year 1950. Important landmarks in the development of the subject include the book by Hauptmann and Karle, The Centrosymmetric Crystal (1953), the definitive paper by Karle and Karle in Acta Crystallographica (1966), and the recent (1978) sophisticated program package MULTAN 78 produced mainly by Germain, Main, and Woolfson. Woolfson's book, Direct Methods in Crystallography, was published in 1961, but because of the rapid progress in direct methods, much of it soon became outmoded. It is interesting to note that direct methods nearly came into being many years earlier. Certainly the E2 relationship was used implicitly by Lonsdale in 1928 in determining the crystal structure of hexamethylbenzene.

SARS-CoV-2 Spike Protein Convergent Evolution
SARS-CoV-2 Spike Protein Convergent Evolution

Author: Daniele Focosi

Publisher: Springer Nature

Published: 2021-10-11

Total Pages: 140

ISBN-13: 3030873242

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This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.

Dynamic Capabilities and Relationships
Dynamic Capabilities and Relationships

Author: Tomás Bayón

Publisher: Springer Nature

Published: 2021-10-27

Total Pages: 150

ISBN-13: 3030831825

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Building on the seminal work of David Teece, Kathleen Eisenhardt, Jeffrey Martin, and others, this volume applies the concept of dynamic capabilities to help readers understand how organizations can be successful in highly dynamic environments. The contributions, written by researchers who participated in the research program "Dynamic Capabilities and Relationships" and international researchers who participated in the program’s international conference (both funded by the Dieter Schwarz Foundation), highlight state-of-the-art research on dynamic capabilities and relationships. They also put forward an integrated management approach for the purpose of understanding, analyzing, and managing the successful creation and adaptation of capabilities and relationships.

Principles of Virology, Volume 2
Principles of Virology, Volume 2

Author: S. Jane Flint

Publisher: John Wiley & Sons

Published: 2020-11-03

Total Pages: 518

ISBN-13: 1683672852

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Principles of Virology, the leading virology textbook in use, is an extremely valuable and highly informative presentation of virology at the interface of modern cell biology and immunology. This text utilizes a uniquely rational approach by highlighting common principles and processes across all viruses. Using a set of representative viruses to illustrate the breadth of viral complexity, students are able to under-stand viral reproduction and pathogenesis and are equipped with the necessary tools for future encounters with new or understudied viruses. This fifth edition was updated to keep pace with the ever-changing field of virology. In addition to the beloved full-color illustrations, video interviews with leading scientists, movies, and links to exciting blogposts on relevant topics, this edition includes study questions and active learning puzzles in each chapter, as well as short descriptions regarding the key messages of references of special interest. Volume I: Molecular Biology focuses on the molecular processes of viral reproduction, from entry through release. Volume II: Pathogenesis and Control addresses the interplay between viruses and their host organisms, on both the micro- and macroscale, including chapters on public health, the immune response, vaccines and other antiviral strategies, viral evolution, and a brand new chapter on the therapeutic uses of viruses. These two volumes can be used for separate courses or together in a single course. Each includes a unique appendix, glossary, and links to internet resources. Principles of Virology, Fifth Edition, is ideal for teaching the strategies by which all viruses reproduce, spread within a host, and are maintained within populations. This edition carefully reflects the results of extensive vetting and feedback received from course instructors and students, making this renowned textbook even more appropriate for undergraduate and graduate courses in virology, microbiology, and infectious diseases.

Inside the State
Inside the State

Author: Kitty Calavita

Publisher: Quid Pro Books

Published: 2010-07-12

Total Pages: 443

ISBN-13: 1610270010

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A socio-political study of the rise and fall of the Bracero worker program and what it means for immigration policy and organizational theory. A classic book with continuing substantive and methodological value. As a new Foreword notes, worries about immigration and labor persist, as does basic dysfunction of the present form of INS. Digging deeper reveals the persistence of a structural catch-22.The digital edition features quality formatting, scaled tables, linked notes, active TOC, and even a fully linked subject-matter index.

Structural Biology in Immunology
Structural Biology in Immunology

Author: Chaim Putterman

Publisher: Academic Press

Published: 2018-05-14

Total Pages: 192

ISBN-13: 0128033703

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Structural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically altered. Furthermore, there is an increasing awareness of the critical role of the immune system in cancer biology. The improved central structure function relationships presented in this book will further enhance our ability to understand what defects in normal individuals can lead to disease. - Describes novel/recently discovered immunomodulatory proteins, including antibodies and co-stimulatory or co-inhibitory molecules - Emphasizes new biologic and small molecule drug design through the exploration of structure-function relationship - Features a collaborative editorial effort, involving clinical immunologists and structural biologists - Provides useful and practical insights on developing the necessary links between basic science and clinical therapy in immunology - Gives interested parties a bridge to learn about computer modeling and structure based design principles