Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications

Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications

Author: Neeraj Mishra

Publisher: Springer Nature

Published: 2023-11-29

Total Pages: 440

ISBN-13: 9819969174

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This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.


Polymer Micelles

Polymer Micelles

Author: Shin-ichi Yusa

Publisher: MDPI

Published: 2018-04-20

Total Pages: 229

ISBN-13: 3038428078

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This book is a printed edition of the Special Issue "Polymer Micelles" that was published in Polymers


Polymer-Engineered Nanostructures for Advanced Energy Applications

Polymer-Engineered Nanostructures for Advanced Energy Applications

Author: Zhiqun Lin

Publisher: Springer

Published: 2017-06-16

Total Pages: 717

ISBN-13: 331957003X

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This book provides a comprehensive overview of engineering nanostructures mediated by functional polymers in combination with optimal synthesis and processing techniques. The focus is on polymer-engineered nanostructures for advanced energy applications. It discusses a variety of polymers that function as precursors, templates, nano-reactors, surfactants, stabilizers, modifiers, dopants, and spacers for directing self-assembly, assisting organization, and templating growth of numerous diverse nanostructures. It also presents a wide range of polymer processing techniques that enable the efficient design and optimal fabrication of nanostructured polymers, inorganics, and organic–inorganic nanocomposites using in-situ hybridization and/or ex-situ recombination methodologies. Combining state-of-the-art knowledge from polymer-guided fabrication of advanced nanostructures and their unique properties, it especially highlights the new, cutting-edge breakthroughs, future horizons, and insights into such nanostructured materials in applications such as photovoltaics, fuel cells, thermoelectrics, piezoelectrics, ferroelectrics, batteries, supercapacitors, photocatalysis, and hydrogen generation and storage. It offers an instructive and approachable guide to polymer-engineered nanostructures for further development of advanced energy materials to meet ever-increasing global energy demands. Interdisciplinary and broad perspectives from internationally respected contributors ensure this book serves as a valuable reference source for scientists, students, and engineers working in polymer science, renewable energy materials, materials engineering, chemistry, physics, surface/interface science, and nanotechnology. It is also suitable as a textbook for universities, institutes, and industrial institutions.


Light-Sensitive Polymeric Nanoparticles Based on Photo-Cleavable Chromophores

Light-Sensitive Polymeric Nanoparticles Based on Photo-Cleavable Chromophores

Author: Daniel Klinger

Publisher: Springer Science & Business Media

Published: 2013-08-13

Total Pages: 236

ISBN-13: 3319004468

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The triggered release of functional compounds from such polymeric carriers as micelles, nanoparticles or nanogels is a rapidly developing and highly versatile concept which is expected to be one of the key approaches to future therapeutics. In his thesis, Daniel Klinger highlights the approach of stimuli-responsive microgels for such applications and discusses why especially light as a trigger has an outstanding position amongst the family of conventional stimuli. Based on these considerations, the author focuses on the design, synthesis and characterization of novel photo-sensitive microgels and nanoparticles as potential materials for the loading and light-triggered release/accessibility of functional compounds. Starting from the synthesis of photo-cleavable organic building blocks and their use in the preparation of polymeric nanoparticles, continuing to the examination of their loading and release profiles, and concluding with biological in vitro studies of the final materials, Daniel Klinger’s work is an excellent example of the multidisciplinary research needed for the successful development of new materials in this field and has led to a number of further publications in internationally respected journals.


Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications

Author: Abdel Salam Hamdy Makhlouf

Publisher: Woodhead Publishing

Published: 2018-06-14

Total Pages: 694

ISBN-13: 008101998X

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Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications, Volume One: Types and Triggers discusses, in detail, the recent trends in designing biodegradable and biocompatible single-responsive polymers and nanoparticles for safe drug delivery. Focusing on the most advanced materials and technologies, evaluation methods, and advanced synthesis techniques stimuli-responsive polymers, the book is an essential reference for scientists with an interest in drug delivery vehicles. Sections focus on innovation, development and the increased global demand for biodegradable and biocompatible responsive polymers and nanoparticles for safe drug delivery. - Offers an in-depth look at the basic and fundamental aspects of alternative stimuli-responsive polymers, mechanisms, structure, synthesis and properties - Provides a well-defined categorization for stimuli-responsive polymers for drug delivery based on different triggering mechanisms - Discusses novel approaches and challenges for scaling up and commercialization of stimuli-responsive polymers


Multi-Component and Sequential Reactions in Polymer Synthesis

Multi-Component and Sequential Reactions in Polymer Synthesis

Author: Patrick Theato

Publisher: Springer

Published: 2015-07-06

Total Pages: 209

ISBN-13: 3319207202

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The series Advances in Polymer Science presents critical reviews of the present and future trends in polymer and biopolymer science. It covers all areas of research in polymer and biopolymer science including chemistry, physical chemistry, physics, material science. The thematic volumes are addressed to scientists, whether at universities or in industry, who wish to keep abreast of the important advances in the covered topics. Advances in Polymer Science enjoys a longstanding tradition and good reputation in its community. Each volume is dedicated to a current topic and each review critically surveys one aspect of that topic, to place it within the context of the volume. The volumes typically summarize the significant developments of the last 5 to 10 years and discuss them critically, presenting selected examples, explaining and illustrating the important principles and bringing together many important references of primary literature. On that basis, future research directions in the area can be discussed. Advances in Polymer Science volumes thus are important references for every polymer scientist, as well as for other scientists interested in polymer science as an introduction to a neighboring field or as a compilation of detailed information for the specialist. Review articles for the individual volumes are invited by the volume editors. Single contributions can be specially commissioned. Readership: Polymer scientists or scientists in related fields interested in polymer and biopolymer science, at universities or in industry, graduate students.


Intracellular Delivery II

Intracellular Delivery II

Author: Aleš Prokop

Publisher: Springer

Published: 2014-05-20

Total Pages: 479

ISBN-13: 9401788960

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This volume is a continuation of Volume 1 following the previously published Editorial. More emphasis is given to novel nanocarrier designs, their characterization and function, and applications for drug discovery and treatment. A number of chapters will deal with nanofibers as a new major application within the biomedical field with a very high success rate particularly in wound healing and diabetic foot and spine injuries. A major new subdivision will deal with mathematical methods for the assembly of nanocarriers both for simulation and function.


Smart Polymers and their Applications

Smart Polymers and their Applications

Author: Maria Rosa Aguilar

Publisher: Elsevier

Published: 2014-02-19

Total Pages: 587

ISBN-13: 0857097024

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Smart polymers are polymers that respond to different stimuli or changes in the environment. Smart Polymers and their Applications reviews the types, synthesis, properties, and applications of smart polymers. Chapters in part one focus on types of polymers, including temperature-, pH-, photo-, and enzyme-responsive polymers. Shape memory polymers, smart polymer hydrogels, and self-healing polymer systems are also explored. Part two highlights applications of smart polymers, including smart instructive polymer substrates for tissue engineering; smart polymer nanocarriers for drug delivery; the use of smart polymers in medical devices for minimally invasive surgery, diagnosis, and other applications; and smart polymers for bioseparation and other biotechnology applications. Further chapters discuss the use of smart polymers for textile and packaging applications, and for optical data storage. Smart Polymers and their Applications is a technical resource for chemists, chemical engineers, mechanical engineers, and other professionals in the polymer industry; manufacturers in such sectors as medical, automotive, and aerospace engineering; and academic researchers in polymer science. - Reviews the different types of smart polymer, discussing their properties, structure, design, and characterization - Reviews applications of smart polymers in such areas as biomedical engineering, textiles, and food packaging


Multiphase Polymer Systems

Multiphase Polymer Systems

Author: Andreea Irina Barzic

Publisher: CRC Press

Published: 2016-09-19

Total Pages: 278

ISBN-13: 131535098X

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Phase morphology in multicomponent polymer-based systems represents the main physical characteristic that allows for control of the material design and implicitly the development of new plastics. Emphasizing properties of these promising new materials in both solution and solid phase, this book describes the preparation, processing, properties, and practical implications of advanced multiphase systems from macro to nanoscales. It covers a wide range of systems including copolymers, polymer blends, polymer composites, gels, interpenetrating polymers, and layered polymer/metal structures, describing aspects of polymer science, engineering, and technology. The book analyzes experimental and theoretical aspects regarding the thermal and electrical transport phenomena and magnetic properties of crucial importance in advanced technologies. It reviews the most recent advances concerning morphological, rheological, interfacial, physical, fire-resistant, thermophysical, and biomedical properties of multiphase polymer systems. Concomitantly the book deals with basic investigation techniques that are sensitive in elucidating the features of each phase. It also discusses the latest research trends that offer new solutions for advanced bio- and nanotechnologies. Introduces an overview of recent studies in the area of multiphase polymer systems, their micro- and nanostructural evolutions in advanced technologies, and provides future outlooks, new challenges and opportunities. Discusses multicomponent structures that offer enhanced physical, mechanical, thermal, electrical, magnetic, and optical properties adapted to current requirements of modern technologies. Covers a wide range of materials, such as composites, blends, alloys, gels and interpenetrating polymer networks. Presents new strategies for controlling the micro- and nanomorphology and the mechanical properties of multiphase polymeric materials. Describes different applications of multiphase polymeric materials in various fields, including automotive, aeronautics and space industry, displays, and medicine.


Handbook of Metathesis, 3 Volume Set

Handbook of Metathesis, 3 Volume Set

Author: Robert H. Grubbs

Publisher: John Wiley & Sons

Published: 2015-05-26

Total Pages: 1639

ISBN-13: 3527334246

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Covering the complete breadth of the olefin metathesis reaction. The second edition of the ultimate reference in this field is completely updated and features more than 80% new content, with the focus on new developments in the field, especially in industrial applications. No other book covers the topic in such a comprehensive manner and in such high quality, and this new edition retains the three-volume format: Catalyst Development, Applications in Organic Synthesis and Polymer Synthesis. Edited by a Nobel laureate in the field, and with a list of contributors that reads like a "Who's-Who" of metathesis, this is an indispensable one-stop reference for organic, polymer and industrial chemists, as well as chemists working with organometallics. Individual volumes also available separately to purchase Volume 1: Catalyst Development - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339485.html Volume 2: Applications in Organic Synthesis - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339493.html Volume 3: Polymer Synthesis - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339507.html