Coordination Chemistry of Macrocyclic Compounds
Coordination Chemistry of Macrocyclic Compounds

Author: Gordon Melson

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 676

ISBN-13: 1461329280

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Chemists have been aware of the existence of coordination compounds con taining organic macrocyclic ligands since the first part of this century ; however, only during the past few years have they expanded research into the chemistry of these compounds. The expansion was initiated in the early 1960s by the synthesis and characterization of compounds containing some new macrocyclic ligands. The synthesis of compounds which may serve as model systems for some natural products containing large rings as ligands provided the main goal for the early expansion of research effort; indeed, a recurrent theme behind much of the reported chemistry has been the analogy between synthetic macrocyclic compounds and many natural-product systems. More recently, the emphases of reported research have ranged over the whole spectrum of chemistry, and the number of publications that discuss macrocyclic chemistry has increased at a dramatic rate. The completed research has been reported in a variety of journals throughout the world but there has been no previous attempt to bring the major developments together under one cover. This book, therefore, attempts to satisfy the need for a single source in which there is both a collection and a correlation of information concerning the coordination chemistry of macrocyclic compounds. The chapters in this book discuss various aspects of macrocyclic chemistry, and while these chapters as a whole constitute an in-depth survey of the state-of the-art of the field, each chapter is written as a complete unit.

Synthesis,Biological Studies of Macrocyclic Transition Metal Complexes
Synthesis,Biological Studies of Macrocyclic Transition Metal Complexes

Author: Rayees Sheikh

Publisher: LAP Lambert Academic Publishing

Published: 2012-07

Total Pages: 156

ISBN-13: 9783659146572

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This book presents the important facts about the synthesis and biological studies of macrocyclic transition metal complexes. A detailed synthetic discussion of the reaction steps in each mechanism and their relationship with transition metal complexes has been considered. Macrocyclic ligands and their transition metal complexes depends upon the nature of reactants and the corresponding metal ion. The macrocyclic ligand are a growing class of compounds with varying chemistry a wide range of different molecular topologies and set of donor atoms. Aza type ligands appear as very promising to be used as antifertile, antibacterial, antifungal and other biological properties. Macrocyclic metal complexes play a central role in the construction of molecular materials, which display magnetic properties and find applications in material and supramolecular chemistry and biochemistry. It is believed that the present book will provide a succinct and clear introduction to synthesis, characterization and biological studies macrocyclic ligands with transition metal complexes that meets the needs of researchers at a variety of levels in several disciplines.

Synthesis and Complexation of Thia-aza Mixed-donor Ligands
Synthesis and Complexation of Thia-aza Mixed-donor Ligands

Author: Tia Louise Walker

Publisher:

Published: 2012

Total Pages: 287

ISBN-13:

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Following the structural characterization and analysis of Blue Copper Proteins (BCP's), macrocyclic ligands have attracted much interest as simple models for naturally occurring metal-macrocycle centers. Presented in this dissertation are the syntheses and characterization of small, simple organic analogs of BCP's. Chapter I of this work gives a brief literature review of Blue Copper Proteins, including their unique spectral characteristics. The synthesis and characterization of several linear and cyclic molecular analogs will be discussed including polythiaethers,3 polyazacycloalkanes,4 thia-aza5 and trithiaethers. The macrocyclic effect will be explained and why cyclic molecular analogs are of current interest. Presented in the second chapter are the syntheses of two 14-membered rings with a 2,3,2,3 altering carbon chain arrangement for 1,8-dithia-4,11-diazacyclotetradecane and 1,11-dithia-4,8-diazacyclotetradecane. The 1,8-dithia-4,11-diazacyclotetradecane is complexed to both Cu2+ and Cu+ and fully characterized using UV-Vis, EPR and CV. The 1,11-dithia-4,8-diazacyclotetradecane was synthesized for structural X-ray comparison of the Cu2+ metal ion. The 1,8-dithia-4,11-diazacyclotetradecane having two nitrogen atoms also makes it attractive for functionalization. Presented in the third chapter of this dissertation is the expansion of these ligands for use as cryptands. The syntheses of two cryptands are fully described and include crystallographic data. One of the cryptand ligands, 1,8-dithia-4,11,18,21-tetraazatricyclo[10.6.6]pentacosane-25-one was successfully complexed to Cu2+ and those results are also discussed. To further conclude this research is a pendant arm derivative and its synthesis. Each nitrogen atom of 1,8-dithia-4,11-diazacyclotetradecane is functionalized with a four carbon chain connecting to 1,4-diaza-7-thiacyclononane.

The Chemistry of Macrocyclic Ligand Complexes
The Chemistry of Macrocyclic Ligand Complexes

Author: Leonard F. Lindoy

Publisher: Cambridge University Press

Published: 1989-03-23

Total Pages: 281

ISBN-13: 052125261X

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This book contains an overview of complex formation by macrocyclic ligand systems. The study of macrocyclic chemistry represents a major area of activity which impinges on a range of other areas in both chemistry and biochemistry. The field has characteristically yielded many interesting and unusual compounds. The text discusses the structures and properties of macrocyclic compounds; the synthesis of macrocycles; polyether crown and related systems; metal-ion and molecular recognition (host-guest chemistry); as well as kinetic, thermodynamic and electrochemical aspects of a range of macrocyclic systems. A discussion of the different categories of naturally occurring macrocycles is also included. Specialist and non-specialist alike will find this a useful text. Apart from serving as a convenient reference for established workers in the field, it should also prove useful to new graduate students as well as to researchers from other areas who seek a general introduction to the subject. The topics discussed also provide a suitable basis for a senior undergraduate or graduate course in macrocyclic chemistry and inorganic complexes.