Supercomplexity in Interaction
Supercomplexity in Interaction

Author: Victoria Orange

Publisher: Springer Nature

Published: 2019-11-08

Total Pages: 139

ISBN-13: 3030280187

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This book aims to explore the supercomplexity of interaction and to suggest ways of teaching about this supercomplexity in various settings, including intercultural communication and language-learning. Using complex systems theory, the author argues that interaction is actually a supercomplex adaptive system which interconnects a number of different complex systems (the 4Es: Expression, Encounter, Education, Emotion) to give it meaning. She then draws on the concept of heartfulness to promote different ways of understanding and teaching the supercomplexity of interaction. This book will be of interest to language educators and students, as well as scholars of intercultural communication.

Methods and Paradigms in Education Research
Methods and Paradigms in Education Research

Author: Ling, Lorraine

Publisher: IGI Global

Published: 2016-10-31

Total Pages: 420

ISBN-13: 1522517391

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The tools used in data collection have the ability to influence the ways information is perceived and generated. Analyzing research processes is a concept that can be overlooked, though is as important as the information itself. Methods and Paradigms in Education Research addresses the innovative formulaic approaches taken in research to challenge their effectiveness. Featuring coverage on selection, forms, and analytical procedures of data, this publication is essential for researchers, students, and academicians seeking current information on understanding research methodology.

Macromolecular Protein Complexes II: Structure and Function
Macromolecular Protein Complexes II: Structure and Function

Author: J. Robin Harris

Publisher: Springer Nature

Published: 2020-01-14

Total Pages: 657

ISBN-13: 3030281515

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This book follows on from Volume 83 in the SCBI series (“Macromolecular Protein Complexes”), and addresses several important topics (such as the Proteasome, Anaphase Promoting Complex, Ribosome and Apoptosome) that were not previously included, together with a number of additional exciting topics in this rapidly expanding field of study. Although the first SCBI Protein Complex book focused on soluble protein complexes, the second (Vol. 87)addressed Membrane Complexes, and the third (Vol. 88) put the spotlight on Viral Protein and Nucleoprotein Complexes, a number of membrane, virus and even fibrillar protein complexes have been be considered for inclusion in the present book. A further book is also under preparation that follows the same pattern, in an attempt to provide a thorough coverage of the subject. Chapter 9 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Mitochondrial Oxidative Phosphorylation
Mitochondrial Oxidative Phosphorylation

Author: Bernhard Kadenbach

Publisher: Springer Science & Business Media

Published: 2012-06-23

Total Pages: 378

ISBN-13: 1461435730

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This book will describe the nuclear encoded genes and their expressed proteins of mitochondrial oxidative phosphorylation. Most of these genes occur in eukaryotic cells, but not in bacteria or archaea. The main function of mitochondria, the synthesis of ATP, is performed at subunits of proton pumps (complexes I, III, IV and V), which are encoded on mitochondrial DNA. The nuclear encoded subunits have mostly a regulatory function. However, the specific physiological functions of the nuclear encoded subunits of complexes I, III, IV, and V are mostly unknown. New data indicates that they are essential for life of higher organisms, which is characterized by an adult life without cell division (postmeiotic stage) in most tissues, after the juvenile growth. For complex IV (cytochrome c oxidase) some of these subunits occur in tissue-specific (subunits IV, VIa, VIb, VIIa, VIII), developmental-specific (subunits IV, VIa, and VIIa) as well as species-specific isoforms. Defective genes of some subunits were shown to induce mitochondrial diseases. Mitochondrial genes and human diseases will also be covered.

A Structural Perspective on Respiratory Complex I
A Structural Perspective on Respiratory Complex I

Author: Leonid Sazanov

Publisher: Springer Science & Business Media

Published: 2012-05-11

Total Pages: 281

ISBN-13: 9400741383

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The book contains chapters written by leaders in the research on the structure and function of respiratory complex I. It will provide a concise and authoritative summary of the current knowledge on complex I of respiratory chains. This enzyme is central to energy metabolism and is implicated in many human neurodegenerative diseases, as well as in aging. Until recently it was poorly understood on a structural level, and this book will provide a timely reference resource. Such a book was not published previously. The last time a minireview series on complex I were published was in 2001, and since then complex I field changed quite dramatically.

Understanding Learning at Work
Understanding Learning at Work

Author: David Boud

Publisher: Routledge

Published: 2012-10-12

Total Pages: 251

ISBN-13: 1134674139

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Work now invariably requires a continual focus on learning: to improve productivity, to enhance the flexibility of employees and to develop and transform organizations. This volume brings together leading experts from the United States, Britain, Australia and New Zealand to critically evaluate the current debates on workplace learning and to propose directions for future developments in both research and practice. Topics covered include: * expectations of learning at work into the twenty-first century * learning theories, practice and performance implications * the relationship between workplace learning and other forms of lifelong learning * the international developments in competency-based approaches to learning and assessment * the influence of language, power, culture and gender upon the 'construction' of learning. Topical and informative, this volume will be an invaluable resource for students and researchers of training, HRD, continuing and adult education.

Supporting Lifelong Learning: Organising learning
Supporting Lifelong Learning: Organising learning

Author: Roger Harrison

Publisher: Psychology Press

Published: 2002

Total Pages: 236

ISBN-13: 9780415259293

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This book looks at what types of learning environments promote lifelong learning, how they can be organized to support meaningful learning and what the implications of these shifts are for managers.

Emerging Methods and Paradigms in Scholarship and Education Research
Emerging Methods and Paradigms in Scholarship and Education Research

Author: Ling, Lorraine

Publisher: IGI Global

Published: 2019-08-30

Total Pages: 351

ISBN-13: 1799810038

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There is a renaissance in the use of the term “scholarship,” as it is being used to define areas of academic endeavour, describe academic work and achievements, and measure the quality of higher education. Although all academicians are required to engage in scholarship, it is difficult to navigate as there is a misunderstanding of this concept as new methods and approaches emerge. Emerging Methods and Paradigms in Scholarship and Education Research is an essential academic book that is designed to explain the areas of scholarship and their contemporary relationship to key components of academic work: research, teaching, service, and engagement. The chapter authors explore conceptions of scholarship, paradigms, and methods that fit a variety of contexts and needs. Highlighting a wide range of approaches from scientific realism and neo-positivism to interpretative, transformative, and pragmatic educational strategies and policy, this book is ideal for researchers, teachers, educational leaders, academicians, educational policymakers, and quality assurance agencies.

Computational Prediction of Protein Complexes from Protein Interaction Networks
Computational Prediction of Protein Complexes from Protein Interaction Networks

Author: Sriganesh Srihari

Publisher: Morgan & Claypool

Published: 2017-05-30

Total Pages: 297

ISBN-13: 1970001534

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Complexes of physically interacting proteins constitute fundamental functional units that drive almost all biological processes within cells. A faithful reconstruction of the entire set of protein complexes (the "complexosome") is therefore important not only to understand the composition of complexes but also the higher level functional organization within cells. Advances over the last several years, particularly through the use of high-throughput proteomics techniques, have made it possible to map substantial fractions of protein interactions (the "interactomes") from model organisms including Arabidopsis thaliana (a flowering plant), Caenorhabditis elegans (a nematode), Drosophila melanogaster (fruit fly), and Saccharomyces cerevisiae (budding yeast). These interaction datasets have enabled systematic inquiry into the identification and study of protein complexes from organisms. Computational methods have played a significant role in this context, by contributing accurate, efficient, and exhaustive ways to analyze the enormous amounts of data. These methods have helped to compensate for some of the limitations in experimental datasets including the presence of biological and technical noise and the relative paucity of credible interactions. In this book, we systematically walk through computational methods devised to date (approximately between 2000 and 2016) for identifying protein complexes from the network of protein interactions (the protein-protein interaction (PPI) network). We present a detailed taxonomy of these methods, and comprehensively evaluate them for protein complex identification across a variety of scenarios including the absence of many true interactions and the presence of false-positive interactions (noise) in PPI networks. Based on this evaluation, we highlight challenges faced by the methods, for instance in identifying sparse, sub-, or small complexes and in discerning overlapping complexes, and reveal how a combination of strategies is necessary to accurately reconstruct the entire complexosome.

Cytochrome Complexes: Evolution, Structures, Energy Transduction, and Signaling
Cytochrome Complexes: Evolution, Structures, Energy Transduction, and Signaling

Author: William A. Cramer

Publisher: Springer

Published: 2016-06-14

Total Pages: 763

ISBN-13: 9401774811

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An Introduction that describes the origin of cytochrome notation also connects to the history of the field, focusing on research in England in the pre-World War II era. The start of the modern era of studies on structure-function of cytochromes and energy-transducing membrane proteins was marked by the 1988 Nobel Prize in Chemistry, given to J. Deisenhofer, H. Michel, and R. Huber for determination of the crystal structure of the bacterial photosynthetic reaction center. An ab initio logic of presentation in the book discusses the evolution of cytochromes and hemes, followed by theoretical perspectives on electron transfer in proteins and specifically in cytochromes. There is an extensive description of the molecular structures of cytochromes and cytochrome complexes from eukaryotic and prokaryotic sources, bacterial, plant and animal. The presentation of atomic structure information has a major role in these discussions, and makes an important contribution to the broad field of membrane protein structure-function.