STEROID HORMONE ACTION AND CANCER- BASED ON THE PROCEEDINGS OF A SYMPOSIUM- DEPARTMENT OF POSTGRADUATE MEDICINE AND HEALTH PROFESSIONS EDUCATION, UNIVERSITY OF MICHIGAN.
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Published: 1977
Total Pages: 360
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DOWNLOAD EBOOKAuthor: National Library of Medicine (U.S.)
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Total Pages: 1568
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DOWNLOAD EBOOKFirst multi-year cumulation covers six years: 1965-70.
Author: K. Menon
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 231
ISBN-13: 146842601X
DOWNLOAD EBOOKThis volume is an outgrowth of a symposium held at the University of Michigan, Ann Arbor, Michigan, October 27-29, 1975. This symposium was organized to bring together basic scientists and clinicians for the purpose of exchanging new ideas and the latest information in the area of Steroid Hormone Action and Cancer. The design of the symposium included both formal plenary sessions and informal roundtable discussion groups, the chapters of this volume being drawn primarily from these proceedings. During the last quarter of a century considerable progress has been made toward understanding the molecular mechanisms in volved in steroid hormone action. It now appears that the mechan sim of action of the four major classes of steroid hormones is qualitatively similar. Research during the past decade has demonstrated steroid hormone receptors in a variety of normal and neoplastic tissues. Receptor-containing neoplasms have been shown to be hormone-dependent and undergo regression when treated with hormone antagonists. Natural and synthetic steroids also have been employed for many years to successfully treat various types of cancer, for example: estrogens, androgens and progestagens for breast cancer; estrogens and progestagens for prostatic carcinoma; progestagens for endometrial carcinoma; and corticoids for leu kemias. All of these neoplasms have now been found to possess receptors for the steroids empirically used in their treatment.
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Published: 1976
Total Pages: 182
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DOWNLOAD EBOOKAuthor: Gregory Pincus
Publisher: Academic Press
Published: 2013-09-17
Total Pages: 547
ISBN-13: 1483270572
DOWNLOAD EBOOKBiological Activities of Steroids in Relation to Cancer covers the proceedings of the conference sponsored by the Cancer Chemotherapy National Service Center, National Cancer Institute, National Institutes of Health, and the U. S. Department of Health, Education and Welfare. The text focuses on the influence of steroids on medical approaches to the cure of cancer, including steroid chemistry, estrogen metabolism, and mammary cancer. The selection first offers information on steroids growth and cancer, advances in steroid chemistry, and the physiology and pharmacology of steroids affecting tumor growth. Discussions focus on rapid development of mammary cancer, pituitary functions, androgens, estrogens, and progestins. The book also ponders on the binding of steroid hormones by plasma proteins; the effects of steroids on the levels of the plasma 17-hydroxycorticosteroids and the serum protein-bound iodine; and the metabolism of dehydroisoandrosterone. The text evaluates studies on estrogen metabolism, biochemical parameters of estrogen action, and enzymatic transport of hydrogen by estrogenic hormones. The manuscript also elaborates on the fate of steroid estrogens in target tissues, effect of steroids on calcium dynamics, and steroids and experimental mammary cancer. The selection is a valuable source of information for readers interested in the use of steroids in treating cancer.
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Published: 1977
Total Pages: 1028
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Published: 1976
Total Pages: 0
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DOWNLOAD EBOOKAuthor: K. Menon
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Published: 2014-01-15
Total Pages: 196
ISBN-13: 9781468426021
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