Stem Cells in Oral Cavity: From Development to Regeneration
Author: Mikihito Kajiya
Publisher: Frontiers Media SA
Published: 2022-02-22
Total Pages: 178
ISBN-13: 2889744760
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Regenerative Dentistry
Author: Mona Marei
Publisher: Springer Nature
Published: 2022-06-01
Total Pages: 164
ISBN-13: 3031025814
DOWNLOAD EBOOKDental caries, periodontitis, tooth loss, and bone resorption are considered prevalent health problems that have direct affect on the quality of life. While, advances in stem cell biology and biotechnology have sparked hope for devastating maladies, such as diabetes, cardiovascular diseases, etc., it also provides a strategy of regenerative therapy for dental tissues. From the prospective of tissue engineering, it is of utmost importance to understand and emulate the complex cell interactions that make up a tissue or organ. Unlike other tissues in the body, dental tissues are unique in their development, function, and even in their maintenance throughout life. The harmonized stimulations of biology and mechanical regulators to promote cellular activities have matured our understanding of the value of regenerative therapy of dental tissue versus the reparative treatment. In this book, we review the current knowledge available to regenerate alveolar bone, periodontal structure, and pulp/dentin complex. The book provides researchers with detailed information about development and functional characteristics of the dental unit with detailed protocols covering a comprehensive range of various approaches to engineer dental tissues: to use isolated cells or cell substitutes as cellular replacement, to use acellular biomaterials capable of inducing tissue regeneration, and/or to use a combination of cells, biomaterial and growth factors. We are well aware, with the concept changes in the field toward in-vitro biomimetics of in-vivo tissue development. The theoretical frame work integrating these concepts of developmental biology and developmental engineering is yet to be emphasized and implemented. Until this happens, we consider this book of regenerative dentistry as a call for scientists to achieve, researchers to innovate, practitioners to apply, and students to learn the art and science of regenerative therapy in dentistry. Table of Contents: Introduction to Regenerative Dentistry / Tissue Engineering Alveolar Bone / Tissue Engineering of the Periodontal Tissues / Dynamics for Pulp-Dentin Tissue Engineering in Operative Dentistry
Dental Stem Cells: Regenerative Potential
Author: Barbara Zavan
Publisher: Humana Press
Published: 2016-07-25
Total Pages: 288
ISBN-13: 3319332996
DOWNLOAD EBOOKThis book focuses on the basic aspects of dental stem cells (DSCs) as well as their clinical applications in tissue engineering and regenerative medicine. It opens with a discussion of classification, protocols, and properties of DSCs and proceeds to explore DSCs within the contexts of cryopreservation; epigenetics; pulp, periodontal, tooth, bone, and corneal stroma regeneration; neuronal properties, mesenchymal stem cells and biomaterials; and as sources of hepatocytes for liver disease treatment. The fifteen expertly authored chapters comprehensively examine possible applications of DSCs and provide invaluable insights into mechanisms of growth and differentiation. Dental Stem Cells: Regenerative Potential draws from a wealth of international perspectives and is an essential addition to the developing literature on dental stem cells. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is indispensable for biomedical researchers interested in bioengineering, dentistry, tissue engineering, regenerative medicine, cell biology and oncology.
Regenerative Medicine in Otolaryngology
Author: Juichi Ito
Publisher: Springer
Published: 2015-05-07
Total Pages: 236
ISBN-13: 4431548564
DOWNLOAD EBOOKThis book describes an exciting new movement using regenerative medicine to treat patients with otolaryngological diseases. The emerging field of regenerative medicine uses tissue engineering, which combines medicine and engineering not only to treat the diseases themselves but also to enable recovery of the function of affected areas. As otolaryngology covers wide regions, including many diseases of the head and neck, the book is divided into sections, each corresponding to a different anatomical structure — the ear, nose, oral cavity, pharynx, larynx and head and neck. The structural developments of each region, the underlying mechanisms of diseases specific to these regions, their experimental models and proposals for new regenerative treatment are all discussed in detail. The various diseases and symptoms considered in the book include inner ear and middle ear diseases, rhinitis, nasal sinusitis and otolaryngological cancers. To date there have been few clinical studies reporting regenerative medical applications in the field of otolaryngology, but in this volume leading authors present the latest research findings to help provide new therapies for patients in the future. This state-of-the-art information makes the book a valuable professional reference work for all doctors and researchers who focus on regenerative treatments in the field of otolaryngology and neuroscience.
Oral Wound Healing
Author: Hannu Larjava
Publisher: John Wiley & Sons
Published: 2012-05-15
Total Pages: 433
ISBN-13: 0813804817
DOWNLOAD EBOOKOral Wound Healing: Cell Biology and Clinical Management brings experts from around the world together to provide an authoritative reference on the processes, principles and clinical management of wound healing in the oral mucosa. Promoting a thorough understanding of current research on the topic, this new resource draws together thinking on the basic biological processes of wound healing in the oral environment, as well as providing more detailed information and discussion on processes such as inflammation, reepithelialization and angiogenesis. Beyond this, the book goes on to examine topics pertinent to the effective clinical management of oral wound healing, bringing together chapters on large dento-facial defects, dental implants, periodontal regeneration, and pulp healing.An essential synthesis of current research and clinical applications, Oral Wound Healing will be an indispensable resource for dental specialists, oral and maxillofacial surgeons as well as researchers in oral medicine and biology.
Organ Tissue Engineering
Author: Daniel Eberli
Publisher: Springer
Published: 2021-04-22
Total Pages: 0
ISBN-13: 9783030442101
DOWNLOAD EBOOKThe notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.
Ten Cate's Oral Histology
Author: Antonio Nanci
Publisher: Elsevier Health Sciences
Published: 2008-01-01
Total Pages: 432
ISBN-13: 032304557X
DOWNLOAD EBOOKAccompanying CD-ROM contains ... "150 color images with legends, 472 book figures with legends, 438 multiple choice test questions, and 119 interactive drag-and-drop exercises." -- from CD-ROM Welcome screen.
Injectable Biomaterials
Author: Brent Vernon
Publisher: Elsevier
Published: 2011-01-24
Total Pages: 425
ISBN-13: 0857091379
DOWNLOAD EBOOKNovel injectable materials for non-invasive surgical procedures are becoming increasingly popular. An advantage of these materials include easy deliverability into the body, however the suitability of their mechanical properties must also be carefully considered. Injectable biomaterials covers the materials, properties and biomedical applications of injectable materials, as well as novel developments in the technology.Part one focuses on materials and properties, with chapters covering the design of injectable biomaterials as well as their rheological properties and the mechanical properties of injectable polymers and composites. Part two covers the clinical applications of injectable biomaterials, including chapters on drug delivery, tissue engineering and orthopaedic applications as well as injectable materials for gene delivery systems. In part three, existing and developing technologies are discussed. Chapters in this part cover such topics as environmentally responsive biomaterials, injectable nanotechnology, injectable biodegradable materials and biocompatibility. There are also chapters focusing on troubleshooting and potential future applications of injectable biomaterials.With its distinguished editor and international team of contributors, Injectable biomaterials is a standard reference for materials scientists and researchers working in the biomaterials industry, as well as those with an academic interest in the subject. It will also be beneficial to clinicians. - Comprehensively examines the materials, properties and biomedical applications of injectable materials, as well as novel developments in the technology - Reviews the design of injectable biomaterials as well as their rheological properties and the mechanical properties of injectable polymers and composites - Explores clinical applications of injectable biomaterials, including drug delivery, tissue engineering, orthopaedic applications and injectable materials for gene delivery systems
Progenitor and Stem Cell Technologies and Therapies
Author: Anthony Atala
Publisher: Elsevier
Published: 2012-03-15
Total Pages: 561
ISBN-13: 0857096079
DOWNLOAD EBOOKProgenitor and stem cells have the ability to renew themselves and change into a variety of specialised types, making them ideal materials for therapy and regenerative medicine. Progenitor and stem cell technologies and therapies reviews the range of progenitor and stem cells available and their therapeutic application.Part one reviews basic principles for the culture of stem cells before discussing technologies for particular cell types. These include human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells. Part two discusses wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies. The final part of the book considers the therapeutic use of stem and progenitor cells. Chapters review the use of adipose tissue-derived stem cells, umbilical cord blood (UCB) stem cells, bone marrow, auditory and oral cavity stem cells. Other chapters cover the use of stem cells in therapies in various clinical areas, including lung, cartilage, urologic, nerve and cardiac repair.With its distinguished editor and international team of contributors, Progenitor and stem cell technologies and therapies is a standard reference for both those researching in cell and tissue biology and engineering as well as medical practitioners investigating the therapeutic use of this important technology. - Reviews the range of progenitor and stem cells available and outlines their therapeutic application - Examines the basic principles for the culture of stem cells before discussing technologies for particular cell types, including human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells - Includes a discussion of wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies
Oral Histology
Author: Arnold Richard Ten Cate
Publisher: St. Louis ; Toronto : Mosby
Published: 1998
Total Pages: 526
ISBN-13:
DOWNLOAD EBOOKDental students receive the most up-to-date information about oral histology, physiology, embryology, and postnatal development from ORAL HISTOLOGY: Development, Structure, and Function. This leading text features in-depth explanations with over 870 illustrations for a clear understanding of histologic principles. For the first time, this text showcases 48 color photographs. Every chapter includes a "Questions and Controversies" box that addresses current trends and research. A list of hand-picked recommended readings, and updated illustrations and references are also provided. It's the text every dental student needs to build a solid foundation for clinical practice. * Authoritative and up to date for the latest developments in oral histology. * Clearly written, consistent and well illustrated to facilitate learning. * Contributed by a renowned panel of histologists and oral biologists who bring years of clinical expertise and teaching skills to the textbook. * Thoroughly illustrated with high quality photographs and micrographs, and a 48-plate color section. NEW TO THIS EDITION: * 48 color plates cross referenced throughout the text provide brilliant reproduction and aid in recognition. * Reorganization of materials streamline the text and focus on the curriculum used in most dental schools. * New Questions and Controversies boxes provide insight on current research and trends, foster class discussion, and provide avenues for further research. * Hand picked Suggested Readings guide students to the most valuable references used throughout the text.
