Stem Cells in Animal Species: From Pre-clinic to Biodiversity
Stem Cells in Animal Species: From Pre-clinic to Biodiversity

Author: Tiziana A.L. Brevini

Publisher: Springer

Published: 2014-08-29

Total Pages: 192

ISBN-13: 331903572X

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This volume focuses on stem cell research and disease modeling in non-murine species. The book is divided into three parts: Stem Cells for Pre-Clinical Models, Stem Cells in Non-Conventional Species, and Stem Cell Banking for the Future. The first section presents an overview of the different pre-clinical stem cell models recently created in animal species, including the porcine model for heart failure, iPSC in large animal species, Duchenne muscular dystrophy and canine embryo-derived stem cells and modeling for human diseases. This section also discusses the potential advantages and applications of these models. The second part of this book describes recent efforts to use stem cells for preserving endangered species, including the snow leopard and coral reefs. From this perspective, stem cells are an invaluable tool to preserve bio-diversities. Frozen cells and gametes can be obtained from animals at risk of extinction and even from microorganisms and corals suffering from heavy changes in the eco-system; this may allow the cultivation of a generation of stem cell lines and represents an exciting opportunity to support and ensure the conservation of precious varieties of living creatures. This discussion leads easily into the third section, which discusses stem cell banking as a way of safeguarding these endangered species.

Big Cats
Big Cats

Author: A. B. Shrivastav

Publisher: BoD – Books on Demand

Published: 2017-12-20

Total Pages: 144

ISBN-13: 9535136836

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In this book, the editors have reviewed the scientific articles from diverse group of scientists from all over the world who are actively participating in the wildlife conservation. Some of the important divisions incorporated in the book are conservation and population genetics, biodiversity, ecology, conservation physiology and evolution of big cats. The different chapters written by eminent scientists with their experience will provide an overview of the current information on conservation strategies and survival of big cats in different geographical zones around the world. The articles will also provide valuable information, on both free range and captive felines, to understand the present and future of the majestic species. The book will be useful to biologists, veterinary students, wildlife managers, researchers and also wildlife conservationists.

Guide for the Care and Use of Laboratory Animals
Guide for the Care and Use of Laboratory Animals

Author: National Research Council

Publisher: National Academies Press

Published: 2011-01-27

Total Pages: 246

ISBN-13: 0309154006

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A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Biodiversity and Human Health
Biodiversity and Human Health

Author: Francesca Grifo

Publisher: Island Press

Published: 1997-02-01

Total Pages: 0

ISBN-13: 9781559635004

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The implications of biodiversity loss for the global environment have been widely discussed, but only recently has attention been paid to its direct and serious effects on human health. Biodiversity loss affects the spread of human diseases, causes a loss of medical models, diminishes the supplies of raw materials for drug discovery and biotechnology, and threatens food production and water quality. Biodiversity and Human Health brings together leading thinkers on the global environment and biomedicine to explore the human health consequences of the loss of biological diversity. Based on a two-day conference sponsored by the National Institutes of Health, the National Science Foundation, and the Smithsonian Institution, the book opens a dialogue among experts from the fields of public health, biology, epidemiology, botany, ecology, demography, and pharmacology on this vital but often neglected concern. Contributors discuss the uses and significance of biodiversity to the practice of medicine today, and develop strategies for conservation of these critical resources. Topics examined include: the causes and consequences of biodiversity loss emerging infectious diseases and the loss of biodiversity the significance and use of both prescription and herbal biodiversity-derived remedies indigenous and local peoples and their health care systems sustainable use of biodiversity for medicine an agenda for the future In addition to the editors, contributors include Anthony Artuso, Byron Bailey, Jensa Bell, Bhaswati Bhattacharya, Michael Boyd, Mary S. Campbell, Eric Chivian, Paul Cox, Gordon Cragg, Andrew Dobson, Kate Duffy-Mazan, Robert Engelman, Paul Epstein, Alexandra S. Fairfield, John Grupenhoff, Daniel Janzen, Catherine A. Laughin, Katy Moran, Robert McCaleb, Thomas Mays, David Newman, Charles Peters, Walter Reid, and John Vandermeer. The book provides a common framework for physicians and biomedical researchers who wish to learn more about environmental concerns, and for members of the environmental community who desire a greater understanding of biomedical issues.

Encyclopedia of Stem Cell Research
Encyclopedia of Stem Cell Research

Author:

Publisher: SAGE

Published: 2008

Total Pages: 953

ISBN-13: 141295908X

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"Provides an understanding of the basic concepts in stem cell biology and addresses the politics, ethics, and challenges currently facing the field"--From publisher description.

Stem Cells and Regenerative Medicine
Stem Cells and Regenerative Medicine

Author: Walter C. Low

Publisher: World Scientific

Published: 2008

Total Pages: 571

ISBN-13: 9812775773

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The commercialization of biotechnology has resulted in an intensive search for new biological resources for the purposes of increasing food productivity, medicinal applications, energy production, and various other applications. Although biotechnology has produced many benefits for humanity, the exploitation of the planet's natural resources has also resulted in some undesirable consequences such as diminished species biodiversity, climate change, environmental contamination, and intellectual property right and patent concerns.This book discusses the role of biological, ecological, environmental, ethical, and economic issues in the interaction between biotechnology and biodiversity, using different contexts. No other book has discussed all of these issues in a comprehensive manner. Of special interest is their impact when biotechnology is shared between developed and developing countries, and the lack of recognition of the rights of indigenous populations and traditional farmers in developing countries by large multinational corporations.

Sustaining Life
Sustaining Life

Author: Eric Chivian

Publisher: Oxford University Press, USA

Published: 2008-05-15

Total Pages: 576

ISBN-13:

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Edited and written by Harvard Medical School physicians Eric Chivian and Aaron Bernstein, Sustaining Life presents a comprehensive--and sobering--view of how human medicines, biomedical research, the emergence and spread of infectious diseases, and the production of food, both on land and in the oceans, depend on on the earth's disappearaing biodiversity. With a foreword by E.O. Wilson and a prologue by Kofi Annan, and more than 200 poignant color illustrations, Sustaining Life contributes essential perspective to the debate over how humans affect biodiversity and a compelling demonstration of the human health costs.

Stem Cells Handbook
Stem Cells Handbook

Author: Stewart Sell

Publisher: Springer Science & Business Media

Published: 2013-08-16

Total Pages: 524

ISBN-13: 1461476968

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This book discusses critical areas of progress in stem cell research, including the most recent research and applications of pluripotent embryonic cells, induced pluripotent cells, oligopotent tissue stem cells and cancer stem cells. The text covers basic knowledge of stem cell biology, stem cell ethics, development of techniques for applying stem cell therapy, the technology of obtaining appropriate cells for transplantation as well as the role of stem cells in cancer and how therapy may be directed to cancer stem cells. This new volume is essential reading for all scientists currently in the field or allied research areas, and those for those graduate students who envision a career in stem cells.

Chimera Research
Chimera Research

Author: Insoo Hyun

Publisher: Humana

Published: 2020-08-14

Total Pages: 234

ISBN-13: 9781493995264

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This volume addresses challenging new questions surrounding stem cell-based chimera research. This book is organized into three parts: Part One provides readers with a summary of different human donor cell types. The chapters in this section discuss ways to evaluate new types of pluripotent stem cells; the derivation of naïve and primed pluripotent stem cells from mouse preimplantation embryos; and the ethical and regulatory complexities of informed consent for the procurement of somatic cells. Part Two discusses methods for generating chimeras. The chapters here look at chick models and human-chick organizer grafts; generating human-pig interspecies chimeras; and techniques for transplanting mouse neural stem cells into a mouse disease model for stroke. Part Three concludes the book with a look at ongoing ethical controversies and new scientific directions. Chapters in this part cover the ethics of crossing the xenobarrier; animal welfare; experimentation with spermatogonial stem cells; and cautious approaches to human-monkey chimera studies to further understand complex human brain disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Chimera Research: Methods and Protocols is a valuable resource for scientists interesting in using chimeras as a research tool while also taking into consideration their complex ethical scopes.