The book concentrates on powder flow properties, their measurement and applications. These topics are explained starting from the interactions between individual particles up to the design of silos. A wide range of problems are discussed – such as flow obstructions, segregation, and vibrations. The goal is to provide a deeper understanding of the powder flow, and to show practical solutions.
Powders and bulk solids, handled widely in the chemical, pharmaceutical, agriculture, smelting, and other industries present unique fire, explosion, and toxicity hazards. Indeed, substances which are practically inert in consolidated form may become quite hazardous when converted to powders and granules. The U.S. Chemical Safety and Hazard Investigation Board is currently investigating dust explosions that occured in 2003 at WestPharma, CTA Acoustics, and Hayes-Lemmerz, and is likely to recommend that companies that handle powders or whose operations produce dust pay more attention to understanding the hazards that may exist at their facility. This new CCPS guidelines book will discuss the types of hazards that can occur in a wide range of process equipment and with a wide range of substances, and will present measures to address these hazards.
In recent years, there has been a dramatic increase in grain-based fuel ethanol production in North America and around the world. Whether such production will result in a net energy gain or whether this is sustainable in the long term is under debate, but undoubtedly millions of tons of non-fermented residues are now produced annually for global tr
Laser powder bed fusion of metals is a technology that makes use of a laser beam to selectively melt metal powder layer-by-layer in order to fabricate complex geometries in high performance materials. The technology is currently transforming aerospace and biomedical manufacturing and its adoption is widening into other industries as well, including automotive, energy, and traditional manufacturing. With an increase in design freedom brought to bear by additive manufacturing, new opportunities are emerging for designs not possible previously and in material systems that now provide sufficient performance to be qualified in end-use mission-critical applications. After decades of research and development, laser powder bed fusion is now enabling a new era of digitally driven manufacturing. Fundamentals of Laser Powder Bed Fusion of Metals will provide the fundamental principles in a broad range of topics relating to metal laser powder bed fusion. The target audience includes new users, focusing on graduate and undergraduate students; however, this book can also serve as a reference for experienced users as well, including senior researchers and engineers in industry. The current best practices are discussed in detail, as well as the limitations, challenges, and potential research and commercial opportunities moving forward. - Presents laser powder bed fusion fundamentals, as well as their inherent challenges - Provides an up-to-date summary of this advancing technology and its potential - Provides a comprehensive textbook for universities, as well as a reference for industry - Acts as quick-reference guide
Powder flow has attracted increased attention in recent years as novel formulated and functional products are being developed in powder forms, particularly in pharmaceutical and high value additive manufacturing industries. This book meets a need for a truly integrated modern treatment of dry powder flow, covering theory, robust characterisation techniques, modelling tools and applications. Written by leaders in the field, the book opens by introducing the wide range of powder processing problems faced by industry, the complexities of powders and the myriad of ways their flow behaviour can be characterised. The authors then move on, with contributions from experts, to describe fundamental properties that can be measured, defining the states of stress and shear rate and the considerations that need to be taken account. By providing a comprehensive treatment of all available characterisation techniques, as well as various modelling tools, the reader obtains a clear, practical overview. Case studies and applications connect theory to practical examples across a broad range of industries. This book stands out by not only providing the reader with guidance on what to measure but also how to interpret results, ensuring this is an invaluable text for anyone working on powder flow in the chemical, pharmaceutical and manufacturing industries, as well as students and researchers across chemical and process engineering disciplines.
Segregation in Vibrated Granular Systems explains the individual mechanisms that influence the segregation of granular media under vibration, along with their interactions. Drawing on research from a wide range of academic disciplines, the book focuses on vibrated granular systems that are used in industry, providing a guide that will solve practical problems and help researchers. The applications of vibration-based segregation in industries, including pharmaceuticals, mining, food and chemical processing are all investigated with appropriate examples. In addition, relevant theory behind the behavior of granular media and segregation processes is explained, along with investigations of the technologies and techniques used. - Analyzes all phenomena involved in the vibration-based segregation of bulk solids, including those relating to size, material properties and shape - Explores how different segregation mechanisms interact - Compares different technologies for investigating granular media, including PIV, MRI and X-ray tomography - Explains how to use computational techniques to model the behavior of granular media, including DM, CFD and FEM
This edited volume brings together the expertise of numerous specialists on the topic of particles – their physical, chemical, pharmacological and toxicological characteristics – when they are a component of pharmaceutical products and formulations. The book discusses in detail properties such as the composition, size, shape, surface properties and porosity of particles with respect to how they impact the formulations and products in which they are used and the effective delivery of pharmaceutical active ingredients. It considers all dosage forms of pharmaceuticals involving particles, from powders to tablets, creams to ointments, and solutions to dry-powder inhalers, also including the latest nanomedicine products. Further, it discusses examples of particle toxicity, as well as the important subject of pharmaceutical industry regulations, guidelines and legislation. The book is of interest to researchers and practitioners who work on testing and developing pharmaceutical dosage and delivery systems.
