This publication was developed by an international group of experts as an integral part of the IAEA's efforts to contribute to the transfer of technology and knowledge in nutrition. Its aim is to assist Member States in their efforts to combat malnutrition by facilitating the use of relevant nuclear techniques. The stable (non-radioactive) isotope technique has been developed to assess intake of human milk in breastfed infants. The practical application of the stable isotope technique, based on analysis of deuterium by Fourier transform infrared spectrometry (FTIR), is presented in this book.
This publication was developed by an international group of experts as an integral part of the IAEAs efforts to contribute to the transfer of technology and capacity building in this field in order to assist Member States in their efforts to improve the nutrition and health of the most vulnerable population groups, infants and young children. The book provides practical information on the assessment of body composition from birth up to two years of age and is intended for nutritionists, pediatricians and other health professionals. The body composition assessment techniques included in this publication were selected as methodologies with the highest potential for standardization globally based on considerations such as access to equipment, cost and the training needs of staff and include stable isotope dilution for total body water assessment, as well as dual energy X ray absorptiometry and air displacement plethysmography. In addition, the importance of standardization of anthrop
Human milk is considered the biologic norm for feeding the human infant during the first 6 months of life, and it is a preferred food from 6 to 12 months. It is a complex food and exerts its biologic effects well beyond its known nutritional value; however, human milk composition and the complexity of its composition is not wholly known or understood. Thus, defining the composition of milk, as well as both the individual and combined effects of milk components and the volume consumed on infant growth and development, is central to optimizing infant health. Furthermore, defining human milk composition, volume, and the myriad factors that influence milk components is needed for developing future Dietary Reference Intake (DRI) standards for nutrient intakes during the first 12 months of life. Scanning for New Evidence on the Nutrient Content of Human Milk examines the new and emerging evidence describing the nutrient content of human milk as well as the volume of milk consumed, both of which are needed to understand nutrient consumption by healthy breastfed infants. An evidence scan approach was used to summarize the status of the published literature on the nutrient content of human milk and to identify new evidence on nutrients in human milk that could inform the need for a systematic review as a component of the DRI process.
Infant formulas are unique because they are the only source of nutrition for many infants during the first 4 to 6 months of life. They are critical to infant health since they must safely support growth and development during a period when the consequences on inadequate nutrition are most severe. Existing guidelines and regulations for evaluating the safety of conventional food ingredients (e.g., vitamins and minerals) added to infant formulas have worked well in the past; however they are not sufficient to address the diversity of potential new ingredients proposed by manufacturers to develop formulas that mimic the perceived and potential benefits of human milk. This book, prepared at the request of the Food and Drug Administration (FDA) and Health Canada, addresses the regulatory and research issues that are critical in assessing the safety of the addition of new ingredients to infants.
This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.
Human milk is uniquely tailored to meet infants’ specific nutritional requirements. However, it is more than just “milk”. This dynamic and bioactive fluid allows mother–infant signalling over lactation, guiding the infant in the developmental and physiological processes. It exerts protection and life-long biological effects, playing a crucial role in promoting healthy growth and optimal cognitive development. The latest scientific advances have provided insight into different components of human milk and their dynamic changes over time. However, the complexity of human milk composition and the synergistic mechanisms responsible for its beneficial health effects have not yet been unravelled. Filling this knowledge gap will shed light on the biology of the developing infant and will contribute to the optimization of infant feeding, particularly that of the most vulnerable infants. Greater understanding of human milk will also help in elucidating the best strategies for its storage and handling. The increasing knowledge on human milk’s bioactive compounds together with the rapidly-advancing technological achievements will greatly enhance their use as prophylactic or therapeutic agents. The current Special Issue aims to welcome original works and literature reviews further exploring the complexity of human milk composition, the mechanisms underlying the beneficial effects associated with breastfeeding, and the factors and determinants involved in lactation, including its promotion and support.
What information is available to inform the planning of a nutrition research agenda for the United States and Canada? This question provided the backdrop for the Dietary Reference Intakes Research Synthesis project undertaken by the Food and Nutrition Board of the Institute of Medicine (IOM) of the National Academies. The Dietary Reference Intakes (DRIs) are quantitative reference values for recommended intakes and tolerable upper intake levels for a range of nutrients. They are used widely by dietitians in individual counseling, by federal nutrition officials in program and policy development, and by the nutrition research and education communities in government, academia, and industry. Between 1997 and 2005, the IOM published a series of six DRI reports covering a total of 45 nutrients, energy, and other food components. The IOM also issued two reports describing ways to apply the DRIs in assessment and planning. Together, these eight reports contain more than 450 research recommendations and thus a wealth of information pertinent to a nutrition research agenda. To make the recommendations more accessible, the Food and Nutrition Board undertook a project with two major elements: (1) the development of a searchable database of all the DRI research recommendations, and (2) the Dietary Reference Intakes Research Synthesis Workshop, held June 7-8, 2006, which was designed to provide a venue for hearing and discussing experts' perspectives on the research recommendations identified in the DRI reports. Two members of the workshop planning group-Drs. John W. Suttie and Susan J. Whiting-moderated the DRI Research Synthesis Workshop. After an overview and demonstration of the DRI Research Synthesis Database, panels of experts addressed DRI research recommendations related to each of the six DRI nutrient reports, the two DRI applications reports, and three cross-cutting topics: (1) setting DRIs for children, (2) Tolerable Upper Intake Levels, and (3) relevant new and underutilized research techniques. This report is a summary of the workshop presentations and discussions.
George Bowering and Greg Curnoe became friends in London, Ontario, in 1966. Bowering was a 30-year-old poet and university student and Curnoe was a 29-year-old painter who had dropped out of art school in Toronto to return to his place of birth. Their art was in its youth, their eyes and ears were wide open and their stomachs could withstand pots and pots of strong, black coffee. For 26 years they grew up parallel, inside each other’s work. Greg Curnoe was killed on his bicycle late in 1992, struck down in the middle of his bright career. This memoir was begun in London, Ontario, on November 20, 1992.
