Sleep-Wake Neurobiology and Pharmacology
Sleep-Wake Neurobiology and Pharmacology

Author: Hans-Peter Landolt

Publisher: Springer Nature

Published: 2019-09-03

Total Pages: 481

ISBN-13: 3030112721

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This volume connects current ideas and concepts about sleep functions and circadian rhythms with the search for novel target-selective sleep-wake therapeutics. To do so, it provides a timely, state-of-the-art overview of sleep-wake mechanisms in health and disease, ongoing developments in drug discovery, and their prospects for the clinical treatment of sleep-disordered patients. It particularly focuses on the concept that sleep and wakefulness mutually affect each other, and the future therapeutic interventions with either sleep- or wake-promoting agents that are expected to not only improve the quality of sleep but also the waking behavior, cognition, mood and other sleep-associated physiological functions. The chapter 'Sleep Physiology, Circadian Rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics' available open access under a CC BY 4.0 license at link.springer.com

The Pharmacology of Sleep
The Pharmacology of Sleep

Author: Anthony Kales

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 603

ISBN-13: 3642578365

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A review of the current state of the clinical and basic science of the pharmacology of sleep. The information provided ranges from a historical perspective to current concepts of sleep mechanisms, including the interaction between pharmacology and sleep-wake regulation and between chronopahrmacology and sleep-wake rhythms. For the first time in one single volume, both the basic mechanisms of sleep, and the basic and clinical aspects of the pharmacology of sleep are dealt with in a thorough, comprehensive and authoritative manner. The chapters, written by the foremost scientific authorities in this field, integrate the latest information on the basic mechanisms of drugs as they relate to their effects on sleep.

The Pharmacology of Sleep
The Pharmacology of Sleep

Author: Anthony Kales

Publisher: Springer

Published: 2011-09-27

Total Pages: 583

ISBN-13: 9783642578373

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A review of the current state of the clinical and basic science of the pharmacology of sleep. The information provided ranges from a historical perspective to current concepts of sleep mechanisms, including the interaction between pharmacology and sleep-wake regulation and between chronopahrmacology and sleep-wake rhythms. For the first time in one single volume, both the basic mechanisms of sleep, and the basic and clinical aspects of the pharmacology of sleep are dealt with in a thorough, comprehensive and authoritative manner. The chapters, written by the foremost scientific authorities in this field, integrate the latest information on the basic mechanisms of drugs as they relate to their effects on sleep.

Sleep and Sleep Disorders:
Sleep and Sleep Disorders:

Author: Malcolm Lader

Publisher: Springer Science & Business Media

Published: 2009-11-06

Total Pages: 319

ISBN-13: 0387276823

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Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psychopharmacology. This timely book serves to present updated information about the neuropsychopharmacology of sleep as this field enters mainstream psychiatry, neurology and medicine This volume has assembled articles that summarize and review carefully, a chosen selection of the latest discoveries concerning sleep medicine, sleep physiology and sleep pharmacology. Outstanding contributions have been sought from acknowledged experts in their respective fields. The goal of the volume is to present the more recent developments and advances in the fields of sleep and neuropsychopharmacology, as well as to provide a context for considering them both in depth and from multidisciplinary perspectives. This volume brings together the collective expertise of clinicians and basic researchers who represent a range of interests in neuroscience, neuropharmacology, sleep physiology, and biological rhythms. Presenting a thoughtful balance of basic experimental and clinical facts and viewpoints, this book will serve as a foundation for understanding, and ultimately treating, sleep disorders.

The Gating and Maintenance of sleep and Wake: New Circuits and Insights
The Gating and Maintenance of sleep and Wake: New Circuits and Insights

Author: Michael Lazarus

Publisher: Frontiers Media SA

Published: 2020-10-09

Total Pages: 299

ISBN-13: 2889660613

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle
The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle

Author: Eric Murillo-Rodriguez

Publisher: Academic Press

Published: 2019-03-26

Total Pages: 220

ISBN-13: 0128167424

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The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle provides the first comprehensive overview on the molecular methodologies used to evaluate sleep while also examining the cellular, biochemical, genetic, and therapeutic aspects of the sleep-wake cycle. There have been profound changes in the landscape of approaches to the study of sleep – mainly in the areas of molecular biology and molecular techniques. With this great focus on using multidisciplinary molecular methods, chapters address significant advances in the molecular mechanisms underlying sleep and the techniques researchers use to study this phenomenon. Written by world-leading experts in the area, this book is of great interest to researchers working in the sleep field and to anyone interested in one of the most mysterious phenomena in science – why we sleep and why we cannot survive without it. Reviews the neurobiological and cellular mechanisms of the sleep-wake cycle Provides the implications of sleep in health and disease Contrasts different techniques to study molecular mechanisms Contains case studies to better illustrate points Covers sleep disturbance and health problems involved in sleep Includes chapters on the ontogeny of sleep, along with multiple mechanisms for sleep generation

Neurobiology of Sleep and Memory
Neurobiology of Sleep and Memory

Author: James McGaugh

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 471

ISBN-13: 0323149154

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Neurobiology of Sleep and Memory is the textual result of a symposium regarding the basic neurological processes in the storage of different kinds of memories (short-term and long-term). This book gives much focus on the relationship of sleep and memory and how they preserve personality and all its characteristics. The study of the interrelation of the two bodily processes also aims to help clarify neurological bases of disorders of sleep and memory and other forms of mental illness. This text consists of 23 chapters that encompass a wide span of topics regarding sleep and memory. Some of these topics include blood-brain barrier; protein synthesis in RNA and central nervous system; neuronal activity patterns during REM sleep; post-trial reticular stimulation; and sleep-related hormones. This book also discusses the phylogenetic correlations of sleep and memory not just in mammals but also in reptiles, amphibians, fishes, and birds. This reference material is a valuable source of information to both students and professionals studying biology, psychology, pharmacology, and neuroscience.

Serotonin and Sleep: Molecular, Functional and Clinical Aspects
Serotonin and Sleep: Molecular, Functional and Clinical Aspects

Author: Jaime M. Monti

Publisher: Springer Science & Business Media

Published: 2008-03-04

Total Pages: 627

ISBN-13: 3764385618

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This book focuses on the neuropsychopharmacology of serotonin and its role in sleep and wakefulness, presenting neurochemical, electrophysiological, and neuropharmacological approaches to understand the mechanisms of serotonin and related substances. Covering core and contemporary topics in the area, this volume is valuable for all researchers interested in interdisciplinary studies concerning drugs affecting the central nervous system.

Drug Treatment of Sleep Disorders
Drug Treatment of Sleep Disorders

Author: Antonio Guglietta

Publisher: Springer

Published: 2014-11-28

Total Pages: 291

ISBN-13: 3319115146

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Following reviews on sleep physiology, regulation, pharmacology, and the neuronal networks regulating sleep and awakening, as well as a classification of sleep disorders, this book presents a number of major breakthroughs in the treatment of those disorders. These include recently approved drugs for treating insomnia, such as Doxepin; variations on previously approved molecules, e.g. Zolpidem sublingual preparation; or new chemical entities in advanced stages of clinical development, e.g. Orexin antagonists. Further topics discussed include drugs acting on the GABA receptor, such as Lorediplon and Eszopiclone; the treatment of excessive daytime drowsiness with cell therapy and drugs such as Modafinil, Armodafinil and Sodium oxybate; and the use of Tasimelteon in the treatment of circadian sleep disorders.

Dopamine and Sleep
Dopamine and Sleep

Author: Jaime M. Monti

Publisher: Springer

Published: 2016-10-24

Total Pages: 292

ISBN-13: 331946437X

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This book offers a comprehensive but highly readable compilation of papers on the role of dopamine in sleep and sleep disorders. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from established theories to the latest research advances. Accordingly, it represents an interdisciplinary, cutting-edge guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, pulmonologists, psychologists, and behavioral sleep medicine specialists.