Selenium and Selenoproteins in Brain Development, Function, and Disease
Author: Matthew William Pitts
Publisher: Frontiers Media SA
Published: 2022-02-18
Total Pages: 120
ISBN-13: 288974437X
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Trace Elements and Minerals in Health and Longevity
Author: Marco Malavolta
Publisher: Springer
Published: 2018-11-13
Total Pages: 332
ISBN-13: 3030037428
DOWNLOAD EBOOKThis book describes the role of trace elements in health and longevity, pursuing a biogerontological approach. It offers essential information on the impact of trace elements on molecular and physiological processes of aging, and on their impact on health in connection with aging. The major topics covered in its 11 chapters, each dedicated to a specific trace element or mineral, are: a) Role of the element in species longevity, b) Recommended intake for longevity in animal species and in the elderly, c) Deficiency and age-related disease, d) Excess/toxicity and age-related disease, and e) Interactions with drugs prescribed in the elderly. Clinical, animal and other laboratory models of interest in aging are included, which enable a more in-depth analysis to be made. The respective chapters are a mixture of overviews and more in-depth reviews in which the mechanisms of aging are described from the point of view of their specific interactions with trace elements and minerals.
Antioxidant Nutrients and Immune Functions
Author: Adrianne Bendich
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 173
ISBN-13: 1461305535
DOWNLOAD EBOOKThe detenmnation of optimal nutritional status has traditionally been based upon generalized parameters such as weight gain and body fat levels. Vitamin and mineral requirements were often related to the intakes needed to prevent overt signs of deficiency diseases such as beriberi or scurvy. However, in the past decade or so, there have been intensive investigations to determine the subtle changes in physiological functions associated with marginal micronutrient intakes. There is a growing consensus that immune system activities are very sensitive indicators of micronutrient status. During this decade, there has also been a rapid expansion of research in the role of free radicals and antioxidants in the major chronic diseases which afflict mankind( i.e. cancer, cardiovascular disease,and autoimmune disease). The main function of antioxidant nutrients in an appropriate diet is the prevention of oxidative damage to cells and their physiological functions. Antioxidant nutrients counteract free radicals and damaging oxidative actions on cell membranes. Since the cells of the immune system are rapidly differentiating and proliferating, such dividing and transforming cells are particularly susceptible to damage by oxidation. The interactions of antioxidant nutrition and immune system activities and disease resistance are therefore logical areas for research. Thus, the objective of this symposium was to bring together the leading investigators who have examined the immunological effects of dietary essential nutrients which share the capacity to act as antioxidants.
Protein Sensors and Reactive Oxygen Species
Author: Helmut Sies
Publisher: Academic Press
Published: 2002
Total Pages: 550
ISBN-13: 0121822486
DOWNLOAD EBOOKThis volume of Methods in Enzymology is concerned with the rapidly developing field of selenoprotein synthesis and its related molecular genetics. Progressive information on the topics of proteins as redox sensors, selenoproteins, and the thioredoxin system is studied using methods such as bioinformatics, DNA chip technology, cell biology, molecular genetics, and enzymology. The information on novel selenoproteins identified from genomic sequence data, as well as current knowledge on glutathione peroxidases, selenoprotein P, iodothyronine deiodinases, and thioredoxin reductases, is presented in a method-based approach.
Selenium
Author: Dolph L. Hatfield
Publisher: Springer Science & Business Media
Published: 2001
Total Pages: 350
ISBN-13: 9780792373353
DOWNLOAD EBOOKAs discussed in this book, a large body of evidence indicates that selenium is a cancer chemopreventive agent. Further evidence points to a role of this element in reducing viral expression, in preventing heart disease, and other cardiovascular and muscle disorders, and in delaying the progression of AIDS in HIV infected patients. Selenium may also have a role in mammalian development, in male fertility, in immune function and in slowing the aging process. The mechanism by which selenium exerts its beneficial effects on health may be through selenium-containing proteins. Selenium is incorporated into protein as the amino acid selenocysteine. Selenocysteine utilizes a specific tRNA, a specific elongation factor, a specific set of signals, and the codeword, UGA, for its cotranslational insertion into protein. It is indeed the 21st naturally occurring amino acid to be incorporated into protein and marks the first and only expansion of the genetic code since the code was deciphered in the mid 1960s.
Selenium Contamination in Water
Author: Pooja Devi
Publisher: John Wiley & Sons
Published: 2021-05-12
Total Pages: 436
ISBN-13: 1119693543
DOWNLOAD EBOOKThe contamination of environment and water resources by Selenium (Se) and its oxyanions from various sources are emerging contaminants of significant health and environmental concern. The primary sources include agricultural drainage water, mine drainage, residues from fossil fuels, thermoelectric power plants, oil refineries, and metal ores. Various methods and technologies have been developed which focus on the treatment of selenium-containing waters and wastewater. High concentrations of selenium in water cause various adverse impact to human health, such as carcinogenic, genotoxic, and cytotoxic effects. But in the lower concentrations, it is a useful constituent of the biological system. The range between toxicity and deficiency of selenium is minimal (40 to 400 μg per day), due to its dual nature. Selenium Contamination in Water contains the latest status and information on selenium’s origin, its chemistry and its toxicity to humans. The book represents a comprehensive and advanced reference book for students, researchers, practitioners, and policymakers in working in the field of metalloids, in particular selenium. A special emphasis is given on its geological distribution, monitoring techniques, and remedial technologies. As such, the authors critically analyze the various techniques used for the monitoring and removal of selenium from water. Featuring chapters arranged according to the major themes of the latest research, with specific case-studies from industrial experiences of selenium detection and removal, Selenium Contamination in Water will be particularly valued by researchers, practitioners, and policymakers in working in the field of metalloids including selenium.
Selenium
Author: Victor R Preedy
Publisher: Royal Society of Chemistry
Published: 2015-08-10
Total Pages: 667
ISBN-13: 1782622217
DOWNLOAD EBOOKAlthough toxic in large doses, selenium is an essential trace mineral in the animal diet and in some plants. It has a role in making antioxidant enzymes and a particular role in the functioning of the thyroid gland. This volume examines the chemical activity of selenium and its functional health effects eg towards cancers, in the heart and brain. It also covers other areas such as functional food enrichment, whole body metabolism, and the effects of selenium deficiency on health. Part of The Food and Nutritional Components in Focus series, this edited volume pools knowledge across scientific disciplines in a way that increases its applicability to a wide range of audiences. Victor Preedy’s own distinguished career in nutritional science has made him a prolific author of research articles and books in this area, and this project fills a gap in providing comprehensive synopses of food substances. Chemists, analytical scientists, forensic scientists, food scientists, as well as course lecturers will all benefit from this interdisciplinary title written by international experts in this area.
Clinical and Genetic Aspects of Epilepsy
Author: Zaid Afawi
Publisher: BoD – Books on Demand
Published: 2011-09-15
Total Pages: 217
ISBN-13: 953307700X
DOWNLOAD EBOOKThis book on Epilepsy was conceived and produced as a source of information on wide range of issues in epilepsy. We hope that it will help health care providers in daily practices and increase their understanding on diagnosis and treatment of epilepsies. The book was designed as an update for neuroscientists who are interested in epilepsy, primary care physicians and students in health care professions.
Selenium in the Environment
Author: Frankenberger
Publisher: CRC Press
Published: 1994-06-10
Total Pages: 496
ISBN-13: 9780824789930
DOWNLOAD EBOOKDiscusses the biochemical and geological cycling of selenium (Se), its worldwide distribution, and the factors controlling its fate and transport within and between major environmental media, presenting a global assessment of selenium's complex environmental behaviour. The focus of this work is upon Se management and remediation strategies.
Selenium
Author: Irene Rosenfeld
Publisher: Academic Press
Published: 2013-10-22
Total Pages: 424
ISBN-13: 1483275906
DOWNLOAD EBOOKSelenium: Geobotany, Biochemistry, Toxicity, and Nutrition focuses on the properties, characteristics, reactions, applications, chemistry, and transformations of selenium. The book first offers information on the geological distribution of selenium, including the formation of seleniferous soils, chemical forms of selenium in soils, selenium in water, selenium on the sea floor and in sea water, and geobotany. The text then takes a look at selenium indicator in plants and accumulation of selenium by plants. Discussions focus on selenium accumulations in indicator plants; selenium accumulation in farm crops and native grasses; factors that influence selenium accumulation in plants; and identification of indicators by germination tests. The manuscript elaborates on selenium poisoning in animals and prevention and control of selenium poisoning. Acute selenium poisoning, chronic selenium poisoning by inorganic selenium, and recognition of poisonous range plants are also discussed. The text also examines selenium in nutrition and the chemistry of selenium. The publication is a valuable source of data for readers interested in the study of selenium.
