A Clinician's Pearls & Myths in Rheumatology

A Clinician's Pearls & Myths in Rheumatology

Author: John H. Stone

Publisher: Springer Science & Business Media

Published: 2009-10-03

Total Pages: 489

ISBN-13: 1848009348

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Important strides have been made in understanding the pathophysiologic basis of many inflammatory conditions in recent years, but rheumatology remains a discipline in which diagnosis is rooted in the medical history skillfully extracted from the patient, the careful physical examination, and the discriminating use of laboratory tests and imaging. Moreover, selection of the most appropriate therapy for patients with rheumatic diseases also remains heavily reliant upon clinical experience. Medical disciplines such as rheumatology that depend significantly upon clinical wisdom are prone to the development of systems of ‘Pearls’ and ‘Myths,’ related to the diseases they call their own, a ‘Pearl’ being a nugget of truth about the diagnosis or treatment of a particular disease that has been gained by dint of clinical experience and a ‘Myth’ being a commonly held belief that influences the practice of many clinicians – but is false. This book will pool together the clinical wisdom of seasoned, expert rheumatologists who participate in the care of patients with autoimmune diseases, systemic inflammatory disorders, and all other rheumatic conditions.


The Heart in Rheumatic, Autoimmune and Inflammatory Diseases

The Heart in Rheumatic, Autoimmune and Inflammatory Diseases

Author: Udi Nussinovitch

Publisher: Academic Press

Published: 2017-02-10

Total Pages: 768

ISBN-13: 0128032685

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The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. - A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. - Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. - Presents an up-to-date "level of evidence and "strengths of recommendations for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.


Early Rheumatoid Arthritis

Early Rheumatoid Arthritis

Author: Paul Emery

Publisher:

Published: 2005

Total Pages: 0

ISBN-13: 9781416027676

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This issue covers the latest developments in the understanding of rheumatoid arthritis at the early stage. Treatments such as with newer biologic agents and conventional disease-modifying antirheumatic drugs are reviewed. Also included are articles on imaging modalities as a means of identifying those in the early stages and monitoring response to treatment.


Pulmonary Manifestations of Rheumatic Disease

Pulmonary Manifestations of Rheumatic Disease

Author: Paul F. Dellaripa

Publisher: Springer

Published: 2014-05-23

Total Pages: 227

ISBN-13: 1493907700

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The spectrum of systemic rheumatologic disease (often termed connective tissue disease) is characterized by autoimmune-mediated organ dysfunction, and the lungs are a frequent target. There are numerous pulmonary manifestations associated with connective tissue diseases, and all patients with rheumatologic disease are at risk of developing associated lung disease. Pulmonary Manifestations of Rheumatic Disease covers the comprehensive management of rheumatologic lung disease, which requires a multi-disciplinary approach and is optimized by active engagement by rheumatologists working closely with pulmonologists and other specialists. The book offers a practical reference using a case-based approach for practicing clinicians in the ongoing assessment and understanding of rheumatologic lung disease, and presents the science and pathophysiology underlying rheumatologic lung diseases. The first text of its kind specifically dedicated to describe diverse, commonplace, and challenging aspects of rheumatologic lung diseases, Pulmonary Manifestations of Rheumatic Disease serves as an invaluable tool for the practicing clinician.


Rheumatoid Arthritis Unmasked

Rheumatoid Arthritis Unmasked

Author: Kelly O'Neill Young

Publisher: Ra Patient Insights, LLC

Published: 2017-10-31

Total Pages: 280

ISBN-13: 9780998937472

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What if no one confused rheumatoid disease with just arthritis?What if the world understood that people with rheumatoid disease (RD) are not hypochondriacs because they have so many health problems?What if all of the effects of the disease were treated ¿ not dismissed or ignored?Rheumatoid Arthritis Unmasked solves a primary problem for people living with rheumatoid arthritis (RA), the false impression that they are only fighting a type of arthritis.The facts in this book shatter the myth that too often confuses family, friends, employers, and most importantly medical personnel. In Rheumatoid Arthritis Unmasked you¿ll learn why the historical term rheumatoid disease (RD) describes not a type of arthritis, but a complex systemic disease with arthritis as only one of its symptoms. You¿ll understand how the fallacy of ¿arthritis¿ not only creates communication problems for people fighting RD, but also contributes to the devastating mortality gap by hindering needed clinical care and research that will lead to a cure. Rheumatoid Arthritis Unmasked exposes the true nature of RD revealed in medical research. For about a decade, Kelly O¿Neill Young has studied current and past academic research about RA, reading hundreds of journal articles for this book alone. But Kelly, widely known as the RA Warrior, has also gained a unique perspective by listening to the millions of people who visit her website and social network.¿Patients will learn key dangers to fight to avoid becoming a victim of the RD mortality gap.¿Clinicians will become better at diagnosing and treating RD.¿Friends and family will understand that their loved one with RD has a serious disease.¿Researchers will be more able to conduct impactful and successful investigations of RD.¿Health policy makers and medical payers will be able to properly categorize extra-articular RD.Rheumatoid Arthritis Unmasked is more than a gripping account of the dangers of RD - it is a path for change. This book equips all RA warriors to guide their own medical care and safeguard their health. This book will arm you with facts that will save lives.


Skills in Rheumatology

Skills in Rheumatology

Author: Hani Almoallim

Publisher: Springer Nature

Published: 2021-01-05

Total Pages: 562

ISBN-13: 9811583234

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This Open Access book presents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance ofdetailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd). Featuring easy-to-understand flow diagrams and explaining the common medical problems associated with rheumatic disease, such as shortness of breath and anemia, it is not only a valuable resource to rheumatologists, but will also appeal to medical students, junior residents, and primary healthcare physicians.


Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders

Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders

Author: Lucia Morbidelli

Publisher: Academic Press

Published: 2019-02-09

Total Pages: 374

ISBN-13: 0128172797

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Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre-clinical and clinical activities on the role of nitric oxide donors/inhibitors used alone and in combination with other therapeutic agents for the treatment of a variety of diseases. This book examines various studies related to the application of novel therapeutic NO (donors/inhibitors) compounds in the treatment of various cancers. These studies have been shown to exert significant therapeutic activities against various cancers and various inflammatory diseases such as rheumatoid arthritis, Crohn's disease, allergies, and asthma, where no current effective therapies exist. Pathologies based on functional and structural vascular alterations are also taken into consideration. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students. - Provides readers with a clear overview of the recent findings and references as well as summaries, significant molecular pathways, and conclusions - Discusses new ideas proposed and makes suggestions for further investigations that will advance the field - Presents introductory and summary information on the contributions of the field, all the findings of the studies discussed, and projects future goals for research


Anti-Inflammatory Foods for Health

Anti-Inflammatory Foods for Health

Author: Barbara Rowe

Publisher: Fair Winds Press

Published: 2008-01-01

Total Pages: 193

ISBN-13: 1616734280

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Great food for inflammation sufferers. Cut your finger accidentally and the area will swell, redden, and heat up. This type of acute inflammatory response is the body's reaction to trauma, and it's an essential part of the healing process. But inflammation can be harmful when it hangs around too long and refuses to leave. When the inflammation switch refuses to turn off, the body operates as if it is always under attack (the older we get, the more likely this is to happen). White blood cells flood the system for weeks, months, and even years. Researchers are now linking low-grade, persistent inflammation to premature aging, heart disease, M.S., diabetes, Alzheimer's, psoriasis, arthritis, and cancer. While anti-inflammatory drugs do exist, they can injure the stomach or suppress the immune system. Fortunately, the situation can be remedied by a change in diet, specifically by altering the kinds of fats you eat. Omega-3 fatty acids tend to decrease inflammation while omega-6 fats and trans-fats increase inflammation. While many foods in the standard American diet (unrefined white flour, sugar, red meat, diary, fast food, and food additives) exacerbate inflammation, a healthy diet made up of fish, nuts, seeds, oils, lean grass-fed meats, and fruits and vegetables can help lessen or prevent inflammation. Likewise, certain spices such as turmeric, cloves, and ginger have proven anti-inflammatory activity. Anti-Inflammatory Foods for Health will help those with inflammation incorporate anti-inflammatory foods into their everyday diet. Sample recipes may include French-Canadian Pea Soup, Sumac Salmon, Maple-Ginger Butternut Squash, Lime-Ginger Glazed Chicken with Fennel Relish, Green Salad with Grapes and Sunflower Seeds, Cod with Saffron Sauce, and more.


Comorbidity in Rheumatic Diseases

Comorbidity in Rheumatic Diseases

Author: Yasser El Miedany

Publisher: Springer

Published: 2017-08-24

Total Pages: 439

ISBN-13: 3319599631

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This book explores comorbidity in patients with rheumatic diseases and details both care and treatment options in standard clinical practice. Patients with rheumatic diseases are clinically complex, and the interplay of their disease activity with associated conditions may lead to increased morbidity and mortality. Recently there have been major advances in the management of rheumatic diseases, however, without addressing the potential comorbid conditions, including cardiovascular disease; pulmonary disease; and depression; outcomes remain poor. ​​​ With its 19 chapters, covering the management of major rheumatic diseases (e.g. rheumatoid arthritis, systemic lupus erythematosus , and osteoarthritis), potential comorbidities and treatment recommendations, as well as possible interactions between conditions; this book addresses the gap between textbook medicine and day to day patients' care. Authors also discuss the new hot issue of the comorbidity index, comparing the standard tools to the recently developed indices and how they can assist the rheumatologists in determining disease burden, prognosis, and comorbidity probability. This book is an ideal clinical guide and reference that enables rheumatologists, internal medicine physicians, and residents to address the full clinical expression of these rheumatic diseases with views towards prevention or early management of comorbid conditions.


Rheumatoid Arthritis

Rheumatoid Arthritis

Author: John J. Cush

Publisher:

Published: 2008-01-01

Total Pages: 368

ISBN-13: 1932610286

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Emphasizes the importance of early intervention in RA with focus on pharmacologic treatment of RA. Detailed information on the various medications employed in treatment, including corticosteroids, NSAIDs DMARDs, biologic agents, and combination therapy is reviewed, including evidence based data on efficacy, safety, side effects, and monitoring requirements. Clinical evaluation is presented, including lab findings, joint scoring, diagnostic criteria, and radiographic outcomes. Surgical options and the management of advanced RA are disussed.