Concepts in Biochemical Pharmacology

Concepts in Biochemical Pharmacology

Author: Bernard B. Brodie

Publisher: Springer Science & Business Media

Published: 2013-11-27

Total Pages: 797

ISBN-13: 3642651771

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This volume of the Handbook of Experimental Pharmacology (Concepts in Biochemical Pharmacology) will show that pharma cology has finally arrived as a true discipline in its own right, and is no longer the handmaiden of organic chemistry and physiology. Instead it is an amalgam of all the biological sciences including biochemistry, biophysical chemistry, physiology, pathology and clinical medicine. In the volumes that make up Concepts in Bio chemical Pharmacology we hope to convince Medical Schools what should now be obvious, that pharmacology is no longer that dull topic bridging the basic sciences with medicine, but is probably the most important subject in the medical curriculum. We are grateful for the advice of Dr. Byron Clark, Director of the Pharmacology-Toxicology Program at the National Institutes of Health whose support made possible much of the work described in this volume. Contents Section Four: Methods 01 Stooging the MetoholiBm 01 Drugs Subsection A. Assay 01 Drugs and Their M etoholites Chapter 22 : Basic Principles in Development of Methods for Drug Assay. B. B. BRODIE. With 2 Figures 1 1 A. Introduction . . . . . . . . . . B. Principles of Developing a Method. . . . . . 1 I. Section of Method of Assay . . . . . . 1 II. Choice of Solvent for Extraction of Drug 2 III. Adsorption of Drugs by Glass Surfaces . . . . . . . . . . . . . . 3 IV. Recoveries of Known Amounts of Compound from Biological Material. 4 V. Assessment of Sensitivity 5 VI. Assessment of Specificity 5 References. . . . . . . . . . .


The Psychobiology of Mind

The Psychobiology of Mind

Author: William R. Uttal

Publisher: Psychology Press

Published: 2014-06-27

Total Pages: 810

ISBN-13: 1317668987

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Originally published in 1978, this book develops a conceptual synthesis of the field of physiological psychology, the science specifically concerned with the relationship between the brain and the mind. It was designed to elucidate the important questions under investigation, the basic intellectual and technical problems that were encountered, and the significance of the major empirical results of the time. Of equal or even greater importance is the author’s derivation of the general principles relating brain and mind that had emerged after decades of modern research into this important question. Included in the volume are historical and philosophical perspectives on the mind-brain problem as well as extensive discussions of instruments, methodology, empirical findings and theory. Here is a powerful heuristic tool that informs the reader about the concepts and ideas implicit in this science rather than simply exhaustively listing experimental results. The author does not ignore findings; he organizes them into three broad categories – localization; representation, and learning – then emphasizes the relationships among experiments. This is a book that synthesizes, integrates, and stresses concepts, principles and problems. The careful organization of the book makes it especially useful for students of brain and mind at all levels.


Reviews of Physiology, Biochemistry and Pharmacology 153

Reviews of Physiology, Biochemistry and Pharmacology 153

Author:

Publisher: Springer Science & Business Media

Published: 2005-02-18

Total Pages: 124

ISBN-13: 9783540240129

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Offers individual discussions of cell functions as they relate to physiology, biochemistry, or pharmacology. Topics covered include molecular mechanisms in membrane polarity, pharmacological properties of cerium compounds, and recruitment of Hsp70 chaperones.


Reviews of Physiology, Biochemistry and Pharmacology 158

Reviews of Physiology, Biochemistry and Pharmacology 158

Author: S.G. Amara

Publisher: Springer Science & Business Media

Published: 2007-05-17

Total Pages: 164

ISBN-13: 3540717919

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Contents E.I. Christensen and R. Nielsen: Role of Megalin and Cubilin in Renal Physiology and Pathophysiology G. Zifarelli and M. Pusch: CLC Chloride Channels and Transporters: A Biophysical and Physiological Perspective S.F.J. van de Graaf, R.J.M. Bindels and J.G.J. Hoenderop: Physiology of Epithelial Ca2 and Mg2+ Transport


Cellular Neurophysiology and Integration

Cellular Neurophysiology and Integration

Author: W. R. Uttal

Publisher: Psychology Press

Published: 2014-01-14

Total Pages: 391

ISBN-13: 1317768701

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First published in 1975. Because of its general importance to a number of related disciplines, students of the modern science of neurophysiology have benefited from time to time from an introductory survey presented at a more elementary level than is usually found in advanced textbooks. The dynamism of the field is such, however, that more up-to-date statements incorporating many of the exciting new findings concerning cellular neurophysiology are required periodically. This text is aimed at filling that need. It is an outgrowth of a part of a course on the neurophysiology of sensory processes taught by the author at The University of Michigan during the last ten years. This book is an attempt to present the subject matter at a level appropriate for advanced undergraduate students and first year graduate students whose knowledge of chemistry, physics, and mathematics is limited to introductory courses.


The Uttal Tetralogy of Cognitive Neuroscience

The Uttal Tetralogy of Cognitive Neuroscience

Author: William R. Uttal

Publisher: Psychology Press

Published: 2022-07-30

Total Pages: 2995

ISBN-13: 1317669045

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These four volumes, originally published between 1973 and 1988, were intended to provide a broad survey of cognitive neuroscience, a field known variously as physiological psychology or psychobiology in the 1970s and 1980s when the books were written. The general goal was to summarize what was known about the relation between brain and mind at that time, with an emphasis on sensory and perceptual topics. Out of print for many years, the Tetralogy is now available again, as a set for the first time (which is as the author envisaged it), or as individual volumes.