Medications for Opioid Use Disorder Save Lives
Medications for Opioid Use Disorder Save Lives

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2019-06-16

Total Pages: 175

ISBN-13: 0309486483

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The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Pain Management and the Opioid Epidemic
Pain Management and the Opioid Epidemic

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2017-09-28

Total Pages: 483

ISBN-13: 0309459575

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Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Task Force Report
Task Force Report

Author: United States. President's Commission on Law Enforcement and Administration of Justice

Publisher:

Published: 1967

Total Pages: 564

ISBN-13:

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Pain Modulation
Pain Modulation

Author: Howard L. Fields

Publisher: Elsevier Publishing Company

Published: 1988-01-01

Total Pages: 454

ISBN-13: 9780444809841

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This volume represents edited material that was presented at a conference on brainstem modulation of spinal nociception held in Beaune, France during July, 1987. Pain Modulation, Volume 77 in the series Progress in Brain Research reviews, analyses and suggests new research strategies on several relevant topics including: the endogenous opioid peptides; sites of action of opiates; the role of biogenic animes and non-opioid peptides in analgesia; dorsal horn circuitry; behavioural factors in the activation of pain modulating networks and clinical studies of nociceptive modulation.

Task Force Report: Narcotics and Drug Abuse
Task Force Report: Narcotics and Drug Abuse

Author: United States. Task Force on Narcotics and Drug Abuse

Publisher:

Published: 1967

Total Pages: 172

ISBN-13:

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The President's Commission on Law Enforcement and Administration of Justice created an advisory committee on narcotic and drug abuse in 1963 to develop a program of action. The Commission's report looks at drugs and their regulation (opiates, cocaine, marijuana, stimulants, and hallucinogens), drug law enforcement, characteristics of drug users and abusers, and the need to strengthen law enforcement. Specifically, the Commission recommends that enforcement and related staff of the Bureau of Customs be materially increased, that enforcement staff of the Bureau of Narcotics also be increased, and that States adopt a model drug abuse control act similar to the Federal Drug Abuse Control Amendments of 1965. In addition, the Commission recommends that recordkeeping provisions of the 1965 amendments be changed to require that records be segregated or kept in a manner that enables them to be promptly identified and inspected. The Commission's report discusses penalties, treatment programs, civil commitment, medical practice and addiction, and education. Individual papers incorporated as appendixes focus on mind-altering drugs and dangerous behavior, legislation for dangerous drugs, drug addiction treatment, civil commitment of drug addicts, and sentencing for drug offenses.