Raney Nickel-Assisted Synthesis of Heterocycles
Raney Nickel-Assisted Synthesis of Heterocycles

Author: Navjeet Kaur

Publisher: Elsevier

Published: 2022-04-04

Total Pages: 232

ISBN-13: 0323994938

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Raney Nickel-Assisted Synthesis of Heterocycles covers the synthesis of heterocycles using Raney nickel. The book focuses on the use of Raney-Ni, a common catalyst in hydrogenation reaction and its uses in the synthesis and preparation of heterocycles. Furthermore, it explains how the development of new approaches and strategic deployments in known approaches for the formation of complex heterocyclic compounds continue to drive the field of synthetic organic chemistry, along with updates on efforts to prepare heterocycles through the development of new and efficient synthetic transformations. Heterocyclic chemistry is an inexhaustible source of novel compounds, providing the most diverse chemical, physical and biological properties through the design of a wide range of combinations of carbon, hydrogen and heteroatoms. Significant focus has been paid to novel approaches to the formation of heterocyclic compounds, which are of practical use acting as modifiers and additives in a wide range of industries such as reprography, plastics, cosmetics, vulcanization accelerators, solvents, antioxidants and information storage. - Presents complete coverage of Raney Nickel assisted reactions - Includes the discovery, reactivities, advantages, disadvantages and other characteristics of Raney nickel - Presents new methodologies for the synthesis of heterocycles

Iodine-Assisted Synthesis of Six- and Seven-Membered Heterocycles
Iodine-Assisted Synthesis of Six- and Seven-Membered Heterocycles

Author: Navjeet Kaur

Publisher: Elsevier

Published: 2023-02-09

Total Pages: 382

ISBN-13: 0443152268

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Iodine-Assisted Synthesis of Six- and Seven-Membered Heterocycles covers both existing and the latest methods for the synthesis of various six- and seven-membered heterocycles using iodine. Covering an important and rapidly growing branch of heterocyclic chemistry, this book allows users easy access to the synthetic protocols for the synthesis of heterocycles, acting as a guide for how to make these important compounds employed as agrochemicals, pharmaceuticals, and veterinary products, using particular reagents. This book will be of interest to students, pharmacologists, biochemists, and organic and medicinal chemists. - Covers different methodologies for the synthesis of six- and seven-membered heterocycles using iodine - Includes the applications of six- and seven-membered heterocycles - Includes reactions schemes, mechanisms, and illustrations of the structure of reactive intermediates

3-Membered Heterocycle Synthesis
3-Membered Heterocycle Synthesis

Author: Navjeet Kaur

Publisher: Elsevier

Published: 2024-01-06

Total Pages: 328

ISBN-13: 0443135843

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3-membered heterocyclic rings offer an unusual combination of synthetic flexibility, reactivity, and atom economy. The main challenge for synthetic chemists, both in academia and industry, is the search for efficient approaches to target molecules. This book presents several methodologies for the synthesis of three-membered heterocyclic compounds and the readers will defiantly gain knowledge about the topic. With Three-Membered Heterocycle Synthesis, readers have detailed information about the synthesis of three-membered heterocyclic compounds. It comprehensively describes three-membered heterocyclic compounds synthesis, allowing the audience to quickly assess possible synthetic approaches. - Covers the applications of three-membered heterocycles - Includes comprehensive descriptions of heterocycle synthesis - Highlights methodologies for the synthesis of three-membered heterocycles - Analyzes several types and families of compounds, with a large set of recent examples in the field

Synthesis of 5-Membered Heterocycles
Synthesis of 5-Membered Heterocycles

Author: Navjeet Kaur

Publisher: Elsevier

Published: 2023-09-12

Total Pages: 442

ISBN-13: 0443134243

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Synthesis of Five-Membered Heterocycles: Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer helps readers quickly assess possible synthetic approaches. The book's audience, researchers, academic professionals and synthetic chemists both in industry and academia will find detailed information about the synthesis of five-membered heterocyclic compounds using dimethylformamide. Over the years, heterocyclic compounds, especially five-membered, have drawn more attention of pharmaceutical community because of their therapeutic value. The formation of heterocyclic compounds has turned out to be the keystone of synthetic organic chemistry. Dimethylformamide has played an important role in organic synthesis for a long time, and it is frequently utilized as a common solvent for chemical reactions and broadly used in industry as a reagent. It is a unique chemical and can play three other roles in organic chemistry, i.e., as stabilizer, reagent and catalyst. Due to its structure, DMF can participate in several reactions as a versatile building block for several units. - Includes comprehensive descriptions of heterocycle synthesis - Highlights many methods for the synthesis of five-membered heterocyclic compounds using dimethylformamide - Helps readers quickly assess possible synthetic approaches

Synthesis of 6- and 7-Membered Heterocycles
Synthesis of 6- and 7-Membered Heterocycles

Author: Navjeet Kaur

Publisher: Elsevier

Published: 2023-09-23

Total Pages: 352

ISBN-13: 0443161194

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Synthesis of Six- and Seven-Membered Heterocycles: The Role of DMF and its Synthesis compares different synthetic approaches using DMF, including the advantages and disadvantages of those reactions, green methods, and the sustainability of reported synthetic methodologies, especially the microwave methods. The book presents several methodologies for the synthesis of six- and seven-membered heterocyclic compounds using dimethylformamide. Users will find the most up-to-date information in this fast-moving field which can be particularly challenging. With DMF drawing the attention of synthetic organic chemists, this book will help readers understand further developments in the uses of dimethylformamide beyond just its use as a polar solvent. As it can be expected that the use of dimethylformamide as a precursor will continue to grow in organic synthesis with new applications in sustainable and green chemistry, this book provides an ideal primer on the topics covered. - Compares different methods, reagents, reaction conditions, advantages and disadvantages - Discusses and compares different methodologies with green techniques - Includes reaction schemes, reaction mechanisms and the structure of reactive intermediates

4-Membered Heterocycle Synthesis
4-Membered Heterocycle Synthesis

Author: Navjeet Kaur

Publisher: Elsevier

Published: 2023-07-26

Total Pages: 334

ISBN-13: 0443132607

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Four-Membered Heterocycle Synthesis offers a comprehensive approach to these unstable organic compounds, providing a systematic introduction to the synthesis and reactions of all common four-membered heterocycles and illustrating different methods to prepare specific four-membered heterocycles. Four-membered heterocyclic compounds are known as a class of unstable organic compounds because of their strain characteristics, which make them very beneficial as precursors for the formation of a broad range of complex heterocyclic molecules and for synthetic elaboration. - Provides a systematic introduction to the synthesis and reactions of all common four-membered heterocycles - Highlights different methods to prepare specific 4-membered heterocycles - Analyzes several types and families of compounds, with a large set of recent examples in the field

8-Membered Heterocycle Synthesis
8-Membered Heterocycle Synthesis

Author: Navjeet Kaur

Publisher: Elsevier

Published: 2023-02-21

Total Pages: 566

ISBN-13: 032395653X

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8-Membered Heterocycle Synthesis focuses on both the new and established methods for the synthesis of various 8-membered heterocycles. 8-membered heterocyclic compounds act as target molecules for a wide range of synthetic studies and are present in a broad range of natural products, showing a wide variety of pharmaceutical and biological properties. Covering an important and rapidly growing branch of heterocyclic chemistry, this book brings together every protocol for the synthesis of 8-membered heterocycles in one place, allowing the reader to see all the possibilities for making a particular compound using one particular reagent. Providing up-to-date and comprehensive information about the synthesis of medium-ring heterocycles and the latest information on this fast-moving field, with easy access to the synthetic protocols for different 8-membered heterocycles, case studies, and application, this book will be essential reading for students, pharmacologists, biochemists, organic and medicinal chemists, researchers, and academic professionals. - Covers the different methodologies for the synthesis of eight-membered heterocycles - Includes summary schemes for each type of heterocycle, giving an overview of all the reactants that can be used, and the experimental conditions - Includes discussion of the applications of eight-membered heterocycles

Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles
Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles

Author: Navjeet Kaur

Publisher: Elsevier

Published: 2020-04-25

Total Pages: 528

ISBN-13: 0128202831

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Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles provides a useful guide to key approaches being explored in this area. The volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Drawing on the experience of its expert author, the book is a useful guide on the key approaches being explored in this area. Following a user-friendly structure based on specific six-membered heterocycle ring groups, this volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. - Highlights new methodologies for the synthesis of different six-membered heterocycles - Provides an up-to-date overview of this fast-moving field with an easy-to-use structure - Includes novel approaches used in the study and application of catalysts in synthetic organic reactions

5-Membered Heterocycle Synthesis Using Iodine
5-Membered Heterocycle Synthesis Using Iodine

Author: Navjeet Kaur

Publisher: Elsevier

Published: 2023-01-24

Total Pages: 502

ISBN-13: 0443189420

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5-Membered Heterocycle Synthesis Using Iodine presents both old and new methods for the synthesis of various five-membered heterocycles using iodine, providing information for making specific compounds using particular reagents. Heterocyclic frameworks represent the main structural subunits of many biologically active compounds and natural products, and the ability of heterocycles to act both as reactive pharmacophores and biomimetics has greatly contributed to their unique value as traditional key elements of various drugs. Contemporary developments in process chemistry and discovery emphasize novel sustainable synthetic pathways as fast and ecologically acceptable alternatives to the traditional protocols. This book serves as a guide for students, pharmacologists, biochemists, organic and medicinal chemists, researchers, and academic professionals to obtain easy access to synthetic protocols for different five-membered heterocycles using iodine. - Covers the applications of five-membered heterocycles - Highlights methodologies for the synthesis of five-membered heterocycles using iodine - Contains the most up-to-date information in this fast-moving field

Synthesis of Aziridines and Oxaziridines from Imines
Synthesis of Aziridines and Oxaziridines from Imines

Author: Navjeet Kaur

Publisher: Elsevier

Published: 2024-01-13

Total Pages: 354

ISBN-13: 0443220603

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The smallest possible saturated azaheterocycle, aziridine, is well-known to organic chemists for its tremendous potential in pharmaceutical chemistry and organic synthesis. The general biological importance of aziridines is proven by the fact that they found several uses as subunits in pharmacologically active compounds such as antitumor agents, enzyme inhibitors, and antibiotics. Although aziridines are highly reactive, this framework occurs in many synthetic compounds and the natural products of biological interest also contain aziridine skeleton in their structures. The synthetic community is captivated with prospects of selective synthesis and conversions of aziridines. Several important advances in this area have been witnessed in recent years and discovering efficient novel methods for the synthesis of aziridines has been very active field of research. Its powerful synthetic utility has been described by an overpowering amount of documentation on the approaches for the formation of aziridine. Synthesis of Aziridines and Oxaziridines from Imines describes the new and old methods for the synthesis of aziridines from imines and covers an important and rapidly growing branch of heterocyclic chemistry. Readers will have access to different methods and information allowing them to evaluate which method is most suitable for particular cases. - Focuses on the biological importance of different heterocycles - Describes traditional and innovative methods for the synthesis of aziridines from imines - Includes comparison amongst different methods, reagents, reaction conditions in tabulated forms, advantages, disadvantages, and critical analysis of different methodologies with respect to their comparison with green technique