Radiotherapy in Prostate Cancer

Radiotherapy in Prostate Cancer

Author: Hans Geinitz

Publisher: Springer

Published: 2014-11-18

Total Pages: 288

ISBN-13: 3642370993

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Today, the arsenal of “high-precision” or “targeted” radiotherapy includes a variety of techniques and approaches that, like the pieces of a puzzle, need to be put together to provide the prostate cancer patient with high-level optimized radiation treatment. This book examines in detail the role of these innovative radiation techniques in the management of prostate cancer. In addition, a variety of current controversies regarding treatment are carefully explored, including whether prophylactic treatment of the pelvic lymphatics is essential, the magnitude of the effect of dose escalation, whether a benefit accrues from hypofractionation, and what evidence exists for the superiority of protons or heavy ions. Radiotherapy in Prostate Cancer: Innovative Techniques and Current Controversies is intended for both radiation oncologists and urologists with an interest in the up-to-date capabilities of modern radiation oncology for the treatment of prostate cancer.


Controversies and Perspectives in the Use of Postoperative Radiotherapy for Prostate Cancer

Controversies and Perspectives in the Use of Postoperative Radiotherapy for Prostate Cancer

Author: Alan Dal Pra

Publisher: Frontiers Media SA

Published: 2018-03-23

Total Pages: 74

ISBN-13: 2889454509

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The use of radical prostatectomy in patients with high risk of recurrence has significantly increased during the past 10 years. Thus, adjuvant radiation as a part of multimodality treatment or salvage radiation at the evidence of prostate-specific antigen (PSA) progression represents mainstay curative-intent options for a great number of prostate cancer patients. Although, few randomized trials and many retrospective studies have been published, many uncertainties still mold the discussions on the best treatment management for men after prostatectomy. This research topic successfully intended to foster discussions on current controversies in the use of postoperative radiotherapy and to present novel perspectives for treatment optimization.


Stereotactic Radiosurgery for Prostate Cancer

Stereotactic Radiosurgery for Prostate Cancer

Author: Michael J. Zelefsky

Publisher: Springer

Published: 2018-09-28

Total Pages: 217

ISBN-13: 3319924532

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This book offers a comprehensive evaluation of the use of stereotactic body radiosurgery (SBRT) for the treatment of prostate cancer. The rationale, selection criteria, and treatment planning for prostate SBRT are explained. Important imaging and anatomic considerations are discussed, and detailed consideration devoted to organ motion and tumor tracking during SBRT. Outcomes of therapy are then examined, with thorough appraisal of side effect profiles and quality of life impacts. Clear guidance is provided on how to deliver the therapy in a way that minimizes the risk of long-term urinary and rectal toxicities. Stereotactic radiosurgery for prostate cancer is an increasingly used form of treatment. Retrospective investigations have demonstrated the safe application of high-dose treatments, with 5-year results comparable to those achieved with protracted external beam radiotherapy. Prospective studies are underway comparing SBRT with more traditional forms of image-guided and intensity-modulated radiotherapy. In offering in-depth guidance on safe delivery of prostate SBRT, this book will be of value for students of radiation oncology, more experienced practitioners, and medical physicists.


Image-Guided IMRT

Image-Guided IMRT

Author: Thomas Bortfeld

Publisher: Springer Science & Business Media

Published: 2006-05-28

Total Pages: 452

ISBN-13: 3540303561

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Intensity-modulated radiation therapy (IMRT), one of the most important developments in radiation oncology in the past 25 years, involves technology to deliver radiation to tumors in the right location, quantity and time. Unavoidable irradiation of surrounding normal tissues is distributed so as to preserve their function. The achievements and future directions in the field are grouped in the three sections of the book, each suitable for supporting a teaching course. Part 1 contains topical reviews of the basic principles of IMRT, part 2 describes advanced techniques such as image-guided and biologically based approaches, and part 3 focuses on investigation of IMRT to improve outcome at various cancer sites.


Radiotherapy of Prostate Cancer

Radiotherapy of Prostate Cancer

Author: Carlo Greco

Publisher: CRC Press

Published: 2000-07-06

Total Pages: 500

ISBN-13: 9789057024825

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Radiotherapy of Prostate Cancer aims to guide the reader through the recent data from clinical trials, to highlight the various approaches and to clarify the role of traditional radiation therapy in the management of the disease. It details established management protocols as well as more controversial isssues and experimental approaches ranging from external beam radiotherapy, 3-dimensional conformal radiotherapy, heavy particle therapy and brachytherapy. The reader will not only gain a vast amount of knowledge regarding the many modes of currently available radiotherapy strategies for this disease, but will also gain a clearer perspective of the indications of a particular modality's use and how best to integrate therapy for the individual patient.


Chemotherapy and Immunotherapy in Urologic Oncology

Chemotherapy and Immunotherapy in Urologic Oncology

Author: Edouard J. Trabulsi

Publisher: Springer Nature

Published: 2020-09-29

Total Pages: 303

ISBN-13: 3030520218

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This book is designed to familiarize clinical practitioners in systemic therapy options and medical management of urologic malignancies including prostate cancer, bladder and upper tract urothelial carcinoma, and renal cell carcinoma. Organized by organ system, the text highlights new therapies such as novel forms of androgen deprivation, cytotoxic chemotherapy, immune check point and immunomodulatory agents, and targeted therapies. Written by experts in the field, the book also reviews current chemotherapy and immunotherapy regimens for genitourinary malignancies and discusses indications, outcomes, and toxicities, as well as clinical trial concepts. Each of the book’s chapters offers a bulleted box of clinical pearls on the particular role of the APP. Chemotherapy and Immunotherapy in Urologic Oncology: A Guide for the Advanced Practice Provider is a resource for urologists, uro-radiologists, medical clinicians and family practitioners alike, familiarizing its audiences with systemic therapy regimens for urologic malignancies, as well as their expected outcomes and side effects.


Prostate Cancer

Prostate Cancer

Author: Allen M. Chen, MD

Publisher: Demos Medical Publishing

Published: 2011-04-12

Total Pages: 172

ISBN-13: 1617050679

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This issue of Radiation Medicine Rounds examines the latest advances in the use of radiation medicine in treatment of prostate cancer Prostate cancer is the most common cancer in males and radiation therapy is a major tool in the management of the disease. This issue of Radiation Medicine Rounds includes reviews of all major recent advances in treatment of favorable, intermediate and high-risk prostate cancer as well as newer modalities such as brachytherapy, stereotactic body radiation therapy, and proton beam radiotherapy. Articles also review current knowledge in the areas of new biomarkers, risk stratification, and risk stratification. This issue of RMR will provide the practitioner with a full current overview of the present best practices and recent research in management of this complex and challenging disease. Radiation Medicine Rounds features: In-depth, up-to-date expert reviews and analysis of major new developments in all areas of Radiation Medicine Each issue edited by an authority in that subject area Each issue focused on a single major topic in Radiation Medicine, providing coverage of advances in radiation science, radiation medicine technology, radiation medicine practice, and assessment of recent quality and outcome studies


Target Volume Delineation and Treatment Planning for Particle Therapy

Target Volume Delineation and Treatment Planning for Particle Therapy

Author: Nancy Y. Lee

Publisher: Springer

Published: 2017-12-19

Total Pages: 393

ISBN-13: 3319424785

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This handbook is designed to enable radiation oncologists to treat patients appropriately and confidently by means of particle therapy. The orientation and purpose are entirely practical, in that the focus is on the physics essentials of delivery and treatment planning , illustration of the clinical target volume (CTV) and associated treatment planning for each major malignancy when using particle therapy, proton therapy in particular. Disease-specific chapters provide guidelines and concise knowledge on CTV selection and delineation and identify aspects that require the exercise of caution during treatment planning. The treatment planning techniques unique to proton therapy for each disease site are clearly described, covering beam orientation, matching/patching field techniques, robustness planning, robustness plan evaluation, etc. The published data on the use of particle therapy for a given disease site are also concisely reported. In addition to fully meeting the needs of radiation oncologists, this "know why" and “know how” guide to particle therapy will be valuable for medical physicists, dosimetrists, and radiation therapists.


Stereotactic Body Radiation Therapy

Stereotactic Body Radiation Therapy

Author: Simon S. Lo

Publisher: Springer Science & Business Media

Published: 2012-08-28

Total Pages: 433

ISBN-13: 364225604X

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Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.