Quantitative Medical Data Analysis Using Mathematical Tools And Statistical Techniques
Quantitative Medical Data Analysis Using Mathematical Tools And Statistical Techniques

Author: Don Hong

Publisher: World Scientific

Published: 2007-07-10

Total Pages: 364

ISBN-13: 9814476234

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Quantitative biomedical data analysis is a fast-growing interdisciplinary area of applied and computational mathematics, statistics, computer science, and biomedical science, leading to new fields such as bioinformatics, biomathematics, and biostatistics. In addition to traditional statistical techniques and mathematical models using differential equations, new developments with a very broad spectrum of applications, such as wavelets, spline functions, curve and surface subdivisions, sampling, and learning theory, have found their mathematical home in biomedical data analysis.This book gives a new and integrated introduction to quantitative medical data analysis from the viewpoint of biomathematicians, biostatisticians, and bioinformaticians. It offers a definitive resource to bridge the disciplines of mathematics, statistics, and biomedical sciences. Topics include mathematical models for cancer invasion and clinical sciences, data mining techniques and subset selection in data analysis, survival data analysis and survival models for cancer patients, statistical analysis and neural network techniques for genomic and proteomic data analysis, wavelet and spline applications for mass spectrometry data preprocessing and statistical computing.

Medical Uses of Statistics
Medical Uses of Statistics

Author: John C. Bailar III

Publisher: CRC Press

Published: 2019-05-20

Total Pages: 490

ISBN-13: 0429529600

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This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results.

Handbook of Cancer Models with Applications
Handbook of Cancer Models with Applications

Author: W. Y. Tan

Publisher: World Scientific

Published: 2008

Total Pages: 592

ISBN-13: 9812779477

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Composed of contributions from an international team of leading researchers, this book pulls together the most recent research results in the field of cancer modeling to provide readers with the most advanced mathematical models of cancer and their applications.Topics included in the book cover oncogenetic trees, stochastic multistage models of carcinogenesis, effects of ionizing radiation on cell cycle and genomic instability, induction of DNA damage by ionizing radiation and its repair, epigenetic cancer models, bystander effects of radiation, multiple pathway models of human colon cancer, and stochastic models of metastasis. The book also provides some important applications of cancer models to the assessment of cancer risk associated with various hazardous environmental agents, to cancer screening by MRI, and to drug resistance in cancer chemotherapy. An updated statistical design and analysis of xenograft experiments as well as a statistical analysis of cancer occult clinical data are also provided.The book will serve as a useful source of reference for researchers in biomathematics, biostatistics and bioinformatics; for clinical investigators and medical doctors employing quantitative methods to develop procedures for cancer diagnosis, prevention, control and treatment; and for graduate students.

Statistical Methods in Medical Research
Statistical Methods in Medical Research

Author: Peter Armitage

Publisher: John Wiley & Sons

Published: 2013-07-01

Total Pages: 664

ISBN-13: 1118702581

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The explanation and implementation of statistical methods for the medical researcher or statistician remains an integral part of modern medical research. This book explains the use of experimental and analytical biostatistics systems. Its accessible style allows it to be used by the non-mathematician as a fundamental component of successful research. Since the third edition, there have been many developments in statistical techniques. The fourth edition provides the medical statistician with an accessible guide to these techniques and to reflect the extent of their usage in medical research. The new edition takes a much more comprehensive approach to its subject. There has been a radical reorganization of the text to improve the continuity and cohesion of the presentation and to extend the scope by covering many new ideas now being introduced into the analysis of medical research data. The authors have tried to maintain the modest level of mathematical exposition that characterized the earlier editions, essentially confining the mathematics to the statement of algebraic formulae rather than pursuing mathematical proofs. Received the Highly Commended Certificate in the Public Health Category of the 2002 BMA Books Competition.

Statistical Methods in Healthcare
Statistical Methods in Healthcare

Author: Frederick W. Faltin

Publisher: John Wiley & Sons

Published: 2012-07-24

Total Pages: 533

ISBN-13: 1119942047

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Statistical Methods in Healthcare In recent years the number of innovative medicinal products and devices submitted and approved by regulatory bodies has declined dramatically. The medical product development process is no longer able to keep pace with increasing technologies, science and innovations and the goal is to develop new scientific and technical tools and to make product development processes more efficient and effective. Statistical Methods in Healthcare focuses on the application of statistical methodologies to evaluate promising alternatives and to optimize the performance and demonstrate the effectiveness of those that warrant pursuit is critical to success. Statistical methods used in planning, delivering and monitoring health care, as well as selected statistical aspects of the development and/or production of pharmaceuticals and medical devices are also addressed. With a focus on finding solutions to these challenges, this book: Provides a comprehensive, in-depth treatment of statistical methods in healthcare, along with a reference source for practitioners and specialists in health care and drug development. Offers a broad coverage of standards and established methods through leading edge techniques. Uses an integrated case study based approach, with focus on applications. Looks at the use of analytical and monitoring schemes to evaluate therapeutic performance. Features the application of modern quality management systems to clinical practice, and to pharmaceutical development and production processes. Addresses the use of modern statistical methods such as Adaptive Design, Seamless Design, Data Mining, Bayesian networks and Bootstrapping that can be applied to support the challenging new vision. Practitioners in healthcare-related professions, ranging from clinical trials to care delivery to medical device design, as well as statistical researchers in the field, will benefit from this book.

Converting Data into Evidence
Converting Data into Evidence

Author: Alfred DeMaris

Publisher: Springer Science & Business Media

Published: 2013-07-23

Total Pages: 231

ISBN-13: 1461477921

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Converting Data into Evidence: A Statistics Primer for the Medical Practitioner provides a thorough introduction to the key statistical techniques that medical practitioners encounter throughout their professional careers. These techniques play an important part in evidence-based medicine or EBM. Adherence to EBM requires medical practitioners to keep abreast of the results of medical research as reported in their general and specialty journals. At the heart of this research is the science of statistics. It is through statistical techniques that researchers are able to discern the patterns in the data that tell a clinical story worth reporting. The authors begin by discussing samples and populations, issues involved in causality and causal inference, and ways of describing data. They then proceed through the major inferential techniques of hypothesis testing and estimation, providing examples of univariate and bivariate tests. The coverage then moves to statistical modeling, including linear and logistic regression and survival analysis. In a final chapter, a user-friendly introduction to some newer, cutting-edge, regression techniques will be included, such as fixed-effects regression and growth-curve modeling. A unique feature of the work is the extensive presentation of statistical applications from recent medical literature. Over 30 different articles are explicated herein, taken from such journals. With the aid of this primer, the medical researcher will also find it easier to communicate with the statisticians on his or her research team. The book includes a glossary of statistical terms for easy access. This is an important reference work for the shelves of physicians, nurses, nurse practitioners, physician’s assistants, medical students, and residents.

Mathematics, Statistics, and Systems for Health
Mathematics, Statistics, and Systems for Health

Author: Norman T. J. Bailey

Publisher: John Wiley & Sons

Published: 1977

Total Pages: 242

ISBN-13:

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The purpose of this book is to make available to a wide reading public a greater understanding of the role of quantitative methods in helping to develop and improve medical care and health services throughout the world. Special attention has been paid to the significance and potentialities of mathematics, statistics, modelling, computers, operational research, systems analysis, and system dynamics. The edition adopts an intergrated treatment, and keeps the purely mathematical aspects down to a minimum. It is more concerned with general notions and principles than with technical mathematical details.

New Developments in Biostatistics and Bioinformatics
New Developments in Biostatistics and Bioinformatics

Author: Jianqing Fan

Publisher: World Scientific

Published: 2009

Total Pages: 295

ISBN-13: 9812837442

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This book presents an overview of recent developments in biostatistics and bioinformatics. Written by active researchers in these emerging areas, it is intended to give graduate students and new researchers an idea of where the frontiers of biostatistics and bioinformatics are as well as a forum to learn common techniques in use, so that they can advance the fields via developing new techniques and new results. Extensive references are provided so that researchers can follow the threads to learn more comprehensively what the literature is and to conduct their own research. In particulars, the book covers three important and rapidly advancing topics in biostatistics: analysis of survival and longitudinal data, statistical methods for epidemiology, and bioinformatics.

Essentials of Applied Quantitative Methods for Health Services
Essentials of Applied Quantitative Methods for Health Services

Author: James Lewis

Publisher: Jones & Bartlett Learning

Published: 2011

Total Pages: 333

ISBN-13: 076375871X

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Essentials of Applied Quantitative Methods for Health Services Management shows students how to use statistics in all aspects of health care administration. Offering careful, step-by-step instructions for calculations using Microsoft Excel, this hands-on resource begins with basic foundational competencies in statistics, and then walks the reader through forecasting, designing and analyzing systems, and project analysis. The text stresses the application of concepts, models, and techniques and provides problems involving all of the methods. It is intended to build a student management and planning tools repertoire. Ideal for junior and seniors in baccalaureate level health administration programs as well as first year graduate students in non-MBA health administration programs, this book requires limited previous knowledge of statistics; its mathematical dimension is equal to basic high school algebra.

Introduction to Statistical Analysis of Laboratory Data
Introduction to Statistical Analysis of Laboratory Data

Author: Alfred Bartolucci

Publisher: John Wiley & Sons

Published: 2015-12-02

Total Pages: 259

ISBN-13: 1118736869

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Introduction to Statistical Analysis of Laboratory Data presents a detailed discussion of important statistical concepts and methods of data presentation and analysis Provides detailed discussions on statistical applications including a comprehensive package of statistical tools that are specific to the laboratory experiment process Introduces terminology used in many applications such as the interpretation of assay design and validation as well as “fit for purpose” procedures including real world examples Includes a rigorous review of statistical quality control procedures in laboratory methodologies and influences on capabilities Presents methodologies used in the areas such as method comparison procedures, limit and bias detection, outlier analysis and detecting sources of variation Analysis of robustness and ruggedness including multivariate influences on response are introduced to account for controllable/uncontrollable laboratory conditions