Purinergic pharmacology, volume II
Author: Francisco Ciruela
Publisher: Frontiers Media SA
Published: 2023-06-07
Total Pages: 187
ISBN-13: 283252575X
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Pharmacology of Purine and Pyrimidine Receptors
Author:
Publisher: Academic Press
Published: 2011-07-13
Total Pages: 558
ISBN-13: 0123855330
DOWNLOAD EBOOKThis is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. - Authors are the leading authorities in their fields - Subject matter is important for understanding tissue protection - Subject matter is of intense interest for new drug development
General and Molecular Pharmacology
Author: Francesco Clementi
Publisher: John Wiley & Sons
Published: 2015-07-01
Total Pages: 784
ISBN-13: 1118768590
DOWNLOAD EBOOKWith a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students • Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs • Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties • Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development • Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, and all figures and tables from the book
Receptors P1 and P2 as Targets for Drug Therapy in Humans
Author: Robson Faria
Publisher: BoD – Books on Demand
Published: 2020-03-11
Total Pages: 112
ISBN-13: 1789845343
DOWNLOAD EBOOKThis book aims to provide a brief update on the functions of purinergic receptors in various systems, in addition to the signaling pathway activated to mediate these functions. We address the influence of hypoxia by modulating the activity of these receptors under physiological and pathophysiological conditions. Additionally, we describe the mechanisms of induction of pain and inflammation in different systems. Finally, the book discusses some of the main bioinformatics tools currently used to improve or discover new prototypes capable of selectively acting on these receptors with estimated parameters of satisfactory solubility and toxicity for possible commercial implementation.
Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters
Author: M. Morad
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 586
ISBN-13: 9401139903
DOWNLOAD EBOOKKnowledge of cardiac ion channels and transporters has advanced remarkably in the last two decades with the development of patch-clamp and molecular biological techniques. This textbook offers a comprehensive overview of structures and functions of ion channels and transporters in the heart. Readers are first introduced to the molecular biology and electrophysiology of all the important ion channels. After discussing their developmental changes, the pharmacology and pathophysiology of clinically-relevant ion channels are reviewed. Molecular aspects of the cardiac excitation-contraction coupling and intracellular Ca2+ regulation by ion transporters are also described. The book will be useful to electrophysiologists, cardiac physiologists and pharmacologists, and molecular biologists interested in ion channels at all levels. For research specialists, the book will provide a perspective of the field. The book can be used as a reference source for working scientists in the fields of ion channels, biophysics, cardiac electrophysiology, and pharmacology. It is aimed at graduate and medical students, designed for use as a textbook for graduate and medical courses.
Introduction to Neuropsychopharmacology
Author: Leslie Iversen
Publisher: Oxford University Press
Published: 2009
Total Pages: 568
ISBN-13: 0195380533
DOWNLOAD EBOOKThe text ranges from drugs that affect the mood and behavior to hypnotics, narcotics, anticonvulsants, and analgesics, as well as a variety of drugs that affect the autonomic nervous system and psychoactive drugs used for non-medical reasons - nicotine, alcohol, opiates, psychostimulants and cannabis."--BOOK JACKET.
Pharmacology - Volume II
Author: Harry Majewski
Publisher: EOLSS Publications
Published: 2009-10-29
Total Pages: 428
ISBN-13: 184826254X
DOWNLOAD EBOOKPharmacology is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. Pharmacology is the study of the actions of chemicals on the body and most usually it is defined as chemicals that can have a therapeutic action to treat disease. Since it looks at the interaction between chemicals and body systems pharmacology utilizes the basic disciplines of chemistry, biochemistry, physiology, pathology and microbiology in its practice. Pharmacology is a foundation science for pharmacy which is the rational prescribing of drugs to treat disease and the foundation science for toxicology which is the study of the toxic actions of chemicals on the body. The two volumes are organized in groups of chapters as follows: The first group of chapters discuss pharmacological principles and these include chapters on Pharmacodynamics; Pharmacokinetics, Neuropharmacology, Autonomic Pharmacology and Clinical Pharmacology. The second group of chapters discusses the processes of Drug discovery and the Safety requirements for drugs to be used therapeutically and include Drug Discovery and Safety Pharmacology assessment. The largest group of chapters discuss different therapeutic areas and include Cardiovascular and renal pharmacology; Endocrine pharmacology; Neuropsychopharmacology; Pulmonary Pharmacology; Gastrointestinal pharmacology; Poisons venoms and toxins; Drugs on skeletal muscle; the Pharmacotherapy of inflammation; Reproductive pharmacology; Pain pharmacology and analgesia. The final group of chapters discuss new approaches and include Pharmacogenetics and pharmacogenomics; Immunopharmacology and Gene therapy. These two volumes are aimed at the following a wide spectrum of audiences from the merely curious to those seeking in-depth knowledge: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs.
Purinergic Pharmacology
Author: Francisco Ciruela
Publisher: Frontiers Media SA
Published: 2019-08-16
Total Pages: 852
ISBN-13: 2889459470
DOWNLOAD EBOOKRang & Dale's Pharmacology
Author: James M. Ritter
Publisher: Elsevier Health Sciences
Published: 2018-11-04
Total Pages: 809
ISBN-13: 0702074462
DOWNLOAD EBOOKWorld-renowned coverage of today's pharmacology at your fingertips - Keeps you up-to-date with new information in this fast-changing field, including significantly revised coverage of CNS drugs, cognitive enhancers, anti-infectives, biologicals/biopharmaceuticals, lifestyle drugs, and more. - Includes access to unique features, including more than 100 brand new chapter-specific multiple-choice questions and 6 new cases for immediate self-assessment. - Features a color-coded layout for faster navigation and cross-referencing. - Clarifies complex concepts with Key Points boxes, Clinical Uses boxes and full-color illustrations throughout.
Pharmacology
Author: Luca Gallelli
Publisher: BoD – Books on Demand
Published: 2012-03-14
Total Pages: 735
ISBN-13: 9535102222
DOWNLOAD EBOOKThe history of pharmacology travels together to history of scientific method and the latest frontiers of pharmacology open a new world in the search of drugs. New technologies and continuing progress in the field of pharmacology has also changed radically the way of designing a new drug. In fact, modern drug discovery is based on deep knowledge of the disease and of both cellular and molecular mechanisms involved in its development. The purpose of this book was to give a new idea from the beginning of the pharmacology, starting from pharmacodynamic and reaching the new field of pharmacogenetic and ethnopharmacology.
