Principles of Evolutionary Medicine

Principles of Evolutionary Medicine

Author: Peter D. Gluckman

Publisher: Oxford University Press

Published: 2016

Total Pages: 401

ISBN-13: 0199663920

DOWNLOAD EBOOK

A new updated edition of the first integrated and comprehensive textbook to explain the principles of evolutionary biology from a medical perspective and to focus on how medicine and public health might utilise evolutionary biology.


Evolution and Medicine

Evolution and Medicine

Author: Robert Perlman

Publisher: OUP Oxford

Published: 2013-05-30

Total Pages: 177

ISBN-13: 0191637793

DOWNLOAD EBOOK

Evolution and Medicine provides an accessible introduction to the new field of evolutionary medicine. Evolutionary concepts help explain why we remain vulnerable to disease, how pathogens and cancer cells evolve, and how the diseases that affected our evolutionary ancestors have shaped our biology. The book interweaves the presentation of evolutionary principles with examples that illustrate how an evolutionary perspective enhances our understanding of disease. It discusses the theory of evolution by natural selection, the genetic basis of evolutionary change, evolutionary life history theory, and host-pathogen coevolution, and uses these concepts to provide new insights into diseases such as cystic fibrosis, cancer, sexually transmitted diseases, and malaria, incorporating the latest research in rapidly developing fields such as epigenetics and the study of the human microbiome. The book concludes with a discussion of the ways in which recent, culturally constructed changes in the human environment are increasing the prevalence of man-made diseases such as diabetes and cardiovascular diseases, and are exacerbating socioeconomic disparities in health. Just as evolutionary biology is concerned with populations and with changes in populations over time, evolutionary medicine is concerned with the health of populations. Evolution and Medicine emphasizes the role of demographic processes in evolution and disease, and stresses the importance of improving population health as a strategy for improving the health of individuals. This accessible text is written primarily for physicians, biomedical scientists, and both premedical and medical students, and will appeal to all readers with a background or interest in medicine.


The Oxford Handbook of Evolutionary Medicine

The Oxford Handbook of Evolutionary Medicine

Author: Martin Brüne

Publisher: Oxford University Press

Published: 2019-01-31

Total Pages: 967

ISBN-13: 0192506781

DOWNLOAD EBOOK

Medicine is grounded in the natural sciences, where biology stands out with regard to our understanding of human physiology and the conditions that cause dysfunction. Ironically though, evolutionary biology is a relatively disregarded field. One reason for this omission is that evolution is deemed a slow process. Indeed, the macroanatomical features of our species have changed very little in the last 300,000 years. A more detailed look, however, reveals that novel ecological contingencies, partly in relation to cultural evolution, have brought about subtle changes pertaining to metabolism and immunology, including adaptations to dietary innovations, as well as adaptations to the exposure to novel pathogens. Rapid pathogen evolution and evolution of cancer cells cause major problems for the immune system. Moreover, many adaptations to past ecologies have actually turned into risk factors for somatic disease and psychological disorder in our modern worlds (i.e. mismatch), among which epidemics of autoimmune diseases, cardiovascular diseases, diabetes and obesity, as well as several forms of cancer stand out. One could add depression, anxiety, and other psychiatric conditions to the list. The Oxford Handbook of Evolutionary Medicine is a compilation of up-to-date insights into the evolutionary history of ourselves as a species, exploring how and why our evolved design may convey vulnerability to disease. Written in a classic textbook style emphasising physiology and pathophysiology of all major organ systems, the Oxford Handbook of Evolutionary Medicine is valuable reading for students as well as scholars in the fields of medicine, biology, anthropology and psychology.


A Primer of Evolutionary Medicine

A Primer of Evolutionary Medicine

Author: Stephen Stearns

Publisher: Sinauer

Published: 2015-11-18

Total Pages: 0

ISBN-13: 9781605352602

DOWNLOAD EBOOK

Evolutionary Medicine is a textbook intended for use in undergraduate, graduate, medical school, and continuing medical education (CME) courses. Its professional illustrations and summaries of chapters and sections make its messages readily accessible.


Evidence-Based Evolutionary Medicine

Evidence-Based Evolutionary Medicine

Author: John S. Torday

Publisher: John Wiley & Sons

Published: 2018-05-03

Total Pages: 195

ISBN-13: 1118838335

DOWNLOAD EBOOK

A groundbreaking, evidence-based text to the growing field of evolutionary medicine Evidence-Based Evolutionary Medicine offers a comprehensive review of the burgeoning field of evolutionary medicine and explores vital topics such as evolution, ecology, and aging as they relate to mainstream medicine. The text integrates Darwinian principles and evidence-based medicine in order to offer a clear picture of the underlying principles that reflect how and why organisms have evolved on a cellular level. The authors—noted authorities in their respective fields—address evolutionary medicine from a developmental cell-molecular perspective. They explore the first principles of physiology that explain the generation of existing tissues, organs, and organ systems. The text offers an understanding of the overall biology as a vertically integrated whole, from unicellular to multicellular organisms. In addition, it addresses clinical diagnostic and therapeutic approaches, both traditional and cell-homeostatic. This groundbreaking text: • Offers a much-needed, logical, and fundamental approach to biology and medicine • Provides a clear explanation of complex physiology and pathophysiology • Integrates topics like evolution, ecology and aging into mainstream medicine, making them more relevant • Contains the first evidence-based text on evolutionary medicine Written for medical and graduate students in biology, physiology, anatomy, endocrinology, reproductive biology, medicine, pathology, systems biology, this vital resource offers a unique text of both biology as an integrated whole with universal properties; and of medicine seeing the individual as a whole, not an inventory of parts and diseases.


Evolution and Healing

Evolution and Healing

Author: Randolph M. Nesse

Publisher: Phoenix Illustrated

Published: 1996

Total Pages: 290

ISBN-13: 9781857995060

DOWNLOAD EBOOK

The first ever description of how evolutionary principles can be applied to questions of health and sickness.


Why We Get Sick

Why We Get Sick

Author: Randolph M. Nesse, MD

Publisher: Vintage

Published: 2012-02-08

Total Pages: 306

ISBN-13: 0307816001

DOWNLOAD EBOOK

The next time you get sick, consider this before picking up the aspirin: your body may be doing exactly what it's supposed to. In this ground-breaking book, two pioneers of the science of Darwinian medicine argue that illness as well as the factors that predispose us toward it are subject to the same laws of natural selection that otherwise make our bodies such miracles of design. Among the concerns they raise: When may a fever be beneficial? Why do pregnant women get morning sickness? How do certain viruses "manipulate" their hosts into infecting others? What evolutionary factors may be responsible for depression and panic disorder? Deftly summarizing research on disorders ranging from allergies to Alzheimer's, and form cancer to Huntington's chorea, Why We Get Sick, answers these questions and more. The result is a book that will revolutionize our attitudes toward illness and will intrigue and instruct lay person and medical practitioners alike.


Evolutionary Systems Biology

Evolutionary Systems Biology

Author: Orkun S. Soyer

Publisher: Springer Science & Business Media

Published: 2012-07-23

Total Pages: 459

ISBN-13: 1461435676

DOWNLOAD EBOOK

The book aims to introduce the reader to the emerging field of Evolutionary Systems Biology, which approaches classical systems biology questions within an evolutionary framework. An evolutionary approach might allow understanding the significance of observed diversity, uncover “evolutionary design principles” and extend predictions made in model organisms to others. In addition, evolutionary systems biology can generate new insights into the adaptive landscape by combining molecular systems biology models and evolutionary simulations. This insight can enable the development of more detailed mechanistic evolutionary hypotheses.


Evolutionary Thinking in Medicine

Evolutionary Thinking in Medicine

Author: Alexandra Alvergne

Publisher: Springer

Published: 2016-05-13

Total Pages: 374

ISBN-13: 3319297163

DOWNLOAD EBOOK

The aim of this edited book is to provide health professionals, across a wide variety of specialisms, with a targeted access to evolutionary medicine. Throughout the book, the views of both medical and evolutionary scientists on the latest relevant research is presented with a focus on practical implications. The inclusion of boxes explaining the theoretical background as well as both a glossary for technical terms and a lay summary for non- specialists enable medical researchers, public health professionals, policy makers, physicians, students, scholars and the public alike to quickly and easily access appropriate information. This edited volume is thus relevant to anyone keen on finding out how evolutionary medicine can improve the health and well-being of people.