This evidence-based guide on the use of radiotherapy in patients with common malignancies of the lung, esophagus, and thymus will help radiation oncologists to deliver optimal care within a multidisciplinary setting. Detailed information is provided on all aspects, from delineation of tumor volumes and organs at risk based on four-dimensional CT simulation through to the various advanced radiotherapy techniques, including stereotactic ablative radiotherapy (SABR), intensity-modulated radiation therapy (IMRT), tomotherapy, volumetric modulated arc therapy (VMAT), and proton therapy. Contouring, treatment planning, and treatment delivery are documented in a range of everyday cases, with illustrations of slice-by-slice delineations on planning CT images and finalized treatment plans based on detailed acceptance criteria. Numerous practical tips are highlighted, and relevant information is included on surgical techniques and systemic therapies. The book will facilitate decision making in the management of patients with common thoracic malignancies and assist in overcoming the challenges encountered in daily clinical practice.
Thoroughly revised and updated, this Fourth Edition is the most comprehensive, current reference on lung cancer, with contributions from the world's foremost surgeons, radiation oncologists, medical oncologists, pulmonologists, and basic scientists. Coverage includes complete information on combined modality treatments for small cell and non-small cell lung cancer and on complications of treatment and management of metastases. Emphasis is also given to early detection, screening, prevention, and new imaging techniques. This edition has expanded thoracic oncology chapters including thymus, mesothelioma, and mediastinal tumors, more detailed discussion of targeted agents, and state-of-the-art information on newer techniques in radiotherapy. Other highlights include more international contributors and greater discussion of changes in lung cancer management in each region of the world. A new editor, Giorgio Scagliotti, MD from the University of Turin, has coordinated the accounts of European activities. A companion website includes the full text online and an image bank.
Successful clinical use of intensity-modulated radiation therapy (IMRT) represents a significant advance in radiation oncology. Because IMRT can deliver high-dose radiation to a target with a reduced dose to the surrounding organs, it can improve the local control rate and reduce toxicities associated with radiation therapy. Since IMRT began being used in the mid-1990s, a large volume of clinical evidence of the advantages of IMRT has been collected. However, treatment planning and quality assurance (QA) of IMRT are complicated and difficult for the clinician and the medical physicist. This book, by authors renowned for their expertise in their fields, provides cumulative clinical evidence and appropriate techniques for IMRT for the clinician and the physicist. Part I deals with the foundations and techniques, history, principles, QA, treatment planning, radiobiology and related aspects of IMRT. Part II covers clinical applications with several case studies, describing contouring and dose distribution with clinical results along with descriptions of indications and a review of clinical evidence for each tumor site. The information presented in this book serves as a valuable resource for the practicing clinician and physicist.
Decision Making in Radiation Oncology is a reference book designed to enable radiation oncologists, including those in training, to make diagnostic and treatment decisions effectively and efficiently. The design is based on the belief that “a picture is worth a thousand words.” Knowledge is conveyed through an illustrative approach using algorithms, schemas, graphics, and tables. Detailed guidelines are provided for multidisciplinary cancer management and radiation therapy techniques. In addition to the attention-riveting algorithms for diagnosis and treatment, strategies for the management of disease at individual stages are detailed for all the commonly diagnosed malignancies. Clinical trials that have yielded “gold standard” treatment and their results are documented in the schemas. Moreover, radiation techniques, including treatment planning and delivery, are presented in an illustrative way. This groundbreaking publication is an essential tool for physicians in their daily clinical practice.
In this Handbook, a team of leading experts provide a comprehensive and up-to-date overview of the ever-changing field of radiation oncology. The publication is divided into three volumes, the first of which covers basics such as radiotherapy techniques, treatment documentation, clinical radiobiology, and patient management. In the second volume, all aspects of clinical radiation therapy are discussed in depth for the full range of tumor types. In order to ensure that the reader has a full understanding of cancer management in each scenario, information is also provided on diagnosis and classification, general management principles, the role of surgical and systemic therapy, and prognosis. The third volume focuses on medical physics, covering the mathematical and computer science background, biophysics, radiation physics, instrumentation, tracer kinetic modeling, pharmacokinetics and pharmacodynamics, radiation sources and detectors, biomedical engineering, imaging techniques, radiation treatment planning, and quality assurance. This book will be invaluable for all radiation oncologists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.
Breast cancer is the most common malignancy among the female population. With advances in systemic therapies and modern radiotherapy techniques, breast cancer patients can have a long life-expectancy. However, it is crucial that radiation therapy is carried out with minimum complications and with the utmost efficiency. Principles and Practice of Modern Radiotherapy Techniques in Breast Cancer provides practical and current theoretical knowledge to the planning and implementation of breast cancer radiation therapy. All aspects of breast cancer are covered, including epidemiology, molecular and biological basis and integrating systemic therapies during all steps of treatment. The illustrated section of this book identifies anatomical structures in daily practice by presenting target and critical structures in actual treatment positions. These images show and mark the anatomical points of the patient lying in the position that breast radiation therapy would be performed. This text serves as a valuable resource for clinicians, residents and fellows practicing and learning breast cancer radiotherapy.
“This is a high quality book with directions and guidelines on how to generate valid treatment plans in the modern era of radiation oncology. It is very useful for any student (dosimetry, therapy, physicist, or physician) who is entering a practical treatment planning rotation...It is written as a companion to the Handbook of Treatment Planning in Radiation Oncology, 2nd edition, Videtic et al. (Demos Medical Publishing, 2015), and pairs very well with it.” Score: 88, 3 Stars, Doody’s Medical Reviews “Comparing with earlier published books about radiotherapy treatment planning, which are prone to the pedagogical side as textbooks, this new book serves an unmet need as a pocket-sized book with details and up to date information for user’s quick resource for treatment planning knowledge... “Strategies for Radiation Therapy Treatment Planning” is a handy and essential reference for modern treatment planning. It is therefore recommended as a valuable book for the bookshelf and pocket of everyone involved in radiotherapy treatment planning.” -- Dr. Chengyu Shi of Memorial Sloan Kettering Cancer Center for Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. Strategies for Radiation Therapy Treatment Planning provides radiation oncologists, physicists, and dosimetrists with a step-by-step guide to implementing external beam treatment plans that meet clinical requirements for each major disease site. As a companion book to the Handbook of Treatment Planning in Radiation Oncology Second Edition, this book focuses on the technical aspects of treatment planning and the major challenges in creating highly conformal dose distributions, referenced to as treatment plans, for external beam radiotherapy. To overcome challenges associated with each step, leading experts at the Cleveland Clinic have consolidated their knowledge and experience of treatment planning techniques, potential pitfalls, and other difficulties to develop quality plans across the gamut of clinical scenarios in radiation therapy. The book begins with an overview of external beam treatment planning principles, inverse planning and advanced planning tools, and descriptions of all components in simulation and verification. Following these introductory chapters are disease-site examples, including central nervous system, head and neck, breast, thoracic, gastrointestinal, genitourinary, gynecologic, lymphoma, and soft tissue sarcoma. The book concludes with expert guidance on planning for pediatric cancers and how to tailor palliative plans. Essential for all radiation therapy team members, including trainees, this book is for those who wish to learn or improve their treatment planning skills and understand the different treatment planning processes, plan evaluation, and patient setup. KEY FEATURES: Provides basic principles of treatment planning Contains step-by-step, illustrated descriptions of the treatment planning process Discusses the pros and cons of advanced treatment planning tools, such as auto-planning, knowledge-based planning, and multi-criteria based planning Describes each primary treatment site from simulation, patient immobilization, and creation of various treatment plans to plan evaluations Includes instructive sample plans to highlight best practices
This is a highly practical resource about the specific technical aspects of delivering radiation treatment. Pocket-sized and well organized for ease of use, the book is designed to lead radiation oncology trainees and residents step by step through the basics of radiotherapy planning and delivery for all major malignancies. This second edition retains the valued features of the first edition-comprehensive yet concise, practical, evidence-based-while incorporating recent advances in the field. This includes expanded and updated discussions of SBRT for prostate and GI tumors, intraoperative.
Pocket Guide to Radiation Oncology is an efficient, no-frills guide to the basics of clinical radiation oncology. The chapters are packed with clinical pearls and tables covering treatment options, doses, side effects, target delineations, treatment planning, and other essentials. Chapters are organized by site-specific disease. Each chapter presents the must-know key points, including treatment options by stage, relevant technical considerations, and important items for follow-ups. This crucial material makes the book an ideal companion for the practicing physician during rounds and other clinical settings. The book's organized format also lends itself to quick review for the board or MOC exams, and it can serve as a handy reference during a case review at a tumor board. Key Features: The outline format and wealth of succinct tables make this a great quick reference Each chapter concludes with a list of selected, summarized studies relevant to the disease 51 disease-based chapters make it easy to find particular sites without having to sift through dense, broad text Supplemental sections at the end of the book provide quick access to normal tissue tolerance constraints as well as recommendations for managing symptoms after radiation therapy
GLOBAL EPIDEMIOLOGY OF CANCER Cancer is the second highest cause of death in the United States, and a leading cause of death globally. Our goals are to discuss the global epidemiology of various cancers, with detailed information on their prevalence, incidence, and clinical considerations. Epidemiology is the key to understanding the mortality and morbidity of cancer, and how we can prevent, diagnose, and treat the disease. Prevention of cancer is essential for saving lives. Prevalence and incidence of cancer are key factors that each government and population must be aware of. Advances in the study of cancer occur on a regular basis, and this book provides the latest insights about relationships between the disease and stem cells, tumorigenesis, molecular interactions, pathways, channels, and immunity. Global Epidemiology of Cancer: Diagnosis and Treatment meets the needs of readers by providing current information about epidemiology (including molecular epidemiology), diagnosis, and treatment. Providing logical, step-by-step information on various cancers, this book consolidates all of the most up-to-date information and data from verified studies on all different types of cancers in the United States and throughout the world. Chapters are presented so that each includes an overview, clinical manifestations, epidemiology, pathophysiology, etiology and risk factors, diagnosis, treatment, prevention, and prognosis. Global Epidemiology of Cancer: Diagnosis and Treatment will be invaluable to graduate and postgraduate students, including medical students; nurses; physician assistants; residents in oncology; public health students and allied health students.
