This work represents a sound introduction to the fundamental principles of infrared microspectroscopy (IMS). It describes how IMS is used to solve specific microanalytical problems in a variety of disciplines, including forensic analysis, art conservation, and geological, pharmaceutical and electronics research. The book discusses when and how to use special techniques such as line scanning, 3-dimensional imaging and attenuated total reflection and grazing-angle spectroscopy.
This work represents a sound introduction to the fundamental principles of infrared microspectroscopy (IMS) It describes how IMS is used to solve specific microanalytical problems in a variety of disciplines, including forensic analysis, art conservation, and geological, pharmaceutical and electronics research. The book discusses when and how to use special techniques such as line scanning, 3-dimensional imaging and attenuated total reflection and grazing-angle spectroscopy.
Containing focused, comprehensive coverage, Practical Guide to Interpretive Near-Infrared Spectroscopy gives you the tools necessary to interpret NIR spectra. The authors present extensive tables, charts, and figures with NIR absorption band assignments and structural information for a broad range of functional groups, organic compounds, and polymers. They include visual spectral representation of all major compound functional groupings and NIR frequency ranges. Organized by functional group type and chemical structure, based on standard compound classification, the chapters are easy to follow.
Written by a field insider with over 20 years experience in product development, application support, and field marketing for an ICP-MS manufacturer, the third edition of Practical Guide to ICP-MS: A Tutorial for Beginners provides an updated reference that was written specifically with the novice in mind. It presents a compelling story about ICP-MS and what it has to offer, showing this powerful ultra trace-element technique in the way it was intended—a practical solution to real-world problems. New to the third edition: New chapter: Emerging ICP-MS Application Areas – covers the three most rapidly growing areas: analysis of flue gas desulfurization wastewaters, fully automated analysis of seawater samples using online chemistry procedures, and characterization of engineered nanoparticles Discussion of all the new technology commercialized since the second edition. An updated glossary of terms with more than 100 new entries Examination of nonstandard sampling accessories, which are important for enhancing the practical capabilities of ICP-MS Insight into additional applications in the environmental, clinical/biomedical, and food chemistry fields as well as new directives from the United States Pharmacopeia (USP) on determining impurities in pharmaceuticals and dietary supplements using Chapters 232, 233 and 2232 Description of the most important analytical factors for selecting an ICP-MS system, taking into consideration more recent application demands This reference describes the principles and application benefits of ICP-MS in a clear manner for laboratory managers, analytical chemists, and technicians who have limited knowledge of the technique. In addition, it offers much-needed guidance on how best to evaluate capabilities and compare with other trace element techniques when looking to purchase commercial ICP-MS instrumentation.
Publication of a multi-author textbook on the biomedical applications of synchrotron infrared microspectroscopy was a central element in the workplan of the EU project DASIM (Diagnostic Applications of Synchrotron Infrared Microspectroscopy). The project involved nearly 70 scientists and clinicians from 9 European countries, including all synchrotron facilities that have or are planning an infrared beamline. Together with its international associates from the USA, Canada and Australia, the project brought together essentially all recognized experts in the field. The project aims were to coordinate international research effort and to disseminate the relevant information amongst biological researchers and health care professionals and this multi-author textbook was conceived as the most important measure towards the aim of dissemination. The field of biomedical applications of synchrotron IR microspectroscopy, which has recently seen unprecedented growth, is extremely interdisciplinary, involving synchrotron physicists, spectroscopists, biologists and clinicians, with associated difficulties in getting these experts to understand each other. This multi-author book, from leading world experts, presents all aspects of the field in language that all the disparate experts involved can understand. It demystifies the subject both for clinicians and biologists who find synchrotron physics difficult to understand and for physicists who find medical/biological terminology incomprehensible. The book focuses specifically on biomedical IR spectroscopy using synchrotron light sources with particular emphasis on understandable presentation of necessary background knowledge, digestible summaries of research progress and above all as a practical 'how to do it' guide for those working in or wishing to enter the field of biomedical synchrotron IR microspectroscopy and imaging. Key features of the book include:- * a 'Fundamentals' section, explaining the basics of synchrotrons and FTIR spectroscopy as well as the needs of clinicians and biologists with respect to these technologies * a 'Technical Aspects' section, going into depth on optical issues, sample preparation and study design/data analysis * case studies bringing together these 2 elements through practical examples * Raman microspectroscopy, as an alternative approach, is explored in depth * the foreword is written by Henry Mantsch and Gwynn Williams, the two undisputed experts in the fields of biomedical FTIR spectroscopy and synchrotron IR microspectroscopy respectively
Practical Sampling Techniques for Infrared Analysis provides a single-source guide to sample handling for routine analysis in infrared spectroscopy using commercially available instrumentation and accessories. Following a review of infrared spectroscopic theory, chapters consider individual techniques such as transmission methodology (e.g., solution cells, KBr pellets), internal reflectance, diffuse reflectance, photoacoustic FT-IR, infrared microscopy, GC/FT-IR, and quantitative analysis. In addition, two chapters elaborate on both typical and unusual samples and problems encountered in industrial laboratories and the process by which a spectroscopist chooses the most effective technique. Various short courses on infrared analysis are also listed. Practical Sampling Techniques for Infrared Analysis will be an important guide for all professional analytical chemists and technicians.
Practical Sampling Techniques for Infrared Analysis provides a single-source guide to sample handling for routine analysis in infrared spectroscopy using commercially available instrumentation and accessories. Following a review of infrared spectroscopic theory, chapters consider individual techniques such as transmission methodology (e.g., solution cells, KBr pellets), internal reflectance, diffuse reflectance, photoacoustic FT-IR, infrared microscopy, GC/FT-IR, and quantitative analysis. In addition, two chapters elaborate on both typical and unusual samples and problems encountered in industrial laboratories and the process by which a spectroscopist chooses the most effective technique. Various short courses on infrared analysis are also listed. Practical Sampling Techniques for Infrared Analysis will be an important guide for all professional analytical chemists and technicians.
Microscopy plays an integral role in the research and development of new medicines. Pharmaceutical Microscopy describes a wide variety of techniques together with numerous practical applications of importance in drug development. The first section presents general methods and applications with an emphasis on the physical science aspects. Techniques covered include optical crystallography, thermal microscopy, scanning electron microscopy, energy dispersive x-ray spectrometry, microspectroscopy (infrared and Raman), and particle size and shape by image analysis. The second section presents applications of these techniques to specific topics of pharmaceutical interest, including studies of polymorphism, particle size and shape analysis, and contaminant identification. Pharmaceutical Microscopy is designed for those scientists who must use these techniques to solve pharmaceutical problems but do not need to become expert microscopists. Consequently, each section has exercises designed to teach the reader how to use and apply the techniques in the book. Although the focus is on pharmaceutical development, workers in other fields such as food science and organic chemistry will also benefit from the discussion of techniques and the exercises. Provides comprehensive coverage of key microscopy techniques used in pharmaceutical development Helps the reader to solve specific problems in pharmaceutical quality assurance Oriented and designed for pharmaceutical scientists who need to use microscopy but are not expert microscopists Includes a large number of practical exercises to give the reader hands-on experience with the techniques Written by an author with 21 years of experience in the pharmaceutical industry
This book delineates practical, tested, general methods for ultraviolet, visible, and infrared spectrometry in clear language for novice users, and serves as a reference resource for advanced spectroscopists. Applied Spectroscopy includes important information and equations which will be referred to regularly. The book emphasizes reflectance and color measurements due to their common usage in todays spectroscopic laboratories, and contains methods for selectinga measurement technique as well as solar and color measurements. Written by experts in the field, this text covers spectrometry of new materials, ceramics, and textiles, and provides an appendix of practical reference data for spectrometry. Book topics include: Practical aspects of spectrometers and spectrometry; Sample preparation; Chemometrics and calibration practices; Reflectance measurements; Standard materials measurements An emphasis is placed on reflectance and color measurements due to their common usage in today's spectroscopic laboratories Methods for selecting a measurement technique are included as well as solar measurements and reference information on sources, detectors, optical fiber and window materials
