Personal Genomes
Author: Cold Spring Harbor Laboratory Press
Publisher:
Published: 2009
Total Pages: 0
ISBN-13: 9780879699277
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Author: Cold Spring Harbor Laboratory Press
Publisher:
Published: 2009
Total Pages: 0
ISBN-13: 9780879699277
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Publisher: Cold Spring Harbor Laboratory Press
Published: 2009-11-01
Total Pages: 74
ISBN-13: 9780879699277
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Published: 2011
Total Pages: 75
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Published: 2010
Total Pages:
ISBN-13: 9789990252583
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Published: 2010
Total Pages: 80
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Published: 2012
Total Pages: 131
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DOWNLOAD EBOOKAuthor: Cold Spring Harbor Laboratory Press
Publisher:
Published: 2008
Total Pages: 0
ISBN-13: 9780879698775
DOWNLOAD EBOOKAuthor: Cold Spring Harbor Laboratory Press
Publisher:
Published: 2008
Total Pages: 47
ISBN-13: 9780879698775
DOWNLOAD EBOOKAuthor: Hon Wai Leong
Publisher: Imperial College Press
Published: 2008
Total Pages: 145
ISBN-13: 1848162529
DOWNLOAD EBOOKResearch in the field of gene regulation is evolving rapidly in the ever-changing scientific environment. Advances in microarray techniques and comparative genomics have enabled more comprehensive studies of regulatory genomics. The study of genomic binding locations of transcription factors has enabled a more comprehensive modeling of regulatory networks. In addition, complete genomic sequences and comparison of numerous related species have demonstrated the conservation of non-coding DNA sequences, which often provide evidence for cis-regulatory binding sites. Systematic methods to decipher the regulatory mechanism are also crucial for corroborating these regulatory networks; key to these methods are motif discovery algorithms that can help predict cis-regulatory elements. These DNA-motif discovery programs are becoming more sophisticated and are beginning to leverage evidence from comparative genomics. These topics and more were discussed at the 3rd Annual RECOMB Workshop on Regulatory Genomics, which brought together more than 90 attendees and included about 22 excellent talks from leading researchers in the field. This proceedings volume contains ten selected, original manuscripts that were presented during the workshop.
Author: James Shreeve
Publisher: Ballantine Books
Published: 2007-12-18
Total Pages: 418
ISBN-13: 0307417069
DOWNLOAD EBOOKThe long-awaited story of the science, the business, the politics, the intrigue behind the scenes of the most ferocious competition in the history of modern science—the race to map the human genome. On May 10, 1998, biologist Craig Venter, director of the Institute for Genomic Research, announced that he was forming a private company that within three years would unravel the complete genetic code of human life—seven years before the projected finish of the U.S. government’s Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich. Calling his company Celera (from the Latin for “speed”), he assembled a small group of scientists in an empty building in Rockville, Maryland, and set to work. At the same time, the leaders of the government program, under the direction of Francis Collins, head of the National Human Genome Research Institute at the National Institutes of Health, began to mobilize an unexpectedly unified effort to beat Venter to the prize—knowledge that had the potential to revolutionize medicine and society. The stage was set for one of the most thrilling—and important—dramas in the history of science. The Genome War is the definitive account of that drama—the race for the greatest prize biology has had to offer, told by a writer with exclusive access to Venter’s operation from start to finish. It is also the story of how one man’s ambition created a scientific Camelot where, for a moment, it seemed that the competing interests of pure science and commercial profit might be gloriously reconciled—and the national repercussions that resulted when that dream went awry.