Permeability and Stability of Lipid Bilayers

Permeability and Stability of Lipid Bilayers

Author: E. Anibal Disalvo

Publisher: CRC Press

Published: 2017-12-14

Total Pages: 298

ISBN-13: 1351425382

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This book presents a comprehensive and coherent picture of how molecules diffuse across a liquid that is, on average, only two molecules thick. It begins by characterizing bilayers structurally, using X-ray diffraction, and then mechanically by measuring elastic moduli and mechanisms of failure. Emphasis is placed on the stability and mechanical properties of plant membranes that are subject to very large osmotic and thermal stresses. Using this information, the transport of molecules of increasing complexity across bilayers is analyzed.


Thermal Biophysics of Membranes

Thermal Biophysics of Membranes

Author: Thomas Heimburg

Publisher: John Wiley & Sons

Published: 2008-02-08

Total Pages: 378

ISBN-13: 3527611606

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An overview of recent experimental and theoretical developments in the field of the physics of membranes, including new insights from the past decade. The author uses classical thermal physics and physical chemistry to explain our current understanding of the membrane. He looks at domain and 'raft' formation, and discusses it in the context of thermal fluctuations that express themselves in heat capacity and elastic constants. Further topics are lipid-protein interactions, protein binding, and the effect of sterols and anesthetics. Many seemingly unrelated properties of membranes are shown to be intimately intertwined, leading for instance to a coupling between membrane state, domain formation and vesicular shape. This also applies to non-equilibrium phenomena like the propagation of density pulses during nerve activity. Also included is a discussion of the application of computer simulations on membranes. For both students and researchers of biophysics, biochemistry, physical chemistry, and soft matter physics.


Cells: Molecules and Mechanisms

Cells: Molecules and Mechanisms

Author: Eric Wong

Publisher: Axolotl Academic Publishing

Published: 2009

Total Pages: 283

ISBN-13: 0985226110

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"Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology."--Open Textbook Library.


Mesoscale Chemistry

Mesoscale Chemistry

Author: National Research Council

Publisher: National Academies Press

Published: 2015-08-06

Total Pages: 229

ISBN-13: 030937331X

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In the last few decades great strides have been made in chemistry at the nanoscale, where the atomic granularity of matter and the exact positions of individual atoms are key determinants of structure and dynamics. Less attention, however, has been paid to the mesoscale-it is at this scale, in the range extending from large molecules (10 nm) through viruses to eukaryotic cells (10 microns), where interesting ensemble effects and the functionality that is critical to macroscopic phenomenon begins to manifest itself and cannot be described by laws on the scale of atoms and molecules alone. To further explore how knowledge about mesoscale phenomena can impact chemical research and development activities and vice versa, the Chemical Sciences Roundtable of the National Research Council convened a workshop on mesoscale chemistry in November 2014. With a focus on the research on chemical phenomena at the mesoscale, participants examined the opportunities that utilizing those behaviors can have for developing new catalysts, adding new functionality to materials, and increasing our understanding of biological and interfacial systems. The workshop also highlighted some of the challenges for analysis and description of mesoscale structures. This report summarizes the presentations and discussion of the workshop.


Cholesterol in Membrane Models

Cholesterol in Membrane Models

Author: Leonard X. Finegold

Publisher: CRC Press

Published: 1992-12-15

Total Pages: 298

ISBN-13: 9780849342073

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Cholesterol in Membrane Models provides the most recent summary available of basic molecular models and experiments in models of biological membranes. The book introduces the cell biology of cholesterol and covers the modeling of cholesterol in model membranes by the mean field and Monte Carlo theoretical methods. The experimental movement of cholesterol into model membranes and phase diagrams of cholesterol in these membranes by nuclear magnetic resonance and by thermal techniques using different lipid chain lengths are discussed. Light and electron microscopy that explore the spatial distribution of cholesterol in the model membrane are covered. The book also examines the use of infrared/Raman and neutron spectroscopy. Cholesterol in Membrane Models is an excellent learning resource, research tool, and reference for a wide range of experimental and theoretical scientists, including cellular biologists, biophysicists, biochemists, and molecular modelers.


The Giant Vesicle Book

The Giant Vesicle Book

Author: Rumiana Dimova

Publisher: CRC Press

Published: 2019-11-19

Total Pages: 1168

ISBN-13: 1351648551

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Giant vesicles are widely used as a model membrane system, both for basic biological systems and for their promising applications in the development of smart materials and cell mimetics, as well as in driving new technologies in synthetic biology and for the cosmetics and pharmaceutical industry. The reader is guided to use giant vesicles, from the formation of simple membrane platforms to advanced membrane and cell system models. It also includes fundamentals for understanding lipid or polymer membrane structure, properties and behavior. Every chapter includes ideas for further applications and discussions on the implications of the observed phenomena towards understanding membrane-related processes. The Giant Vesicle Book is meant to be a road companion, a trusted guide for those making their first steps in this field as well as a source of information required by experts. Key Features • A complete summary of the field, covering fundamental concepts, practical methods, core theory, and the most promising applications • A start-up package of theoretical and experimental information for newcomers in the field • Extensive protocols for establishing the required preparations and assays • Tips and instructions for carefully performing and interpreting measurements with giant vesicles or for observing them, including pitfalls • Approaches developed for investigating giant vesicles as well as brief overviews of previous studies implementing the described techniques • Handy tables with data and structures for ready reference


Water in Biological and Chemical Processes

Water in Biological and Chemical Processes

Author: Biman Bagchi

Publisher: Cambridge University Press

Published: 2013-11-14

Total Pages: 383

ISBN-13: 1107037298

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A unified overview of the dynamical properties of water and its unique and diverse role in biological and chemical processes.


Cell Biology by the Numbers

Cell Biology by the Numbers

Author: Ron Milo

Publisher: Garland Science

Published: 2015-12-07

Total Pages: 400

ISBN-13: 1317230698

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A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid


Oxygen Transport to Tissue XXXIX

Oxygen Transport to Tissue XXXIX

Author: Howard J. Halpern

Publisher: Springer

Published: 2017-07-06

Total Pages: 427

ISBN-13: 3319552317

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This volume presents all aspects of delivery of oxygen to tissues and tumors in peer reviewed short articles. Both overview and the most recent, advanced techniques for oxygen measurement are presented. Articles and peer reviewers include those from leaders in their field. Topics such as molecular signaling in the organismal and tumor response to low levels of local oxygenation, hypoxia inducible factor (HIF) , cancer metabolism, individual human and animal response to oxygen changes monitored by optical/near infrared spectroscopy/ tomography to novel electron resonance spectroscopy and spectroscopic imaging, instrumentation, progress in blood substitute research, retinal physiology, cellular hypoxia, mitochondrial function; brain oxygenation and function; oxygen transport in sports, hypoxia in diseases and clinical care. Chapters 10 and 19 of this book are open access under a CC BY 4.0 license.