This volume presents papers from the 8th International Symposium on Environmental Vibration and Transportation Geodynamics (ISEV2018). It covers the latest advances in the areas of environmental vibrations, and its impact on dynamic vehicular loading, transportation infrastructures and the built environment. This volume will be of interest to policy-makers and researchers in academia, industry and government.
Since the 1990s five books on ‘Applications of Computational Mechanics in Geotechnical Engineering’ have been published. Innovative Numerical Modelling in Geomechanics is the 6th and final book in this series, and contains papers written by leading experts on computational mechanics. The book treats highly relevant topics in the field of geotechnics, such as environmental geotechnics, open and underground excavations, foundations, embankments and rockfill dams, computational systems and oil geomechanics. Special attention is paid to risk in geotechnical engineering, and to recent developments in applying Bayesian networks and Data Mining techniques. Innovative Numerical Modelling in Geomechanics will be of interest to civil, mining and environmental engineers, as well as to engineering geologists. The book will also be useful for academics and researchers involved in geotechnics.
Extracellular Vesicles, Volume 645 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Genetic labeling of extracellular vesicle exosomes for studying biogenesis and uptake in living mammalian cells, Fluorescent Labeling of Extracellular Vesicles, Isolation of extracellular vesicles from lymph, Transgenic rats for tracking body fluid/tissue-derived extracellular vesicles, Isolation of amniotic extracellular vesicles, Urinary extracellular vesicle isolation, Immunocapture-based ELISA to Characterize and Quantify Extracellular Vesicles in Both Cell Culture Supernatants and Body Fluids, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series
The Okavango Delta, a globally renowned wetland, is characterised by a mosaic of meandering watercourses, floodplains and islands, and is home to a variety of wildlife and vegetation species. It is a major source of livelihoods for the local communities and also an important attraction for tourism, the second most important economic activity in Botswana after diamonds, contributing 5% to the gross domestic product (GDP). As a globally renowned Ramsar Site and major tourist attraction, the Okavango Delta is a resource of national, regional and international importance. This book examines the results of empirical micro-level studies undertaken in the Okavango Delta and contributes to the formulation of relevant policies for sustainable development in the Okavango Delta.
Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.
Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. - Introduces the MSC-exosome mediated cell-cell communication - Covers the major functional benefits in current MSC-derived exosome studies - Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies
Gain a stronger foundation with optimal ground improvement Before you break ground on a new structure, you need to analyze the structure of the ground. Expert analysis and optimization of the geo-materials on your site can mean the difference between a lasting structure and a school in a sinkhole. Sometimes problematic geology is expected because of the location, but other times it's only unearthed once construction has begun. You need to be able to quickly adapt your project plan to include an improvement to unfavorable ground before the project can safely continue. Principles and Practice of Ground Improvement is the only comprehensive, up-to-date compendium of solutions to this critical aspect of civil engineering. Dr. Jie Han, registered Professional Engineer and preeminent voice in geotechnical engineering, is the ultimate guide to the methods and best practices of ground improvement. Han walks you through various ground improvement solutions and provides theoretical and practical advice for determining which technique fits each situation. Follow examples to find solutions to complex problems Complete homework problems to tackle issues that present themselves in the field Study design procedures for each technique to simplify field implementation Brush up on modern ground improvement technologies to keep abreast of all available options Principles and Practice of Ground Improvement can be used as a textbook, and includes Powerpoint slides for instructors. It's also a handy field reference for contractors and installers who actually implement plans. There are many ground improvement solutions out there, but there is no single right answer to every situation. Principles and Practice of Ground Improvement will give you the information you need to analyze the problem, then design and implement the best possible solution.
The largest high-level encyclopedia on molecular medicine is now publishing a topical volume on Nanomedicine. The long awaited volume gives a comprehensive overview on nanomaterials in drug delivery, imaging and as therapeutics.
The enormous expansion seen over the last decade in the mammo graphic detection of breast cancer lesions, especially the use of screen ing procedures for the early detection of clinically unsuspected tumors, has made it necessary to summarize the experience made by various centers in the world. The 2nd International Copenhagen Symposium on Detection of Breast Cancer afforded an opportunity of gathering scientists from all over the world to discuss the various problems of early breast cancer detection with special reference to screening procedures. This book forms a synthesis of the information presented by leading scientists from many of the world's mammo graphic centers, particularly those in Sweden and the USA. Hence, the reader will have the opportunity to study the outstanding work carried out by various institutes and centers of breast cancer screening. It is our sincere hope that a study of this volume will encourage other scientists to join in the work on screening procedures. S. Brunner B. Langfeldt P. E. Andersen Contents S. A. Feig: 1 Hypothetical Breast Cancer Risk from Mammography S. A. Feig: Benefits and Risks of Mammography 11 R. L. Egan and M. B. McSweeney: Multicentric Breast Carcinoma . . . . . . . . . . . . . . . . . . . . . . . . 28 M. B. McSweeney and R. L. Egan: Breast Cancer in the Younger Patient: A Preliminary Report 36 M. B. McSweeney and R. L. Egan: Bilateral Breast Carcinoma . . . . . . . . . . . . . . . . . . . . . . . . . . . ' 41 N. Bjurstam: The Radiographic Appearance of Normal and Metastatic Axillary Lymph Nodes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 M. Moskowitz, S. A. Feig, C. Cole-Beuglet, S. H.
This new edition keeps you up to date with the exciting new developments in treating cerebrovascular disorders. Comprehensive and practical, it surveys methods for accurate stroke diagnosis necessary for you to make appropriate therapeutic decisions.
