Evidence-based medicine has shown for many years that homozygous mutations of the HFE gene H63D are by no means negligible. Not only can it provoke, usually after a second hit, rather mild classical hemochromatosis, but it can also cause numerous other disorders of iron metabolism, such as Oslo-Syndrome. The latter is a severe disease which leads to multiple organ damages and is - for reasons that remain in the dark - not as known as Wilson's disease which is a very similar syndrome caused by copper.
"This case study in the psychology of a community under chronic attack takes on broader significance at a time when even traditionally safe and secure societies such as the United States are confronting the psychological challenges posed by terrorist assaults."--Jacket.
Oslo Syndrome (in research still known as H63D Syndrome) is a worldwide health problem in the field of iron metabolism disorders. After scientists from all over the world joined together in 2019 to form the H63D Syndrome Consortium, the consensus paper "H63D Syndrome" was adopted at a meeting in Oslo in December 2019. On the occasion of the 2022 conference the syndrome was renamed Oslo Syndrome for clinical settings. It is available in bookshops for a symbolic price. Also free of charge directly from the consortium.
This volume covers aspects of sudden infant and early childhood death, ranging from issues with parental grief, to the most recent theories of brainstem neurotransmitters. It also deals with the changes that have occurred over time with the definitions of SIDS (sudden infant death syndrome), SUDI (sudden unexpected death in infancy) and SUDIC (sudden unexpected death in childhood). The text will be indispensable for SIDS researchers, SIDS organisations, paediatric pathologists, forensic pathologists, paediatricians and families, in addition to residents in training programs that involve paediatrics. It will also be of use to other physicians, lawyers and law enforcement officials who deal with these cases, and should be a useful addition to all medical examiner/forensic, paediatric and pathology departments, hospital and university libraries on a global scale. Given the marked changes that have occurred in the epidemiology and understanding of SIDS and sudden death in the very young over the past decade, a text such as this is very timely and is also urgently needed.
The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.
This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.
Part of the Jewish Encounter series As might be expected from this fiercely provocative writer, David Mamet’s interest in anti-Semitism is not limited to the modern face of an ancient hatred but encompasses as well the ways in which many Jews have themselves internalized that hatred. Using the metaphor of the Wicked Son at the Passover seder—the child who asks, “What does this story mean to you?”—Mamet confronts what he sees as an insidious predilection among some Jews to seek truth and meaning anywhere—in other religions, in political movements, in mindless entertainment—but in Judaism itself. At the same time, he explores the ways in which the Jewish tradition has long been and still remains the Wicked Son in the eyes of the world. Written with the searing honesty and verbal brilliance that is the hallmark of Mamet’s work, The Wicked Son is a scathing look at one of the most destructive and tenacious forces in contemporary life, a powerfully thought-provoking and important book.
A provocative look at the rise of youth culture, the worship of perpetual adolescence, and the sorry spectacle of adults shirking the responsibilities of maturity. Firebrand conservative columnist Diana West looks at the mess America is in and wonders "Where did all the grown-ups go?" Diana West sees a US filled with middle-age guys playing air guitar and thinks "No wonder we can't stop Islamic terrorism." She sees a landscape littered with Baby Britneys, Moms Who Mosh, and Dads too "young" to call themselves "mister" and wonders "Is there a single adult left anywhere?" But, the grown-ups are all gone. The disease that killed them was incubated in the sixties to a rock-and-roll score, took hold in the seventies with the help of multicultralism and left us with a nation of eternal adolescents who can't decide between "good" and "bad", a generation who can't say "no". With insightful wit, Diana West takes readers on an odyssey through culture and politics, from the rise of rock ‘n' roll to the rise of multiculturalism, from the loss of identity to the discovery of "diversity," from the emasculation of the heroic ideal to the "PC"-ing of "Mary Poppins," all the while building a compelling case against the childishness that is subverting the struggle against jihadist Islam in a mixed-up, post-9/11 world. From the inability to nix a sixteen year-old's request for Marilyn Manson concert tickets to offering adolescents parentally-funded motel rooms on prom night to rationalizing murderous acts of Islamic suicide bombers with platitudes of cultural equivalence, West sees us on a slippery slope that's lead to a time when America has forgotten its place in the world. The result of such indecisiveness is, ultimately, the end of Western civilization as we know it. Diana West serves up a provocative critique of our dangerously indecisive world leavened with humor and shot through with insight.
Completing his acclaimed trilogy on the history of Israel, Leslie Stein brings readers right up to contemporary events in Israel Since the Six-Day War. Stein vividly chronicles Israel's wars and military engagements, but he also incorporates fascinating assessments of many other issues, including Israel’s economic development, the nature of the PLO and Palestinian Authority, and Israeli settlements in the West Bank and Gaza. Furthermore, Stein explores broader social issues, such as extremist Jewish movements and the varying fortunes of migrants from Russia and Ethiopia, to convey clearly a sense of the diversity and complexity of modern Israel. Wide-ranging and judicious, Stein's cogent and compellingly readable account of Israel’s recent past will engage students and general readers alike.
