The NEURON Book

The NEURON Book

Author: Nicholas T. Carnevale

Publisher: Cambridge University Press

Published: 2006-01-12

Total Pages: 399

ISBN-13: 1139447831

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The authoritative reference on NEURON, the simulation environment for modeling biological neurons and neural networks that enjoys wide use in the experimental and computational neuroscience communities. This book shows how to use NEURON to construct and apply empirically based models. Written primarily for neuroscience investigators, teachers, and students, it assumes no previous knowledge of computer programming or numerical methods. Readers with a background in the physical sciences or mathematics, who have some knowledge about brain cells and circuits and are interested in computational modeling, will also find it helpful. The NEURON Book covers material that ranges from the inner workings of this program, to practical considerations involved in specifying the anatomical and biophysical properties that are to be represented in models. It uses a problem-solving approach, with many working examples that readers can try for themselves.


Brain Informatics

Brain Informatics

Author: Mufti Mahmud

Publisher: Springer Nature

Published: 2020-09-18

Total Pages: 384

ISBN-13: 3030592774

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This book constitutes the refereed proceedings of the 13th International Conference on Brain Informatics, BI 2020, held in Padua, Italy, in September 2020. The conference was held virtually due to the COVID-19 pandemic. The 33 full papers were carefully reviewed and selected from 57 submissions. The papers are organized in the following topical sections: cognitive and computational foundations of brain science; investigations of human information processing systems; brain big data analytics, curation and management; informatics paradigms for brain and mental health research; and brain-machine intelligence and brain-inspired computing.


Neuroscience Databases

Neuroscience Databases

Author: Rolf Kötter

Publisher: Springer Science & Business Media

Published: 2003

Total Pages: 340

ISBN-13: 9781402071652

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Neuroscience Databases: A Practical Guide is the first book providing a comprehensive overview of these increasingly important databases. This volume makes the results of the Human Genome Project and other recent large-scale initiatives in the neurosciences available to a wider community. It extends the scope of bioinformatics from the molecular to the cellular, microcircuitry and systems levels, dealing for the first time with complex neuroscientific issues and leading the way to a new culture of data sharing and data mining necessary to successfully tackle neuroscience questions. Aimed at the novice user who wants to access the data, it provides clear and concise instructions on how to download the available data sets and how to use the software with a minimum of technical detail with most chapters written by the database creators themselves. Key databases and topics include: -Neuroinformatics for C. Elegans; -Gene Expression Patterns; -Functional Analyses of Olfactory Receptors -Protein-Protein Interactions; -Web-Based Neuronal Archives; -Neuronal and Network Modeling; -Storage and Retrieval of Experimental Data for Biophysically Realistic Modeling; -Analysis of Spike Trains; -Neural Connectivity Patterns; -Software Tools for Neuroimaging; -Data Management, Inspection and Sharing.


Brain Transcriptome

Brain Transcriptome

Author:

Publisher: Academic Press

Published: 2014-08-26

Total Pages: 0

ISBN-13: 9780128011058

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Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume, concentrates on the brain transcriptome.


Clinical Neurotechnology meets Artificial Intelligence

Clinical Neurotechnology meets Artificial Intelligence

Author: Orsolya Friedrich

Publisher: Springer Nature

Published: 2021-03-03

Total Pages: 232

ISBN-13: 3030645908

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Neurotechnologies such as brain-computer interfaces (BCIs), which allow technical devices to be used with the power of thought or concentration alone, are no longer a futuristic dream or, depending on the viewpoint, a nightmare. Moreover, the combination of neurotechnologies and AI raises a host of pressing problems. Now that these technologies are about to leave the laboratory and enter the real world, these problems and implications can and should be scrutinized. This volume brings together scholars from a wide range of academic disciplines such as philosophy, law, the social sciences and neurosciences, and is unique in terms of both its focus and its methods. The latter vary considerably, and range from philosophical analysis and phenomenologically inspired descriptions to legal analysis and socio-empirical research. This diversified approach allows the book to explore the entire spectrum of philosophical, normative, legal and empirical dimensions of intelligent neurotechnologies. Philosophical and legal analyses of normative problems are complemented by a thorough empirical assessment of how BCIs and other forms of neurotechnology are being implemented, and what their measurable implications are. To take a closer look at specific neurotechnologies, a number of applications are addressed. Case studies, previously unidentified issues, and normative insights on these cases complement the rich portrait this volume provides. Clinicians, philosophers, lawyers, social scientists and engineers will greatly benefit from the collection of articles compiled in this book, which will likely become a standard reference work on the philosophy of intelligent neurotechnologies.


Introduction to Statistical Thought

Introduction to Statistical Thought

Author: Michael Lavine

Publisher: Orange Grove Text Plus

Published: 2009-09-24

Total Pages: 0

ISBN-13: 9781616100483

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This free PDF textbook is intended as an upper level undergraduate or introductory graduate textbook in statistical thinking. It is best suited to students with a good knowledge of calculus and the ability to think abstractly. The focus of the text is the ideas that statisticians care about as opposed to technical details of how to put those ideas into practice. Another unusual aspect is the use of statistical software as a pedagogical tool. That is, instead of viewing the computer merely as a convenient and accurate calculating device, the book uses computer calculation and simulation as another way of explaining and helping readers understand the underlying concepts. The book is written with the statistical language R embedded throughout. R software and accompanying manuals are available for free download from http: //www.r-project.or


Cellular Electron Microscopy

Cellular Electron Microscopy

Author: J. Richard McIntosh

Publisher: Elsevier

Published: 2011-09-02

Total Pages: 878

ISBN-13: 0080475035

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Recent advances in the imaging technique electron microscopy (EM) have improved the method, making it more reliable and rewarding, particularly in its description of three-dimensional detail. Cellular Electron Microscopy will help biologists from many disciplines understand modern EM and the value it might bring to their own work. The book's five sections deal with all major issues in EM of cells: specimen preparation, imaging in 3-D, imaging and understanding frozen-hydrated samples, labeling macromolecules, and analyzing EM data. Each chapter was written by scientists who are among the best in their field, and some chapters provide multiple points of view on the issues they discuss. Each section of the book is preceded by an introduction, which should help newcomers understand the subject. The book shows why many biologists believe that modern EM will forge the link between light microscopy of live cells and atomic resolution studies of isolated macromolecules, helping us toward the goal of an atomic resolution understanding of living systems. - Updates the numerous technological innovations that have improved the capabilities of electron microscopy - Provides timely coverage of the subject given the significant rise in the number of biologists using light microscopy to answer their questions and the natural limitations of this kind of imaging - Chapters include a balance of "how to", "so what" and "where next", providing the reader with both practical information, which is necessary to use these methods, and a sense of where the field is going


Computational Neuroanatomy

Computational Neuroanatomy

Author: Giorgio A. Ascoli

Publisher: Springer Science & Business Media

Published: 2002-07-01

Total Pages: 466

ISBN-13: 1592592759

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In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models.


Theoretical Neuroscience

Theoretical Neuroscience

Author: Peter Dayan

Publisher: MIT Press

Published: 2005-08-12

Total Pages: 477

ISBN-13: 0262541858

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Theoretical neuroscience provides a quantitative basis for describing what nervous systems do, determining how they function, and uncovering the general principles by which they operate. This text introduces the basic mathematical and computational methods of theoretical neuroscience and presents applications in a variety of areas including vision, sensory-motor integration, development, learning, and memory. The book is divided into three parts. Part I discusses the relationship between sensory stimuli and neural responses, focusing on the representation of information by the spiking activity of neurons. Part II discusses the modeling of neurons and neural circuits on the basis of cellular and synaptic biophysics. Part III analyzes the role of plasticity in development and learning. An appendix covers the mathematical methods used, and exercises are available on the book's Web site.