OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test

Author: OECD

Publisher: OECD Publishing

Published: 2016-07-29

Total Pages: 19

ISBN-13: 926426440X

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This screening Test Guideline describes the effects of a test chemical on male and female reproductive performance. It has been updated with endocrine disruptor endpoints, in particular measure of anogenital distance and male nipple retention in pups and thyroid examination.

Food Safety Assessment Of Pesticide Residues
Food Safety Assessment Of Pesticide Residues

Author: Arpad Ambrus

Publisher: World Scientific

Published: 2017-01-05

Total Pages: 568

ISBN-13: 1786341700

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Pesticides are now accepted as an integral part of modern agricultural production. This book provides analysis of the steps taken by national and international bodies working towards a cohesive global strategy for evaluating the safety of residues in food that result from approved pesticide uses. Also described is the role of the UN Food and Agriculture Organization (FAO), World Health Organization (WHO) and Codex Alimentarius in developing standards that protect the health of the consumers and ensure fair practices in the food trade. It goes on to look at the promotion of good agricultural practice in the use of pesticides and the need for control in their practical use. These include sampling, testing the compliance of marketed products against legal limits and verifying the effectiveness of the safety-based regulatory measures. This is a specialist book for those looking to go into the field of international food safety, for students and lecturers studying the topic, for policy makers working on public health and agricultural issues, and personnel responsible for taking samples and performing the analysis of pesticide formulations and residues.

Translational Toxicology and Therapeutics
Translational Toxicology and Therapeutics

Author: Michael D. Waters

Publisher: John Wiley & Sons

Published: 2018-01-04

Total Pages: 790

ISBN-13: 1119023602

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Written by leading research scientists, this book integrates current knowledge of toxicology and human health through coverage of environmental toxicants, genetic / epigenetic mechanisms, and carcinogenicity. Provides information on lifestyle choices that can reduce cancer risk Offers a systematic approach to identify mutagenic, developmental and reproductive toxicants Helps readers develop new animal models and tests to assess toxic impacts of mutation and cancer on human health Explains specific cellular and molecular targets of known toxicants operating through genetic and epigenetic mechanisms

Food Toxicology
Food Toxicology

Author: Debasis Bagchi

Publisher: CRC Press

Published: 2016-11-25

Total Pages: 575

ISBN-13: 1498708757

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Food toxicology studies how natural or synthetic poisons and toxicants in diverse food products cause harmful, detrimental, or adverse side effects in living organisms. Food toxicology is an important consideration as food supply chain is becoming more multinational in origin, and any contamination or toxic manifestation may cause serious, wide-spread adverse health effects. Food Toxicology covers various aspects of food safety and toxicology, including the study of the nature, properties, effects, and detection of toxic substances in food and their disease manifestations in humans. It will also include other aspects of consumer product safety. The first two chapters discuss the measurement of toxicants and toxicity and the importance of dose-response in food toxicology. Additional chapters discuss the aspects of food associated carcinogenesis and food-derived chemical carcinogenesis, food allergy, pathogens associated with fruits and vegetables, and the detrimental effects of radionuclides exposure. The chapters also cover the most important heavy metal contaminants, namely mercury, lead and vanadium, and Fluoride toxicity, which is extensively discussed in its own chapter. Toxicologists, scientists, researchers in food toxicology, nutritionists, and public health care professionals will find valuable information in this book on all possible intricate areas of food toxicology.

Developmental and Reproductive Toxicology
Developmental and Reproductive Toxicology

Author: Ronald D Hood

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 872

ISBN-13: 1841848212

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Completely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers e

Principles and Methods of Toxicology
Principles and Methods of Toxicology

Author: A. Wallace Hayes

Publisher: CRC Press

Published: 2007-09-25

Total Pages: 2296

ISBN-13: 1420005421

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Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanis