This Test Guideline is designed to be used for assessing the effects of chemicals on the reproductive output of the enchytraeid worm, Enchytraeus albidus Henle 1873, in soil. Adult enchytraeid worms are exposed to a range of concentrations of the ...
This Test Guideline is designed to be used for assessing the effects of chemicals on the reproductive output of the enchytraeid worm, Enchytraeus albidus Henle 1873, in soil.
This Test Guideline describes a method to assess the effects of chemical substances in soil on the reproductive output of the soil mite species Hypoaspis (Geolaelaps) aculeifer Canestrini (Acari: Laelapidae). It can be used for water soluble or ...
This Test Guideline describes a method to estimate the developmental toxicity of a test chemical to the dung dwelling life stages of dung-dependent dipteran species.
Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanisms. While the vastness of the field and the rapid accumulation of data may preclude the possibility of absorbing and retaining more than a fraction of the available information, a solid understanding of the underlying principles is essential. Extensively revised and updated with four new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. The book examines each method or procedure from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a broader and more diverse treatment of the ever-changing and expanding field of toxicology. Maintaining the high-quality information and organizational framework that made the previous editions so successful, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology.
Soils are receptacles for a wide range of hazardous chemicals generated by human activities. Whether or not this contamination is deliberate, accurate toxicity assessments are important for health and economic reasons. Soil Ecotoxicology discusses the sources, fate, and transport of hazardous chemicals in soils. The fate (biodegradation and modeling) and the potential impacts of pesticides on soil ecosystems are emphasized, and methodologies for performing toxicity assessments are provided.
Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.
An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simple” molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology.
We are proposing this comprehensive volume aimed at bridging and bonding of the theory and practical experiences for the elimination of a broad range of pollutants from various types of water and soil utilizing innovative nanotechnologies, biotechnologies and their possible combinations. Nowadays, a broad range of contaminants are emerging from the industry (and also representing old ecological burdens). Accidents and improper wastewater treatment requires a fast, efficient and cost-effective approach. Therefore, several innovative technologies of water and soil treatments have been invented and suggested in a number of published papers. Out of these, some nanotechnologies and biotechnologies (and possibly also their mutual combinations) turned out to be promising for practical utilization – i.e., based on both extensive laboratory testing and pilot-scale verification. With respect to the diverse character of targeted pollutants, the key technologies covered in this book will include oxidation, reduction, sorption and/or biological degradation. In relation to innovative technologies and new emerging pollutants mentioned in this proposed book, an important part will also cover the ecotoxicity of selected pollutants and novel nanomaterials used for remediation. Thus, this work will consist of 8 sections/chapters with a technical appendix as an important part of the book, where some technical details and standardized protocols will be clearly presented for their possible implementation at different contaminated sites. Although many previously published papers and books (or book chapters) are devoted to some aspects of nano-/biotechnologies, here we will bring a first complete and comprehensive treatise on the latest progress in innovative technologies with a clear demonstration of the applicability of particular methods based on results of the authors from pilot tests (i.e., based on the data collected within several applied projects, mainly national project “Environmentally friendly nanotechnologies and biotechnologies in water and soil treatment” of the Technology Agency of the Czech Republic, and 7FP project NANOREM: “Taking Nanotechnological Remediation Processes from Lab Scale to End User Applications for the Restoration of a Clean Environment”). This multidisciplinary book will be suitable for a broad audience including environmental scientists, practitioners, policymakers and toxicologists (and of course graduate students of diverse fields – material science, chemistry, biology, geology, hydrogeology, engineering etc.).
The OECD Guidelines for the Testing of Chemicals are a collection of internationally agreed methods for testing the safety of chemicals and chemical preparations, including pesticides and industrial chemicals. This 2005 update contains 11 new and 3 revised guidelines.