Handbook of Innovations in Central Nervous System Regenerative Medicine

Handbook of Innovations in Central Nervous System Regenerative Medicine

Author: António Salgado

Publisher: Elsevier

Published: 2020-06-10

Total Pages: 712

ISBN-13: 0128180854

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Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. - Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance - Discusses the limitations of present therapies used in the clinics - Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies - Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path


New approaches for central nervous system rehabilitation

New approaches for central nervous system rehabilitation

Author: Pawel Kiper

Publisher: Frontiers Media SA

Published: 2024-02-09

Total Pages: 106

ISBN-13: 2832544525

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Neurorehabilitation is a complex and growing field of motor rehabilitation. It is specifically directed to apply restorative techniques to stimulate neural plasticity of the central nervous system (CNS). Considering that neuroplasticity is maintained for the whole human life and can be stimulated through specific learning or exposure to enriched environments, we can hypothesize that applying specific treatments can be beneficial for people with CNS injury. Because the plateau of neuroplasticity can be observed after about 12 weeks from stroke onset it is vital to capitalize on this high level of brain reorganization by providing well-timed and well-designed treatments. Here we can distinguish a wide range of approaches developed for CNS recovery in acute, subacute, or chronic stage of injury. These approaches comprise priming or augmentation techniques, including innovative technologies like end-effector robots, exoskeletons, or virtual reality. Many of them have been confirmed as effective, but so far in clinical practice, we can still experience a lack of specific indications i.e., which therapy for how long time and for which patient’s impairment can be applied.


Indwelling Neural Implants

Indwelling Neural Implants

Author: William M. Reichert

Publisher: CRC Press

Published: 2007-12-17

Total Pages: 300

ISBN-13: 1420009303

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Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwel


Converging Clinical and Engineering Research on Neurorehabilitation IV

Converging Clinical and Engineering Research on Neurorehabilitation IV

Author: Diego Torricelli

Publisher: Springer Nature

Published: 2021-10-01

Total Pages: 870

ISBN-13: 3030703169

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The book reports on advanced topics in the areas of neurorehabilitation research and practice. It focuses on new methods for interfacing the human nervous system with electronic and mechatronic systems to restore or compensate impaired neural functions. Importantly, the book merges different perspectives, such as the clinical, neurophysiological, and bioengineering ones, to promote, feed and encourage collaborations between clinicians, neuroscientists and engineers. Based on the 2020 International Conference on Neurorehabilitation (ICNR 2020) held online on October 13-16, 2020, this book covers various aspects of neurorehabilitation research and practice, including new insights into biomechanics, brain physiology, neuroplasticity, and brain damages and diseases, as well as innovative methods and technologies for studying and/or recovering brain function, from data mining to interface technologies and neuroprosthetics. In this way, it offers a concise, yet comprehensive reference guide to neurosurgeons, rehabilitation physicians, neurologists, and bioengineers. Moreover, by highlighting current challenges in understanding brain diseases as well as in the available technologies and their implementation, the book is also expected to foster new collaborations between the different groups, thus stimulating new ideas and research directions.


Brain Neurotrauma

Brain Neurotrauma

Author: Firas H. Kobeissy

Publisher: CRC Press

Published: 2015-02-25

Total Pages: 718

ISBN-13: 1466565993

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With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.


Neurological Rehabilitation, 2/e

Neurological Rehabilitation, 2/e

Author: Janet H. Carr

Publisher: Elsevier India

Published: 2011-07-06

Total Pages: 19

ISBN-13: 8131228851

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Janet Carr and Roberta Shepherd head up a new team of eminent authors for the second edition of this definitive text on neurological physiotherapy. In the first edition, the authors described a model of neurological rehabilitation for individuals with motor dysfunction based on scientific research in the areas of neuromuscular control, biomechanics, motor skill learning, and the link between cognition and action, together with developments in pathology and adaptation. The new edition continues to advance this model while identifying and incorporating the many advances that have occurred in the last decade in the understanding and treatment of adults with neurological conditions, whether caused by accident or disease. Among these advances is the knowledge that the brain retains a plastic potential to reorganize, even in old and/or lesioned brains, and that neural plasticity can be influenced by task-related mental and physical practice in a stimulating environment. There is also an increasing body of knowledge related to the musculoskeletal system's adaptability and the need to prevent length and stiffness- related changes in muscle contractility, together with loss of aerobic fitness and endurance. There is an expanding body of clinical research that appears to support the model provided here. The training guidelines outlined in Neurological Rehabilitation are based on biomechanical constructs and motor relearning research, applied to enhance brain reorganization and muscle contractility, and encourage functional recovery of the patient. It connects science and clinical practice enabling students and practitioners to develop their knowledge and use new clinical methods based on modern scientific understanding. All chapters have been revised, some with the collaboration of five specialists who are engaged in high level scientific research and clinical practice Biomechanical models are presented to provide a framework for action-specific training and exercise to improve performance Clinical guidelines are science- and evidence-based Emphasis is on new approaches to the delivery of neurological rehabilitation that increase the time spent in mental and physical activity, and the intensity of practice and exercise Up-to-date referencing


Neurorehabilitation for Central Nervous System Disorders

Neurorehabilitation for Central Nervous System Disorders

Author: Frans van der Brugge

Publisher: Springer

Published: 2017-10-27

Total Pages: 165

ISBN-13: 3319587382

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This book describes the four most common central nervous disorders (Parkinson, stroke, dementia and multiple sclerosis) by focusing on the similarities of their symptoms. This analysis is necessary in order to determine the appropriate treatment method for individual patients. In physical therapy there are various methods available for treating patients affected by a neurological disease, yet the method presented here is the only one to include systematic interventions adapted to the patient’s needs, which are determined by means of a health situation analysis. The book offers practical and applicable information for allied health professionals seeking interventions to help patients function better in their own environment. In addition, this book features updated information on the “van der Brugge method,” focusing on a targeted program to stimulate movement in the elderly with dementia. This book will be of interest to neurologists and physiotherapist s.


Central Nervous System Cancer Rehabilitation

Central Nervous System Cancer Rehabilitation

Author: Adrian Cristian

Publisher: Saunders

Published: 2018-08-29

Total Pages: 0

ISBN-13: 9780323548298

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Rehabilitation of a person with cancer of the brain and spinal cord requires individualized care by a team of specialists from time of initial diagnosis through active treatment, survivorship, and advanced stages of the disease. The purpose of this book is to provide useful information to assist these clinicians in the noble endeavor of rehabilitating individuals diagnosed and treated for cancer of the central nervous system with the goal of maximizing the level of function and quality of life. This book begins with a description of the cancer rehabilitation continuum of care, safety considerations, and functional outcomes. The section on brain cancer provides content on neurosurgical management, rehabilitation, cognitive deficits, communication, and swallowing impairments. The section on spinal cord cancer provides the reader with information on characteristics of spinal cord tumors, neurosurgical management, and rehabilitation. A chapter on rehabilitation of the child with brain and spinal cord cancer addresses the unique needs of this population. Pain and fatigue are very common concerns raised by persons with cancer of the central nervous system, and these topics are covered as well. The final chapter covers the equally important topic of the role of palliative rehabilitation in advanced cancer--page ix.


Oxford Textbook of Neurorehabilitation

Oxford Textbook of Neurorehabilitation

Author: Volker Dietz

Publisher: Oxford University Press, USA

Published: 2015

Total Pages: 473

ISBN-13: 0199673713

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Part of the Oxford Textbooks in Clinical Neurology series, this textbook will provide the reader with an understanding of the theoretical underpinnings of neurorehabilitation, as well as a clear idea about how (and why) to approach treatment decisions in individual patients.