Natural Small Molecule Drugs from Plants
Natural Small Molecule Drugs from Plants

Author: Guan-Hua Du

Publisher: Springer

Published: 2018-11-19

Total Pages: 702

ISBN-13: 9811080224

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This book discusses 120 types of natural, small-molecule drugs derived from plants. They are grouped into 7 parts according their clinical uses, such as drugs for cardiovascular diseases, for metabolic diseases, for neuropsychiatric diseases, for immune-mediated inflammatory diseases, anti-tumor drugs, and drugs for parasites and bacterial infection. Each chapter systematically summarizes one drug, including its physicochemical properties, sources, pharmacological effects and clinical applications. To help readers understand the drug better, the research and pharmacological activity for each drug is also described, which serves as a salutary lesson for future drug development. Written by frontline researchers, teachers and clinicians working in field of pharmacy and pharmacology it provides an overview of natural, small-molecule drugs derived from plants for researchers in the field.

Natural Products
Natural Products

Author: Lixin Zhang

Publisher: Springer Science & Business Media

Published: 2007-11-17

Total Pages: 380

ISBN-13: 1592599761

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A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.

Biodiversity
Biodiversity

Author: National Academy of Sciences/Smithsonian Institution

Publisher: National Academies Press

Published: 1988-01-01

Total Pages: 535

ISBN-13: 0309037395

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This important book for scientists and nonscientists alike calls attention to a most urgent global problem: the rapidly accelerating loss of plant and animal species to increasing human population pressure and the demands of economic development. Based on a major conference sponsored by the National Academy of Sciences and the Smithsonian Institution, Biodiversity creates a systematic framework for analyzing the problem and searching for possible solutions.

The Role of Natural Products in Drug Discovery
The Role of Natural Products in Drug Discovery

Author: J. Mulzer

Publisher: Springer Science & Business Media

Published: 2013-04-17

Total Pages: 363

ISBN-13: 3662040425

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Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products. Total synthesis of natural products with interesting biological activities is paving the way for the preparation of new and improved analogs. The methods of combinatorial chemistry permit the selection of the best drug from a large number of candidates. Beyond synthesis and evaluation of organic molecules a number of new bioorganic methods are coming to the fore and will be discucced in this isue of the ERnst schering Research Foundation workshop proceedings.

Herbal Biomolecules in Healthcare Applications
Herbal Biomolecules in Healthcare Applications

Author: Subhash C. Mandal

Publisher: Academic Press

Published: 2021-10-05

Total Pages: 752

ISBN-13: 0323900801

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Herbal Biomolecules in Healthcare Applications presents extensive detailed information on all the vital principles, basics and fundamental aspects of multiple herbal biomolecules in the healthcare industry. This book examines important herbal biomolecules including alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, terpenes, fats and waxes, proteins and peptides, and vitamins. These herbal biomacromolecules are responsible for different bioactivities as well as pharmacological potentials. A systematic understanding of the extraction, purification, characterization, applications of these herbal biomolecules and their derivatives in healthcare fields is developed in this comprehensive book. Chapters explore the key topics along with an emphasis on recent research and developments in healthcare fields by leading experts. They include updated literature review of the relevant key topics, good quality illustrations, chemical structures, flow charts, well-organized tables and case studies. Herbal Biomolecules in Healthcare Applications will be useful for researchers working on natural products and biomolecules with bioactivity and nutraceutical properties. Professionals specializing in scientific areas such as biochemistry, pharmacology, analytical chemistry, organic chemistry, clinics, or engineering focused on bioactive natural products will find this book useful. - Provides a study of different type of biomolecules from herbal extracts and their bioactivities as well as their application in the healthcare industry - Contributions by global leaders and experts from academia, industry and regulatory agencies, who have been considered as pioneers in the application of herbal biomolecules in the diverse healthcare fields - Includes updated literature review along with practical examples and research case studies

Drug Discovery and Development
Drug Discovery and Development

Author: Ramarao Poduri

Publisher: Springer Nature

Published: 2021-02-15

Total Pages: 522

ISBN-13: 9811555346

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This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.

WHO Global Report on Traditional and Complementary Medicine 2019
WHO Global Report on Traditional and Complementary Medicine 2019

Author: World Health Organization

Publisher: World Health Organization

Published: 2019-05-16

Total Pages: 228

ISBN-13: 9241515430

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This report is structured in five parts: national framework for traditional and complementary medicine (T&CM); product regulation; practices and practitioners; the challenges faced by countries; and finally the country profiles. Apart from the section on practices and practitioners the report is consistent with the format of the report of the first global survey in order to provide a useful comparison. The section on practices and practitioners which covers providers education and health insurance is a new section incorporated to reflect the emerging trends in T&CM and to gather new information regarding these topics at a national level. All new information received has been incorporated into individual country profiles and data graphs. The report captures the three phases of progress made by Member States; that is before and after the first WHO Traditional Medicine Strategy (1999?2005) from the first global survey to the second global survey (2005?2012) and from the second survey to the most recent timeline (2012?2018).

Plant-derived Natural Products
Plant-derived Natural Products

Author: Anne E. Osbourn

Publisher: Springer Science & Business Media

Published: 2009-07-07

Total Pages: 588

ISBN-13: 0387854983

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Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.

Recent Advances in Plant-Based, Traditional, and Natural Medicines
Recent Advances in Plant-Based, Traditional, and Natural Medicines

Author: Subramayam Vemulpad

Publisher: CRC Press

Published: 2014-02-24

Total Pages: 392

ISBN-13: 1482243598

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The purpose of this book is to discuss several medicinal plants to find wider application in the domain of medicinal, clinical, and pharmaceutical treatment. Recent Advances in Plant-Based, Traditional, and Natural Medicines serves as a useful source of ideas and an inspiration for further cell and molecular biology research toward developing drugs

Modern Phytomedicine
Modern Phytomedicine

Author: Iqbal Ahmad

Publisher: John Wiley & Sons

Published: 2006-12-13

Total Pages: 404

ISBN-13: 3527609539

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This timely and original handbook paves the way to success in plant-based drug development, systematically addressing the issues facing a pharmaceutical scientist who wants to turn a plant compound into a safe and effective drug. Plant pharmacologists from around the world demonstrate the potentials and pitfalls involved, with many of the studies and experiments reported here published for the first time. The result is a valuable source of information unavailable elsewhere.