This book reviews the latest advances and biomedical applications of nanozymes, which are artificial nanomaterials exhibiting enzymatic properties similar to natural enzymes, but with less limitations than natural enzymes. Nanozymes display advantages such as facile synthesis, easy surface modification, improved stability, higher catalytic power, and target-specific binding. Nanozymes containing metals, metal oxides, carbon, and metal sulfide are actually used for cancer therapy, biomolecules sensing, bioimaging, disease diagnostics and diabetes management. The book discloses underlying mechanisms, concepts, recent trends, constraints, and prospects for nanomedicine using nanozymes.
This book describes the fundamental concepts, the latest developments and the outlook of the field of nanozymes (i.e., the catalytic nanomaterials with enzymatic characteristics). As one of today’s most exciting fields, nanozyme research lies at the interface of chemistry, biology, materials science and nanotechnology. Each of the book’s six chapters explores advances in nanozymes. Following an introduction to the rise of nanozymes research in the course of research on natural enzymes and artificial enzymes in Chapter 1, Chapters 2 through 5 discuss different nanomaterials used to mimic various natural enzymes, from carbon-based and metal-based nanomaterials to metal oxide-based nanomaterials and other nanomaterials. In each of these chapters, the nanomaterials’ enzyme mimetic activities, catalytic mechanisms and key applications are covered. In closing, Chapter 6 addresses the current challenges and outlines further directions for nanozymes. Presenting extensive information on nanozymes and supplemented with a wealth of color illustrations and tables, the book offers an ideal guide for readers from disparate areas, including analytical chemistry, materials science, nanoscience and nanotechnology, biomedical and clinical engineering, environmental science and engineering, green chemistry, and novel catalysis.
This book presents the state-of-the-art advances and applications of nanozymes, the recently developing branch of enzymology that synthesizes and uses nanomaterials that mimic the function of traditional enzymes. During the past decade, the study of nanozymes has grown rapidly. Several new nanomaterials that exhibit enzymatic actions have been identified, along with new applications for their practical use. This book draws upon the work of experts from around the world and provides an in-depth analysis and cutting-edge overview of nanozymes, with an eye toward their present and future applications. Chapters are arranged in a logical order to provide physio-chemical characterization of nanozyme and basic mechanisms of their enzymatic actions. Focusing on current limitations of nanozymes and their reaction kinetics, the book presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. It also focuses on traditional and novel nanozyme applications, such as biosensing, drug delivery, and disease therapy, as well as their use as antibacterials. An important addition in this book is the summary of emerging literature on nanozyme toxicology. This book is intended as a ready reference for advanced undergraduate and graduate students doing research in nanotechnology; materials science; chemistry; and chemical, biological, biomedical, and food engineering. Research and development scientists, engineers, and technologists working in the chemical and biological/biomedical industries will gain much from the materials in this book for their industry practice. Presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. Discusses metal organic frameworks as nanozymes. Reviews on traditional and novel nanozyme applications, such as biosensing, drug delivery, disease therapy, and their use as antibacterials. Examines nanozyme toxicology. Dr. Sundaram Gunasekaran is a Professor in the Department of Biological Systems Engineering at the University of Wisconsin-Madison.
This book introduces the new concept of “nanozyme”, which refers to nanomaterials with intrinsic enzymatic activity, rather than nanomaterials with biological enzymes incorporated on the surface. The book presents the cutting-edge advances in nanozyme, with emphasis on state-of-the-art applications in many important fields, such as in the biomedical fields and for environmental protection. The nanozyme is a totally new type of artificial enzyme and exhibits huge advantages over natural enzymes, including greater stability, low cost, versatility, simplicity, and suitability for industry. It is of interest to university researchers, R&D engineers, as well as graduate students in nanoscience and technology, and biology wishing to learn the core principles, methods, and the corresponding applications of “nanozyme”.
Nanozymes: A Revolutionary Perspective on Approachable Bio-applications provides an in-depth overview of nanozymes, with a special focus on nanozymes synthesis and their various applications in biological sciences. The book starts with introductory chapters exploring the enzymatic mechanism of nanozymes and providing the concept of engineering to surface modification to achieve enhanced nanozymatic properties. Subsequent chapters focus on the application of nanozymes in many different fields, including biomedical science, agriculture, environmental science and more.This work is an important reference source for worldwide materials scientists and researchers interested on the resent developments, challenges, and future directions of nanozymes research. Highlights recent developments and future directions of nanozymes research for readers across multidisciplinary fields Features a broad range of applications of nanozymes, from environmental monitoring to therapeutic applications Includes numerous illustrations to help readers easily understand the role of nanozymes-based tools in different areas
This book presents the state-of-the-art advances and applications of nanozymes, the recently developing branch of enzymology that synthesizes and uses nanomaterials that mimic the function of traditional enzymes. During the past decade, the study of nanozymes has grown rapidly. Several new nanomaterials that exhibit enzymatic actions have been identified, along with new applications for their practical use. This book draws upon the work of experts from around the world and provides an in-depth analysis and cutting-edge overview of nanozymes, with an eye toward their present and future applications. Chapters are arranged in a logical order to provide physio-chemical characterization of nanozyme and basic mechanisms of their enzymatic actions. Focusing on current limitations of nanozymes and their reaction kinetics, the book presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. It also focuses on traditional and novel nanozyme applications, such as biosensing, drug delivery, and disease therapy, as well as their use as antibacterials. An important addition in this book is the summary of emerging literature on nanozyme toxicology. This book is intended as a ready reference for advanced undergraduate and graduate students doing research in nanotechnology; materials science; chemistry; and chemical, biological, biomedical, and food engineering. Research and development scientists, engineers, and technologists working in the chemical and biological/biomedical industries will gain much from the materials in this book for their industry practice. Presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. Discusses metal organic frameworks as nanozymes. Reviews on traditional and novel nanozyme applications, such as biosensing, drug delivery, disease therapy, and their use as antibacterials. Examines nanozyme toxicology. Dr. Sundaram Gunasekaran is a Professor in the Department of Biological Systems Engineering at the University of Wisconsin–Madison.
This volume explores some of the most exciting recent advances in basic research on nanoparticles in translational science and medicine and how this knowledge is leading to advances in the various fields. This series provides a forum for discussion of new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields
This handbook explains the application of nanoparticles in medical diagnosis and treatment. It is a ready reference on the subject, starting with the introduction to nanoparticles and progressing to synthetic procedures for nanotherapeutics, human disease diagnosis and nanocarrier-based drug delivery. The book also covers information about specific nanoparticle conjugates, in which nanoparticles are combined with drugs or nucleic acid strands (DNA, siRNAs, shRNAs, miRNAs) as well as topics of relevant to this field such as immunotherapy and vaccination development strategies. Each chapter also provides references for further reading. A Comprehensive Guide to Nanoparticles in Medicine is an ideal resource for scholars in medicine, pharmacology and technology who require an understanding to some basic facets of nanoparticles.
This book presents and discusses recent developments in the broad field of spectroscopy, providing the reader with an updated overview. The main objective is to introduce them to recent innovations and current trends in spectroscopy applied to molecules and materials. The book also brings together experimentalists and theoreticians to highlight the multidimensional aspects of spectroscopy and discuss the latest issues. Accordingly, it provides insights not only into the general goals of spectroscopy, but also into how the various spectroscopic techniques represent a toolbox that can be used to gain a more detailed understanding of molecular systems and complex chemical problems. Besides technical aspects, basic theoretical interpretations of spectroscopic results are also presented. The spectroscopy techniques discussed include UV-visible absorption spectroscopy, Raman spectroscopy, IR absorption spectroscopy, fluorescence spectroscopy, and time-resolved spectroscopy. In turn, basic tools like lasers and theoretical modeling approaches are also presented. Lastly, applications for the characterization of fundamental properties of molecules (environmental aspects, biomolecules, pharmaceutical drugs, hazardous molecules, etc.) and materials (nanomaterials, nuclear chemistry materials, biomaterials, etc.) are discussed. Given its scope, the book offers a valuable resource for researchers from various branches of science, and presents new techniques that can be applied to their specific problems.
