High Resolution Imaging in Microscopy and Ophthalmology
High Resolution Imaging in Microscopy and Ophthalmology

Author: Josef F. Bille

Publisher: Springer

Published: 2019-08-13

Total Pages: 411

ISBN-13: 3030166384

DOWNLOAD EBOOK

This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.

Multimodal Retinal Imaging
Multimodal Retinal Imaging

Author: Amresh Chopdar

Publisher: JP Medical Ltd

Published: 2014-08-22

Total Pages: 188

ISBN-13: 1907816607

DOWNLOAD EBOOK

span style="font-size: xx-small;"Retinal imaging techniques are used to diagnose and screen for various conditions such as macular degeneration and glaucoma. Equally importantly, they are used to monitor the progression of previously diagnosed conditions.

Microperimetry and Multimodal Retinal Imaging
Microperimetry and Multimodal Retinal Imaging

Author: Edoardo Midena

Publisher: Springer Science & Business Media

Published: 2013-12-12

Total Pages: 200

ISBN-13: 364240300X

DOWNLOAD EBOOK

Microperimetry allows precise functional examination of the retina and optic nerve and is especially valuable for evaluation of the macular area. This fully up-to-date textbook on microperimetry, written by leading experts in the field, will also serve as an atlas and diagnostic reference. It is designed for use by both ophthalmologists and optometrists in daily clinical practice and clinical research, and the contents thus range from basic technical information to the most advanced clinical applications. Past and current microperimetry techniques are reviewed, and the role of microperimetry in the context of multimodal imaging scenario is explained. The full range of clinical applications is then discussed, including age-related macular degeneration, diabetes, myopia, retinal dystrophies, disorders of the vitreoretinal interface, inflammatory chorioretinal diseases, toxic retinopathies, glaucoma, and low vision.

Retinal Degenerative Diseases
Retinal Degenerative Diseases

Author: Matthew M. LaVail

Publisher: Springer Science & Business Media

Published: 2011-12-21

Total Pages: 867

ISBN-13: 1461406315

DOWNLOAD EBOOK

This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.

Computational Retinal Image Analysis
Computational Retinal Image Analysis

Author: Emanuele Trucco

Publisher: Academic Press

Published: 2019-11-20

Total Pages: 504

ISBN-13: 0081028164

DOWNLOAD EBOOK

Computational Retinal Image Analysis: Tools, Applications and Perspectives gives an overview of contemporary retinal image analysis (RIA) in the context of healthcare informatics and artificial intelligence. Specifically, it provides a history of the field, the clinical motivation for RIA, technical foundations (image acquisition modalities, instruments), computational techniques for essential operations, lesion detection (e.g. optic disc in glaucoma, microaneurysms in diabetes) and validation, as well as insights into current investigations drawing from artificial intelligence and big data. This comprehensive reference is ideal for researchers and graduate students in retinal image analysis, computational ophthalmology, artificial intelligence, biomedical engineering, health informatics, and more.

Retinal and Choroidal Imaging in Systemic Diseases
Retinal and Choroidal Imaging in Systemic Diseases

Author: Jay Chhablani

Publisher: Springer

Published: 2017-12-29

Total Pages: 309

ISBN-13: 9811054614

DOWNLOAD EBOOK

This book explains the underlying rationale for retinal and choroidal imaging in the context of systemic diseases. Various systemic diseases involve the eyes, and for some, the eyes could provide the first clue to their presence. Advances in posterior segment imaging have significantly improved our understanding of the pathophysiology and management of posterior segment diseases. However, imaging techniques like enhanced depth imaging, oximetry, adaptive optics, and retinal blood flowmetry have remained largely unexplored in connection with systemic diseases. Enhancing the available literature on the use of such imaging techniques for various systemic diseases, this handbook will help readers understand their pathomechanisms, supporting early diagnosis and more targeted therapeutic approaches. As such, it offers an essential resource for ophthalmologists, especially those with predominantly vitreo-retinal and uvea experience.

Fluorescence Lifetime Imaging Ophthalmoscopy
Fluorescence Lifetime Imaging Ophthalmoscopy

Author: Martin Zinkernagel

Publisher: Springer

Published: 2019-07-29

Total Pages: 123

ISBN-13: 3030228789

DOWNLOAD EBOOK

This book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies. This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis. Written by a team of expert leaders within this field, this book will be relevant for scientists and clinicians with an interest in ophthalmoscopy.

Tau Protein
Tau Protein

Author: Caroline Smet-Nocca

Publisher: Humana

Published: 2024-04-29

Total Pages: 0

ISBN-13: 9781071636282

DOWNLOAD EBOOK

This volume explores the latest advancements and techniques to study Tau protein that include basic and advanced methods and protocols from in vitro assays to in vivo models that address the molecular and functional aspects of tau physiopathology and many of its related technical issues. The chapters in this book are organized into five parts: Part One describes conformational and functional studies of native tau protein using wet and non-wet lab protocols. Part Two looks at in vitro methods to monitor or control the formation of Tau oligomers and fibrils, and the fibrillization process. Part Three provides protocols for the characterization and in vitro introduction of post-translational modifications in Tau protein for further functional studies. Part Four describes analytical tools for the detection of Tau proteins under various forms, factors associated with Tau pathology, and MAPT gene studies. Finally, Part Five explores cellular and in vivo models for the investigations of Tau physiopathology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Tau Proteins: Methods and Protocols, Second Edition is a valuable tool for any researcher interested in learning more about this important and developing field related to Tau protein as a relevant and attractive target for neurodegeneration therapies.

Optical Coherence Tomography in Age-Related Macular Degeneration
Optical Coherence Tomography in Age-Related Macular Degeneration

Author: Gabriel Coscas

Publisher: Springer Science & Business Media

Published: 2009-07-25

Total Pages: 392

ISBN-13: 3642014674

DOWNLOAD EBOOK

Rapid or even dramatic progress has been made in the field of AMD over recent years, leading to a constant revision of basic concepts. A wide range of fundus imaging modalities are now available, and this book explains the respective value of each technique. The information provided by OCT is presented logically by comparison with plain films, autofluorescence, fluorescein angiography, or indocyanine green angiography. Meticulous biomicroscopic examination of macular changes and the essential value of fluorescein angiography for the detection of anatomical alterations of the macula and for precise evaluation of lesions and their course by indocyanine green angiography have naturally led the author Gabriel Coscas to analyze the new data provided by OCT.

Diabetes and Fundus OCT
Diabetes and Fundus OCT

Author: Ayman S. El-Baz

Publisher: Elsevier

Published: 2020-04-03

Total Pages: 434

ISBN-13: 0128174404

DOWNLOAD EBOOK

Diabetes and Fundus OCT brings together a stellar cast of authors who review the computer-aided diagnostic (CAD) systems developed to diagnose non-proliferative diabetic retinopathy in an automated fashion using Fundus and OCTA images. Academic researchers, bioengineers, new investigators and students interested in diabetes and retinopathy need an authoritative reference to bring this multidisciplinary field together to help reduce the amount of time spent on source-searching and instead focus on actual research and the clinical application. This reference depicts the current clinical understanding of diabetic retinopathy, along with the many scientific advances in understanding this condition. As the role of optical coherence tomography (OCT) in the assessment and management of diabetic retinopathy has become significant in understanding the vireo retinal relationships and the internal architecture of the retina, this information is more critical than ever.