Multifunctional And Targeted Theranostic Nanomedicines

Multifunctional And Targeted Theranostic Nanomedicines

Author: Keerti Jain

Publisher: Springer Nature

Published: 2023-08-23

Total Pages: 417

ISBN-13: 9819905389

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This book discusses approaches based on multifunctional and targeted theranostic nanomedicines for improving diagnosis and drug delivery. It explores nanomedicines based on nanocarriers like liposomes, ethosomes, niosomes, polymeric nanoparticles, lipidic nanoparticles, metallic nanoparticles, micelles, dendrimers, quantum dots, carbon-based nanomaterials including carbon nanotubes, carbon dots, carbon quantum dots, graphene oxide, and fullerene. This book reviews designing, conjugation, optimization, formulation and development, and scale-up of multifunctional and targeted theranostic nanomedicines. It examines major challenges in developing nanomaterials that can be applied to nanomedicine with high biocompatibility and biodegradability for diagnostic and therapeutic purposes. Lastly, it addresses the most promising approaches at both commercialization and regulatory steps for bringing theranostic nanomedicine from research laboratories to clinics for patient use. ​


Multifunctional Theranostic Nanomedicines in Cancer

Multifunctional Theranostic Nanomedicines in Cancer

Author: Malay K. Das

Publisher: Academic Press

Published: 2021-03-16

Total Pages: 428

ISBN-13: 0128217006

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Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. - Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines - Discusses treatment options from a pharmaceutical sciences perspective - Includes translational science and targeted CNS cancer treatment


Design of Nanostructures for Theranostics Applications

Design of Nanostructures for Theranostics Applications

Author: Alexandru Mihai Grumezescu

Publisher: William Andrew

Published: 2017-11-30

Total Pages: 695

ISBN-13: 0128136707

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Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry. - Explores how the design of a range of nanomaterials make them effective theranostic agents, including multifunctional core-shell nanostructures, mesoporous silica nanoparticles, and quantum dots - Shows how nanomaterials are used effectively for a range of diseases, including breast cancer, prostate cancer and neurological disorders - Assesses the pros and cons of using different nanomaterials for different types of treatment


Handbook of Nanomaterials for Cancer Theranostics

Handbook of Nanomaterials for Cancer Theranostics

Author: Joao Conde

Publisher: Elsevier

Published: 2018-06-27

Total Pages: 608

ISBN-13: 0128133406

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Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. - Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics - Explores the regulatory hurdles facing theranostic nanomedicine - Discusses how the use of nanomaterials can help create more effective cancer treatments


Nanotheranostics For Personalized Medicine

Nanotheranostics For Personalized Medicine

Author: Patrick Couvreur

Publisher: World Scientific

Published: 2016-02-22

Total Pages: 346

ISBN-13: 9814713546

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The application of nanotechnology in the biomedical field, known as nanomedicine, has gained much interest in the recent past as a versatile strategy for selective drug delivery and diagnostic purposes. The nanotheranostic approach, which aims to combine both therapeutic and imaging/diagnostic functionalities, is characterized by a strong pluridisciplinarity where the chemistry of materials, bioconjugate chemistry, pharmaceutical technology, drug delivery, imaging, and pharmacology, work together. Nanotheranostics combine simultaneous non-invasive diagnosis and treatment of diseases with the exciting possibility to monitor drug release and distribution in real time; thus offering the opportunity to optimize treatment outcomes in cancer and other severe diseases. Clinical applications of nanotheranostics would enable earlier detection and treatment of diseases, and earlier assessment of the response, thus allowing to identify patients which would potentially respond to therapy and have higher possibilities of a favorable outcome.Nanotheranostics for Personalized Medicine presents an integrated and transdisciplinary description of nanotheranostics. It provides principles of imaging techniques and concrete examples of advances and challenges in the development of nanotheranostics for personalized medicine.This book is written for students (Bachelors to Doctoral level) as well as experienced researchers, in academia or the industry, interested in this emerging concept in the nanomedicine field.


Frontiers of Engineering

Frontiers of Engineering

Author: National Academy of Engineering

Publisher: National Academies Press

Published: 2019-02-28

Total Pages: 125

ISBN-13: 0309487501

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This volume presents papers on the topics covered at the National Academy of Engineering's 2018 US Frontiers of Engineering Symposium. Every year the symposium brings together 100 outstanding young leaders in engineering to share their cutting-edge research and innovations in selected areas. The 2018 symposium was held September 5-7 and hosted by MIT Lincoln Laboratory in Lexington, Massachusetts. The intent of this book is to convey the excitement of this unique meeting and to highlight innovative developments in engineering research and technical work.


Nano Medicine and Nano Safety

Nano Medicine and Nano Safety

Author: Malay K. Das

Publisher: Springer Nature

Published: 2020-12-09

Total Pages: 634

ISBN-13: 9811562555

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This book reviews the application of Nanobiotechnology in the development of Nanomedicine, while also discussing the latest trends and challenges in the clinical translation of Nanomedicine. Nanomedicine refers to the application of Nanotechnology to medicine and holds tremendous potential for achieving improved efficiency, bioavailability, dose response, personalized medicine and enhanced safety as compared to conventional medicines. The book first introduces readers to the basic concepts of Nanomedicine, and to technological advances in and applications of Nanotechnology in treatment, diagnosis, monitoring, and drug delivery. In turn, it reviews the current status of multi-functionalization strategies for using Nanoparticles in the targeted delivery of therapeutic agents. The book’s third and final section focuses on the regulatory and safety challenges posed by Nanomedicine, including industry and regulatory agencies’ efforts to address them.


Inorganic Frameworks as Smart Nanomedicines

Inorganic Frameworks as Smart Nanomedicines

Author: Alexandru Mihai Grumezescu

Publisher: William Andrew

Published: 2018-04-09

Total Pages: 727

ISBN-13: 0128136626

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Inorganic Frameworks as Smart Nanocarriers for Drug Delivery brings together recent research in the area of inorganic frameworks for drug delivery. Different types of nanocarriers are presented and discussed in detail, providing an up-to-date overview on inorganic nanoparticles with pharmaceutical applications. Written by a diverse range of international academics, this book is a valuable reference resource for researchers in biomaterials, the pharmaceutical industry, and those who want to learn more about the current applications of inorganic smart nanocarriers. - Includes assembly methods for a variety of smart nanocarrier systems, also showing how they are applied - Highlights how metal-oxide nanoparticles are effectively used in drug delivery - Assesses the pros and cons of different metallic nanomaterials as drug carriers


Bioactive Compounds of Edible Oils and Fats

Bioactive Compounds of Edible Oils and Fats

Author: Leo M.L. Nollet

Publisher: CRC Press

Published: 2024-10-09

Total Pages: 333

ISBN-13: 1040126979

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Edible oils and fats are derived from plants and animals and have several health benefits. Edible oils and fats consist of many health-promoting bioactive compounds such as polyunsaturated fatty acids, monounsaturated fatty acids, polyphenols, flavonoids, phytosterols, vitamins, and inorganic compounds. The chemical compounds present in edible oils and fats are known for their possible health risks such as coronary heart disease and metabolic diseases, which is why there is a need to check the quality, purity, and safety of edible oils and fats. Bioactive Compounds of Edible Oils & Fats: Health Benefits, Risks, and Analysis provides an overview of different edible oils and fats, health benefits, associated risks, and analytical techniques for qualitative and quantitative guidelines for ensuring their quality and safety using modern analytical tools and techniques. This book will provide an important guideline for controlling quality, safety, and efficacy issues related to edible oils and fats. Key Features: Provides a detailed overview of different edible oils and fats of plant and animal origin, chemistry, and identification methods. Describes their health benefits, risks, and the use of different analytical techniques in quality control. Describes the applicability of sophisticated analytical techniques such as GC-FID, GC-MS, and HPLC for quality control of edible oils and fats. Emphasizes the use of recent techniques such as LC-MS and FTIR-chemometrics in the analysis and quality control of edible oils and fats.


Advances in Metallodrugs

Advances in Metallodrugs

Author: Shahid Ul Islam

Publisher: John Wiley & Sons

Published: 2020-07-08

Total Pages: 432

ISBN-13: 1119640423

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This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application areas of newly discovered metallodrugs. It can prove beneficial for researchers, investigators and scientists whose work involves inorganic and coordination chemistry, medical science, pharmacy, biotechnology and biomedical engineering.