Multi-Pronged Omics Technologies to Understand COVID-19

Multi-Pronged Omics Technologies to Understand COVID-19

Author: Sanjeeva Srivastava

Publisher: CRC Press

Published: 2022-07-07

Total Pages: 237

ISBN-13: 1000595609

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"COVID-19 and Omics Technologies" is a comprehensive, integrative assessment of recent information and knowledge collected on SARS-CoV-2 and COVID-19 during the pandemic based on omics technologies. It demonstrates how omics technologies could better investigate the infectious disease and propose solutions to the current concerns. The value of multi-omics technologies in understanding disease etiology and host response, discovering infection biomarkers and illness prediction, identifying vaccine candidates, discovering therapeutic targets, and tracing pathogen evolution is discussed in this book. These factors combine to make it a valuable resource to enhance understanding of both "Omics technology" and "COVID-19" as a disease. The book covers the most recent understanding of COVID-19 and the applications of cutting-edge studies, making it accessible to a large multidisciplinary readership. The book explains how high-throughput technologies and systems biology might assist to solve the pandemic’s challenges and deconstruct and appreciate the substantial contributions that omics technologies have made in predicting the path of this unforeseeable pandemic. Features: In-depth summary of clinical presentation, epidemiological impact, and long-term sequelae of COVID-19 pandemic. A systematic overview of omics-based approaches to the study of COVID-19 biology. Recent research results and some pointers to future advancements in methodologies used. Detailed examples from recent studies on COVID-19 encompassing different omics methodologies. A detailed description of methodologies and notes on the applications of state-of-the-art technologies. This book is intended for scientists who need to understand the biology of COVID-19 from the perspective of omics investigations, as well as researchers who want to employ omics-based technologies in disease biology.


The Sage Handbook of Online Higher Education

The Sage Handbook of Online Higher Education

Author: Safary Wa-Mbaleka

Publisher: SAGE Publications Limited

Published: 2023-11-01

Total Pages: 933

ISBN-13: 1529673003

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The SAGE Handbook of Online Higher Education presents a cutting-edge collection of 50 essays that explores the rapidly evolving landscape of online teaching and learning in higher education. Assembled and contributed by a team of leading experts, the Handbook adopts a uniquely holistic approach to examining the needs of online education. Chapters bring together voices from diverse and international backgrounds to provide insights applicable to a broad range of contexts, and present practical strategies for planning, delivering quality online higher education. The handbook covers a wide range of topics, including online pedagogy, instructional design, student engagement, technological innovation, assessment, leadership, and the developing role of online education in the context of broader societal and cultural shifts. The SAGE Handbook of Online Higher Education is an essential resource for educators, researchers, policymakers, and practitioners who seek to understand and shape the future of higher education in the digital age. Section 1: Fundamentals of Online Education Section 2: Online Education Around the World Section 3: Online Instructional Design Section 4: Online Instructional Delivery Section 5: Instructional Technology for Online Education Section 6: Online Education Administration and Management Section 7: Student Support Services


My Kitchen Table: 100 Cakes and Bakes

My Kitchen Table: 100 Cakes and Bakes

Author: Mary Berry

Publisher: Random House

Published: 2011

Total Pages: 210

ISBN-13: 184990149X

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Mary Berry is the undisputed queen of cakes and here she shares her foolproof recipes for a classic victoria sponge, the perfect cupcake, her very best chocolate cake and a quick fruit cake among many others. Cook with confidence - 100 of Mary's best-loved recipes For more recipes, video masterclasses and cooking tips as well as our newsletter and reader offers, see www.mykitchentable.co.uk


Rathmines

Rathmines

Author: Seamus Ó Maitiú

Publisher:

Published: 2021-09

Total Pages: 152

ISBN-13: 9781911479789

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This new historical atlas of Rathmines explores the vibrant Dublin suburb through word, map and image. The emergence of Rathmines from village through township to suburb of Dublin is explained in a thoroughly researched text, illustrated with thematic maps, early views and photographs. A series of historic maps shows how the topography changed from medieval ráth to early modern castle, and from nineteenth century village to wealthy residential suburb, local government administrative centre and twentieth-century flatland. A gazetteer of over 1,000 sites and accompanying essay gives the detailed topographical history of Rathmines from earliest times up to c. 1970.Through the atlas, we discover that over the centuries Rathmines has shifted north, its ancient core centred on the original Rathmines Castle (present-day Palmerston Park). Farms gave way to country villas, before the Grand Canal, Portobello Barracks, fine terraces and grand squares from the nineteenth century left their lasting imprint. We are shown how well-known aspects of Rathmines topography, such as Rathmines Road and the Town Hall, have transformed and endured through time. While other once distinctive features -- the Swan River, the world-famous Grubb's astronomical works and two large skating rinks -- have disappeared.Rathmines by Séamas Ó Máitiú is the second in a series of atlases devoted to Dublin suburbs being produced by the Irish Historic Towns Atlas project in the Royal Irish Academy, in association with Dublin City Council. Clontarf by Colm Lennon was published in 2017.


Experimental Models of Multiple Sclerosis

Experimental Models of Multiple Sclerosis

Author: Ehud Lavi

Publisher: Springer Science & Business Media

Published: 2008-01-03

Total Pages: 892

ISBN-13: 0387255184

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Multiple Sclerosis (MS) is an enigmatic immune mediated disease of the central nervous system that affects about 350,000 individuals in the US, and many more around the world. The mechanism of this disease is largely unknown and there is no cure for it. However, there are several well-characterized experimental animal models that help us understand and speculate about potential mechanisms of pathology in this disease. Many of the experimental therapies designed for this disease rely on testing the drugs in animal models before using it in clinical trials. This book combines for the first time the different experimental models for MS (including immune-mediated and viral) under one roof, and highlights aspects that are different or shared among these experimental models. It’s aim is to improve our understanding of this devastating disease and help us think about potential additional therapies for it.


Activity-Based Protein Profiling

Activity-Based Protein Profiling

Author: Benjamin F. Cravatt

Publisher: Springer

Published: 2019-01-25

Total Pages: 420

ISBN-13: 3030111431

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This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions.


Immunoregulation

Immunoregulation

Author: Nicola Fabris

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 473

ISBN-13: 1468445472

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Immunoregulation is one of the areas which has witnessed the most explosive advances of immunology during the past decade. It is in this area that the current view of the immune system has arisen and developed. There is indeed little doubt that immune reactions are primarily determined by messages which are genera ted within the immune system and passed among different types of immunologie cells. This cell communication not only determines the type, intensity and duration of the response after perturbation of the immune system by exogenous antigens, but it is also essential for preventing autoimmune reactions and their clinical conse quences. In order to assure aperfect balance within the enormous com plexity of the immune system, it is not surprising that multiple self-regulatory mechanisms are organized at different levels, such as antibody feedback, idiotypic-anti-idiotypic responses, suppres sor and helper T cells, lymphokine signals and genetic require ments. A nu mb er of observations in recent years have, however, demonstrated that consistent contributions to the immunological homeostasis are given also by signals generated outside of the immune system, namely,in the central and autonomous nervous system as weIl as in the endocrine apparatus. Furthermore, the interactions between the immune system and the other body homestatic mechanisms seem to be bidirectional: if immunological cells may be targets of neuroendocrinological factors, immunological products seem in turn to contribute to the neuro endocrine homeostasis.


Oral Mucosal Immunity and Microbiome

Oral Mucosal Immunity and Microbiome

Author: Georgios N. Belibasakis

Publisher: Springer Nature

Published: 2019-11-15

Total Pages: 192

ISBN-13: 3030285243

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The first International Conference on Oral Mucosal Immunity and Microbiome (OMIM) aimed to highlight cutting-edge basic and translational research from an oral immunological and microbiological perspective. Oral diseases with a microbial etiology are the most prevalent chronic diseases of humans. Whilst not life-threatening, they can significantly compromise quality of life, are associated with increased risk for certain systemic diseases, and pose heavy financial burdens to national health systems. Hence, periodontal and peri-implant diseases, dental caries, root canal infections and mucosal infections are significant global public health problems. In this book global experts summarize and discuss the latest progress made in oral mucosal immunity and the oral microbiome. Target audience is basic and/or translational researchers with expertise in host immunity and microbiome research, and interest in oral health and disease. This volume provides a much needed quantum leap in the field, by joining forces to address gaps at the oral mucosal immunity-microbiome cross-talk.


Tools and Trends in Bioanalytical Chemistry

Tools and Trends in Bioanalytical Chemistry

Author: Lauro Tatsuo Kubota

Publisher: Springer Nature

Published: 2021-11-25

Total Pages: 559

ISBN-13: 3030823814

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This textbook covers the main tools and techniques used in bioanalysis, provides an overview of their principles, and offers several examples of their application and future trends in diagnosis. Chapters from expert contributors explore the role of bioanalysis in different areas such as biochemistry, physiology, forensics, and clinical diagnosis, including topics from sampling/sample preparation, chemometrics in bioanalysis to the latest techniques used in the field. Particular attention is given to the recent advances in the application of mass spectrometry, NMR, electrochemical methods and separation techniques in bioanalysis. Readers will also find more about the application of microchip-based devices and analytical microarrays. This textbook will appeal to graduate/advanced undergraduate students in Chemistry, Biology, Biochemistry, Pharmacy, and Chemical Engineering. It is also a useful resource for researchers and professionals working in the fields of biomedicine and veterinary sciences, with clear explanations and examples of how the different bioanalytical devices are applied for clinical diagnosis.