Molecular Mechanisms Underlying Assembly and Maintenance of the Neuromuscular Junction
Author: Ruth Herbst
Publisher: Frontiers Media SA
Published: 2022-01-17
Total Pages: 241
ISBN-13: 2889740404
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Neuroscientific Foundations of Anesthesiology
Author: George A. Mashour
Publisher: Oxford University Press
Published: 2011-10-05
Total Pages: 296
ISBN-13: 0190453303
DOWNLOAD EBOOKAlthough the perioperative care of patients by anesthesiologists draws on diverse clinical skills, the principles of anesthesiology and pain management are rooted in the neurosciences. The Neuroscientific Foundations of Anesthesiology thoroughly examines the anesthetic modulation of the central, peripheral, and autonomic nervous systems and will help redefine anesthesiology as a fundamentally neuroscientific field. The book is organized by sections, with each focusing on a different part of the nervous system. State-of-the-art chapters written by thought-leaders in anesthesiology and neuroscience provide a novel and invaluable resource.
Anesthetic Pharmacology
Author: Alex S. Evers
Publisher: Cambridge University Press
Published: 2011-03-10
Total Pages: 2902
ISBN-13: 1139497022
DOWNLOAD EBOOKIn recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.
Translational Research in Traumatic Brain Injury
Author: Daniel Laskowitz
Publisher: CRC Press
Published: 2016-04-21
Total Pages: 388
ISBN-13: 1498766579
DOWNLOAD EBOOKTraumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Disorders of Voluntary Muscle
Author: George Karpati
Publisher: Cambridge University Press
Published: 2001-07-12
Total Pages: 800
ISBN-13: 9780521650625
DOWNLOAD EBOOKRewritten and redesigned, this remains the one essential text on the diseases of skeletal muscle.
Electrodiagnosis in Diseases of Nerve and Muscle
Author: Jun Kimura
Publisher: Oxford University Press
Published: 2013-10
Total Pages: 1177
ISBN-13: 0199738688
DOWNLOAD EBOOKIntended for clinicians who perform electrodiagnostic procedures as an extension of their clinical examination, and for neurologists and physiatrists who are interested in neuromuscular disorders and noninvasive electrodiagnostic methods, particularly those practicing electromyography (EMG) this book provides a comprehensive review of most peripheral nerve and muscle diseases, including specific techniques and locations for performing each test.
Molecular Biology of the Cell
Author:
Publisher:
Published: 2002
Total Pages: 0
ISBN-13: 9780815332183
DOWNLOAD EBOOKMechanisms of Memory
Author: J. David Sweatt
Publisher: Academic Press
Published: 2009-09-28
Total Pages: 362
ISBN-13: 0080959199
DOWNLOAD EBOOKThis fully revised second edition provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader's understanding. - More than 25% new content, particularly expanding the scope to include new findings in translational research. - Unique in its depth of coverage of molecular and cellular mechanisms - Extensive cross-referencing to Comprehensive Learning and Memory - Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples
Spinal Muscular Atrophy
Author: Charlotte J Sumner
Publisher: Academic Press
Published: 2016-10-24
Total Pages: 508
ISBN-13: 0128036869
DOWNLOAD EBOOKSpinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development. This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of care, multifaceted aspects of SMN protein functions and SMA disease pathology, various animal models, and biomarkers, as well as current therapeutic development. This title is ideal for graduate students/postdocs and principal investigators who are already in the SMA field and need to keep updated on recent findings and approaches, and for those who are new to, or would like to join, the field. Likewise, users will find an excellent source of reading for biotech/pharma scientists, clinical researchers, and practitioners, regulators, and patients and their advocacy organizations. Furthermore, this book is a handy reference for researchers and clinicians who may want to apply the research strategies and therapeutic approaches in SMA to other rare diseases. - Provides comprehensive, up-to-date reviews by leading investigators on diverse topics of SMA, including clinical features and patient care, SMN genetics and protein functions, animal models, disease pathology and mechanisms, biomarkers, current therapeutic development, and the role of non-profit organizations in therapeutic development - Written to bridge multiple disciplines and promote better communications among basic scientists, clinical researchers, and health care providers on the latest developments in SMA - Includes outstanding questions and perspectives for future investigations and key references for additional detailed study
Botulinum Neurotoxins
Author: Andreas Rummel
Publisher: Springer
Published: 2015-01-29
Total Pages: 0
ISBN-13: 9783642448898
DOWNLOAD EBOOKThe extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application.
